Phenotype: shortened QRS complex duration

Definition
decrease in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart
Synonyms
shortened QRS duration,  shortened QRS interval,  narrow QRS complex
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QRS complex duration

Total number of significant genotype-phenotype associations: 12

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu
HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS ICS | IMPC 1.49×10-08
Trpc5
Trpc5tm1b(KOMP)Wtsi
HOM   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS RBRC | IMPC 2.00×10-06
Fastkd5
Fastkd5em1(IMPC)J
HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS JAX | IMPC 3.63×10-06
Plscr1
Plscr1tm1b(EUCOMM)Hmgu
HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS ICS | IMPC 9.60×10-06
Mgrn1
Mgrn1em1(IMPC)Tcp
HET   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS TCP | IMPC 1.19×10-05
Gsg1l
Gsg1lem1(IMPC)Mbp
HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 3.30×10-05
Slc7a3
Slc7a3em1(IMPC)J
HEM   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS JAX | IMPC 6.09×10-05
Bbs1
Bbs1em1(IMPC)Mbp
HET Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 7.17×10-05
Brd4
Brd4tm1b(EUCOMM)Wtsi
HET Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS BCM | IMPC 7.82×10-05
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 8.74×10-05
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi
HET   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS BCM | IMPC 9.74×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.25% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QRS complex duration (11/4397)

0.11% females (5/4350) 0.07% males (3/4339)



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