Phenotype: corneal vascularization

Definition
formation of blood vessels in the cornea, which normally lacks vessels
Synonyms
tunica cornea vascularization
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with corneal vascularization

Total number of significant genotype-phenotype associations: 27

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Spns2
Spns2tm1a(KOMP)Wtsi
HOM Early adult corneal vascularization cornea vascularisation
Slit Lamp
WTSI
EuroPhenome
4.21×10-21
Dsc2
Dsc2tm1e(KOMP)Wtsi
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
WTSI
IMPC
5.76×10-17
Spns2
Spns2tm1b(KOMP)Wtsi
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
WTSI
IMPC
5.05×10-11
Nadsyn1
Nadsyn1tm1b(KOMP)Wtsi
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
UC Davis
IMPC
1.24×10-08
Pax6
Pax6em1(IMPC)Mbp
HET Early adult corneal vascularization Corneal vascularization
Eye Morphology
UC Davis
IMPC
1.84×10-07
Ucp1
Ucp1m1H
HOM Early adult corneal vascularization Cornea vascularisation
Slit Lamp
MRC Harwell
EuroPhenome
2.54×10-07
Rfxap
Rfxapem1(IMPC)J
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
4.00×10-07
Sfrp2
Sfrp2tm1Aksh
HOM Early adult corneal vascularization Cornea vascularisation
Slit Lamp
MRC Harwell
EuroPhenome
1.58×10-06
Stk35
Stk35em1(IMPC)J
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
2.50×10-06
Nodal
Nodaltm1b(EUCOMM)Wtsi
HET   Early adult corneal vascularization Corneal vascularization
Eye Morphology
MRC Harwell
IMPC
3.22×10-06
Ubac1
Ubac1em1(IMPC)J
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
4.16×10-06
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
RBRC
IMPC
4.32×10-06
Ing5
Ing5em1(IMPC)J
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
1.53×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM   Early adult corneal vascularization cornea vascularisation
Slit Lamp
WTSI
MGP
2.56×10-05
Trpc3
Trpc3Mwk
HET Early adult corneal vascularization Cornea vascularisation
Slit Lamp
MRC Harwell
EuroPhenome
3.21×10-05
Kat14
Kat14tm1a(KOMP)Wtsi
HOM Early adult corneal vascularization cornea vascularisation
Slit Lamp
WTSI
EuroPhenome
3.52×10-05
Plekha5
Plekha5em1(IMPC)Tcp
HOM   Early adult corneal vascularization Corneal vascularization
Eye Morphology
TCP
IMPC
4.04×10-05
E2f3
E2f3tm1b(KOMP)Wtsi
HET   Late adult corneal vascularization Corneal vascularization
Eye Morphology
KMPC
IMPC
4.44×10-05
Nfil3
Nfil3tm1.1(KOMP)Vlcg
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
UC Davis
IMPC
5.08×10-05
Col6a3
Col6a3em1(IMPC)Kmpc
HOM   Early adult corneal vascularization Corneal vascularization
Eye Morphology
KMPC
IMPC
6.67×10-05
Kctd1
Kctd1em1(IMPC)J
HOM   Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
7.18×10-05
Cisd2
Cisd2tm1a(EUCOMM)Wtsi
HOM Early adult corneal vascularization Cornea vascularisation
Slit Lamp
MRC Harwell
EuroPhenome
7.60×10-05
Fancf
Fancfem1(IMPC)J
HOM Early adult corneal vascularization Corneal vascularization
Eye Morphology
JAX
IMPC
9.45×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to corneal vascularization (22/6740)

0.18% females (12/6640) 0.10% males (7/6721)

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter