Phenotype: shortened QRS complex duration

Definition
decrease in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart
Synonyms
shortened QRS duration,  shortened QRS interval,  narrow QRS complex
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QRS complex duration

Total number of significant genotype-phenotype associations: 16

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Ggnbp2
Ggnbp2tm1b(KOMP)Wtsi
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.62×10-07
Mgrn1
Mgrn1em1(IMPC)Tcp
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
1.06×10-06
Acad11
Acad11em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
4.07×10-06
Nhs
Nhsem1(IMPC)Tcp
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
9.83×10-06
Fastkd5
Fastkd5em1(IMPC)J
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
JAX
IMPC
1.45×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
UC Davis
IMPC
2.00×10-05
Thoc6
Thoc6em5(IMPC)Tcp
HET   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.19×10-05
Rbl1
Rbl1tm1b(EUCOMM)Hmgu
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
HMGU
IMPC
2.31×10-05
Prdm12
Prdm12tm2b(EUCOMM)Hmgu
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
2.56×10-05
Plscr1
Plscr1tm1b(EUCOMM)Hmgu
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
ICS
IMPC
4.37×10-05
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
UC Davis
IMPC
6.34×10-05
Tagln2
Tagln2em1(IMPC)Tcp
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
6.48×10-05
Pipox
Pipoxtm1b(EUCOMM)Wtsi
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
TCP
IMPC
8.14×10-05
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu
HOM   Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
ICS
IMPC
8.75×10-05
Cdk13
Cdk13tm1b(EUCOMM)Hmgu
HET Early adult shortened QRS complex duration QRS
Electrocardiogram (ECG)
HMGU
IMPC
9.61×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.28% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QRS complex duration (15/5296)

0.19% females (10/5250) 0.02% males (1/5238)



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