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Genes Phenotypes

Phenotype: shortened QRS complex duration

Definition
decrease in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart
Synonyms
shortened QRS duration,  shortened QRS interval,  narrow QRS complex
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QRS complex duration

Total number of significant genotype-phenotype associations: 12

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ecrg4
Ecrg4tm1b(EUCOMM)Hmgu 		HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS ICS | IMPC 1.49×10-08
Trpc5
Trpc5tm1b(KOMP)Wtsi 		HOM   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS RBRC | IMPC 2.00×10-06
Fastkd5
Fastkd5em1(IMPC)J 		HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS JAX | IMPC 3.63×10-06
Plscr1
Plscr1tm1b(EUCOMM)Hmgu 		HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS ICS | IMPC 9.60×10-06
Mgrn1
Mgrn1em1(IMPC)Tcp 		HET   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS TCP | IMPC 1.19×10-05
Gsg1l
Gsg1lem1(IMPC)Mbp 		HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 3.30×10-05
Slc7a3
Slc7a3em1(IMPC)J 		HEM   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS JAX | IMPC 6.09×10-05
Bbs1
Bbs1em1(IMPC)Mbp 		HET Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 7.17×10-05
Brd4
Brd4tm1b(EUCOMM)Wtsi 		HET Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS BCM | IMPC 7.82×10-05
Clcnkb
Clcnkbem1(IMPC)Mbp 		HOM Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS UC Davis | IMPC 8.74×10-05
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi 		HET   Early adult shortened QRS complex duration Electrocardiogram (ECG) | QRS BCM | IMPC 9.74×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.25% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QRS complex duration (11/4397)

0.11% females (5/4350) 0.07% males (3/4339)



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