Phenotype: abnormal retinal blood vessel morphology

Definition
any structural anomaly of the blood vessels supplying the retina
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal retinal blood vessel morphology

Total number of significant genotype-phenotype associations: 147

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Mpdz
Mpdzem1(IMPC)J
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 4.94×10-29
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 1.51×10-25
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 3.83×10-20
Timp3
Timp3tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 6.43×10-12
Gpr25
Gpr25em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.39×10-11
Ift172
Ift172tm2b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.83×10-11
Cacna2d4
Cacna2d4em1(IMPC)J
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure JAX | IMPC 6.60×10-11
Prkab1
Prkab1tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 9.69×10-11
Mapt
Mapttm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.49×10-10
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 7.34×10-10
Hdac1
Hdac1tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 9.47×10-10
Atxn7l3
Atxn7l3tm1.1(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.81×10-09
Ptp4a1
Ptp4a1em2(IMPC)Tcp
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure TCP | IMPC 1.23×10-08
Cib3
Cib3em1(IMPC)H
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 1.45×10-08
Hnf4a
Hnf4atm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.79×10-08
Fads6
Fads6tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 3.32×10-08
Lss
Lsstm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.76×10-08
Lrrc51
Lrrc51tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 6.85×10-08
Ehmt1
Ehmt1tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MARC | IMPC 8.16×10-08
Shisal1
Shisal1em1(IMPC)Ccpcz
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure CCP-IMG | IMPC 8.35×10-08
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.02×10-07
Pdhx
Pdhxtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.02×10-07
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.03×10-07
Elapor1
Elapor1tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 2.11×10-07
Gjc3
Gjc3em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.24×10-07
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.73×10-07
Slc44a1
Slc44a1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.67×10-07
AW549877
AW549877tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 4.89×10-07
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 5.32×10-07
Nxn
Nxnem1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 7.67×10-07
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 7.98×10-07
Ndufa8
Ndufa8tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 9.10×10-07
Tex2
Tex2tm1.1(KOMP)Vlcg
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 1.02×10-06
Stx5a
Stx5atm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.04×10-06
Uroc1
Uroc1em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.44×10-06
Tmem11
Tmem11em1(IMPC)Tcp
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 1.54×10-06
Msmb
Msmbtm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.57×10-06
Rnf10
Rnf10em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.66×10-06
Zfp827
Zfp827em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 1.67×10-06
Brd4
Brd4tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.71×10-06
1700001O22Rik
1700001O22Rikem1(IMPC)J
HOM Late adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 1.80×10-06
Vps13b
Vps13bem1(IMPC)Tcp
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 2.05×10-06
S1pr3
S1pr3tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.51×10-06
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 2.78×10-06
Fam162a
Fam162atm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.67×10-06
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.69×10-06
Pcsk1
Pcsk1tm1b(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 5.25×10-06
Ifi27l2a
Ifi27l2atm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 6.01×10-06
Cep43
Cep43tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.21×10-06
Trim31
Trim31tm2b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 8.00×10-06
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure HMGU | IMPC 1.16×10-05
Nbas
Nbastm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.33×10-05
Rcn1
Rcn1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.38×10-05
Cyb561
Cyb561tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 1.43×10-05
Ifit1bl2
Ifit1bl2em1(IMPC)Bay
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 1.49×10-05
Etfdh
Etfdhtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 1.51×10-05
Zfp459
Zfp459tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 1.78×10-05
Emc8
Emc8tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 2.14×10-05
Obp2a
Obp2atm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure ICS | IMPC 2.44×10-05
Rnf38
Rnf38tm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 2.66×10-05
Asb2
Asb2tm2b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern KMPC | IMPC 2.92×10-05
Hsf2
Hsf2tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 3.46×10-05
Cstf3
Cstf3tm2b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 3.62×10-05
Jtb
Jtbtm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.63×10-05
Gm17359
Gm17359tm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 3.99×10-05
Cr1l
Cr1ltm1b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.07×10-05
Thap1
Thap1em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 4.12×10-05
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 4.13×10-05
Fkbp1b
Fkbp1btm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 4.15×10-05
Mrm2
Mrm2em1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 4.31×10-05
Cts6
Cts6tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.55×10-05
Bmp10
Bmp10tm3b(EUCOMM)Hmgu
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 4.59×10-05
Dhx40
Dhx40tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 4.68×10-05
Bphl
Bphltm1b(EUCOMM)Hmgu
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure ICS | IMPC 5.03×10-05
Tmem151b
Tmem151btm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 5.54×10-05
Sdc4
Sdc4tm2b(KOMP)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure MRC Harwell | IMPC 6.29×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern ICS | IMPC 6.33×10-05
Shmt2
Shmt2em1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 6.54×10-05
Gbx1
Gbx1tm1b(KOMP)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern MRC Harwell | IMPC 7.08×10-05
Slc44a3
Slc44a3tm1b(EUCOMM)Wtsi
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern HMGU | IMPC 7.39×10-05
Actrt3
Actrt3tm1.1(KOMP)Vlcg
HOM Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 7.41×10-05
Polr1b
Polr1bem1(IMPC)Tcp
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern TCP | IMPC 7.41×10-05
Nxn
Nxntm1a(EUCOMM)Wtsi
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern BCM | IMPC 8.52×10-05
Adora2b
Adora2btm1.1(KOMP)Vlcg
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 9.45×10-05
Pdhb
Pdhbem1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 9.75×10-05
Lipt1
Lipt1em1(IMPC)Bay
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Structure BCM | IMPC 9.78×10-05
Ankrd52
Ankrd52em1(IMPC)J
HET Early adult abnormal retinal blood vessel morphology Eye Morphology | Retinal Blood Vessels Pattern JAX | IMPC 9.82×10-05

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 The way we measure

Procedure
Eye Morphology

 Phenotype associations stats

1.62% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal retinal blood vessel morphology (83/5138)

0.40% females (20/4955) 0.79% males (39/4959)

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