Phenotype: abnormal retinal blood vessel morphology

Definition
any structural anomaly of the blood vessels supplying the retina
Synonyms
abnormal retinal blood vessel structure
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal retinal blood vessel morphology

Total number of significant genotype-phenotype associations: 94

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ube2a
Ube2atm1.1(KOMP)Vlcg
HEM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 0.00
Mpdz
Mpdzem1(IMPC)J
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 6.85×10-19
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 5.91×10-15
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 8.70×10-14
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 4.70×10-13
Prkab1
Prkab1tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 6.59×10-11
Timp3
Timp3tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 1.27×10-09
Lrrc51
Lrrc51tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.62×10-09
Atxn7l3
Atxn7l3tm1.1(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 4.22×10-09
Shisal1
Shisal1em1(IMPC)Ccpcz
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure CCP-IMG | IMPC 2.91×10-08
Lss
Lsstm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.99×10-08
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 8.08×10-08
Gpr25
Gpr25em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 9.27×10-08
S1pr3
S1pr3tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.07×10-07
Cacna2d4
Cacna2d4em1(IMPC)J
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 5.24×10-07
Gjc3
Gjc3em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 8.48×10-07
Rnf10
Rnf10em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 9.26×10-07
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.25×10-06
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.53×10-06
Ptp4a1
Ptp4a1em2(IMPC)Tcp
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure TCP | IMPC 1.97×10-06
Fgfr1op
Fgfr1optm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.82×10-06
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.25×10-06
Nxn
Nxnem1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.76×10-06
Stx5a
Stx5atm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.35×10-06
Wdsub1
Wdsub1tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.41×10-06
Jtb
Jtbtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.76×10-06
Gm17359
Gm17359tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 5.03×10-06
Dhx40
Dhx40tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 5.25×10-06
Cts6
Cts6tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 5.40×10-06
5330417C22Rik
5330417C22Riktm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 5.57×10-06
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 6.22×10-06
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 7.61×10-06
Emc8
Emc8tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 7.61×10-06
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.03×10-06
Etfdh
Etfdhtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.64×10-06
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.14×10-05
Cstf3
Cstf3tm2b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.29×10-05
Msmb
Msmbtm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.43×10-05
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.50×10-05
Ifit1bl2
Ifit1bl2em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.77×10-05
Uroc1
Uroc1em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.95×10-05
Fads6
Fads6tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 2.04×10-05
Adsl
Adsltm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.10×10-05
Prdm5
Prdm5em1(IMPC)Tcp
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 2.46×10-05
Adora2b
Adora2btm1.1(KOMP)Vlcg
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 2.52×10-05
Rcn1
Rcn1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.61×10-05
Tex2
Tex2tm1.1(KOMP)Vlcg
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 2.70×10-05
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.70×10-05
Rnf38
Rnf38tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.76×10-05
Mrm2
Mrm2em1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 2.82×10-05
Pcsk1
Pcsk1tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.86×10-05
Asb2
Asb2tm2b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 2.92×10-05
Slc44a3
Slc44a3tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.97×10-05
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.00×10-05
Sdc4
Sdc4tm2b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 3.27×10-05
Lgr5
Lgr5em1(IMPC)KMPC
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure KMPC | IMPC 3.40×10-05
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 3.47×10-05
Thap1
Thap1em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 3.47×10-05
Anks1
Anks1tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.50×10-05
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.53×10-05
Rpain
Rpainem1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.18×10-05
Ifi27l2a
Ifi27l2atm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.32×10-05
Tmem151b
Tmem151btm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.46×10-05
Zfp459
Zfp459tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.49×10-05
Cib3
Cib3em1(IMPC)H
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 4.56×10-05
Rxylt1
Rxylt1em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.61×10-05
1700001O22Rik
1700001O22Rikem1(IMPC)J
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 5.10×10-05
Slc44a1
Slc44a1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 6.02×10-05
Klk5
Klk5tm2b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 6.34×10-05
Actrt3
Actrt3tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.56×10-05
Dst
Dsttm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 6.60×10-05
Epc2
Epc2tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 6.85×10-05
Dnajc15
Dnajc15tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 7.51×10-05
Flywch2
Flywch2tm4b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 7.54×10-05
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.74×10-05
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.93×10-05
Lipt1
Lipt1em1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 8.04×10-05
Nbas
Nbastm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.19×10-05
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 8.36×10-05
Nub1
Nub1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure CCP-IMG | IMPC 8.64×10-05
Pdhb
Pdhbem1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 9.10×10-05
Zfp827
Zfp827em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 9.20×10-05
Ndufa8
Ndufa8tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 9.87×10-05
Aldh1l1
Aldh1l1tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 9.95×10-05

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 The way we measure

Procedure
Eye Morphology

 Phenotype associations stats

1.75% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal retinal blood vessel morphology (82/4673)

0.49% females (23/4656) 0.93% males (43/4634)

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