Phenotype: decreased heart rate

Definition
fewer than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute
Synonyms
bradycardia,  bradyrhythmia,  reduced heart rate
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased heart rate

Total number of significant genotype-phenotype associations: 267

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Pla2g10
Pla2g10tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
6.29×10-26
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.03×10-20
Fnip1
Fnip1em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
1.10×10-20
Asap1
Asap1em1(IMPC)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
1.91×10-19
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.21×10-16
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
6.50×10-16
Mmaa
Mmaaem1(IMPC)J
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.39×10-15
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
3.52×10-14
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.49×10-14
Ndufa8
Ndufa8tm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
8.71×10-14
Dmp1
Dmp1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.07×10-13
Hcn1
Hcn1em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.89×10-13
Selenot
Selenotem1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.15×10-13
Trim55
Trim55tm2b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.63×10-13
Maged1
Maged1em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
3.46×10-13
Selenot
Selenotem1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.29×10-12
Ndufa7
Ndufa7em1(IMPC)Bay
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.04×10-12
Mmaa
Mmaaem1(IMPC)J
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
6.06×10-12
Tmem203
Tmem203em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
6.60×10-12
Dmp1
Dmp1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
7.18×10-12
Six1
Six1em1(IMPC)Mbp
HET Late adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.91×10-10
Lcorl
Lcorlem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
5.14×10-10
Psors1c2
Psors1c2em1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.06×10-09
Maged1
Maged1em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.12×10-09
Anapc7
Anapc7em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.39×10-09
Dennd5b
Dennd5bem1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
3.29×10-09
Mmab
Mmabem1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
3.70×10-09
Nadsyn1
Nadsyn1tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
5.40×10-09
Slc6a6
Slc6a6em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.12×10-09
Nav1
Nav1em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
6.73×10-09
Myo6
Myo6em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
1.01×10-08
Rab4a
Rab4atm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.51×10-08
Cpa5
Cpa5em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.24×10-08
Asap1
Asap1em1(IMPC)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.33×10-08
Pex1
Pex1tm1e.1(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
2.52×10-08
Slc6a6
Slc6a6em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
3.17×10-08
Dpp8
Dpp8em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.32×10-08
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
3.85×10-08
Trim55
Trim55tm2b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.89×10-08
Hipk3
Hipk3tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.49×10-08
Oplah
Oplahtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
HMGU
IMPC
5.09×10-08
Hcn1
Hcn1em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
5.12×10-08
Ctsa
Ctsatm2b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
8.37×10-08
Cap2
Cap2tm1b(EUCOMM)Wtsi
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
8.90×10-08
Tmem203
Tmem203em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.05×10-07
Zdhhc22
Zdhhc22em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.09×10-07
Six1
Six1em1(IMPC)Mbp
HET Late adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.14×10-07
Mindy2
Mindy2em1(IMPC)H
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.23×10-07
Mindy2
Mindy2em1(IMPC)H
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.37×10-07
Myo6
Myo6em1(IMPC)Tcp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
1.39×10-07
Try10
Try10em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.47×10-07
Maged1
Maged1em1(IMPC)Mbp
HEM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.78×10-07
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.81×10-07
Zbed6
Zbed6em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.82×10-07
Lamtor3
Lamtor3em1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
1.85×10-07
Zbed6
Zbed6em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.93×10-07
Slfn1
Slfn1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.11×10-07
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.28×10-07
Topors
Toporsem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.29×10-07
Spa17
Spa17em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.33×10-07
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
2.46×10-07
Hcrt
Hcrttm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
2.76×10-07
Cpa5
Cpa5em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.80×10-07
Anapc7
Anapc7em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.82×10-07
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.89×10-07
Spa17
Spa17em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.01×10-07
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
3.34×10-07
Smo
Smotm1b(KOMP)Wtsi
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.51×10-07
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
4.13×10-07
Ndufa7
Ndufa7em1(IMPC)Bay
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
4.33×10-07
Smo
Smotm1b(KOMP)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
6.13×10-07
Wars1
Wars1tm1b(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
6.14×10-07
Hells
Hellstm1b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Echo
HMGU
IMPC
6.42×10-07
Try10
Try10em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
6.55×10-07
Nadsyn1
Nadsyn1tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.66×10-07
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
7.45×10-07
Hipk3
Hipk3tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
7.94×10-07
Lmtk2
Lmtk2em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
9.19×10-07
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
BCM
IMPC
1.01×10-06
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.02×10-06
Ndufa6
Ndufa6em1(IMPC)Bay
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
1.05×10-06
Gabre
Gabreem1(IMPC)H
HEM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.05×10-06
Nav1
Nav1em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.15×10-06
Fam118a
Fam118aem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.15×10-06
Smarcc2
Smarcc2em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.16×10-06
Maged1
Maged1em1(IMPC)Mbp
HEM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.17×10-06
Scoc
Scocem1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.20×10-06
Dennd5b
Dennd5bem1(IMPC)Tcp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
1.44×10-06
Smarcc2
Smarcc2em1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.46×10-06
Kcna7
Kcna7em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.81×10-06
Slfn1
Slfn1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
1.85×10-06
Psors1c2
Psors1c2em1(IMPC)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.13×10-06
Rab4a
Rab4atm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.25×10-06
Tat
Tatem1(IMPC)J
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.27×10-06
Dpp8
Dpp8em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.34×10-06
Ctsa
Ctsatm2b(EUCOMM)Hmgu
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.45×10-06
Gbp2
Gbp2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
2.54×10-06
Nutf2
Nutf2tm1b(KOMP)Mbp
HET Early adult decreased heart rate HR
Echo
HMGU
IMPC
2.89×10-06
Ubl7
Ubl7em1(IMPC)Tcp
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
2.90×10-06
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
2.91×10-06
Zfp541
Zfp541em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.95×10-06
Wsb2
Wsb2tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Echo
HMGU
IMPC
3.16×10-06
Efcab14
Efcab14tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Echo
BCM
IMPC
3.47×10-06
Impact
Impactem1(IMPC)Ccpcz
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
CCP-IMG
IMPC
3.63×10-06
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.80×10-06
Enpp1
Enpp1em1(IMPC)Ccpcz
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
CCP-IMG
IMPC
3.95×10-06
Kcna7
Kcna7em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.30×10-06
Insig2
Insig2em1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.61×10-06
Pla2g10
Pla2g10tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.91×10-06
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
5.55×10-06
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
5.76×10-06
Sfswap
Sfswapem1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.25×10-06
Gabra2
Gabra2em1(IMPC)H
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
6.65×10-06
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
6.84×10-06
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
7.24×10-06
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
7.59×10-06
Il18r1
Il18r1em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
7.85×10-06
Chmp2b
Chmp2bem1(IMPC)Mbp
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
8.10×10-06
Pak2
Pak2em1(IMPC)H
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
8.48×10-06
Dgkb
Dgkbem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
8.77×10-06
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
9.12×10-06
Got1
Got1tm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.29×10-06
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
9.44×10-06
Spg11
Spg11em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.77×10-06
Tmem62
Tmem62em1(IMPC)Ccpcz
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
9.80×10-06
Btnl4
Btnl4em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
9.88×10-06
Lamtor3
Lamtor3em1(IMPC)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
1.00×10-05
Ptpn18
Ptpn18em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.06×10-05
Fkbp4
Fkbp4em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.06×10-05
Efhb
Efhbem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.10×10-05
Pygm
Pygmem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.12×10-05
Obp2b
Obp2bem1(IMPC)Kmpc
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
KMPC
IMPC
1.15×10-05
Zfp541
Zfp541em1(IMPC)J
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.17×10-05
Pdgfc
Pdgfctm1b(EUCOMM)Hmgu
HET   Late adult decreased heart rate HR
Echo
HMGU
IMPC
1.22×10-05
P3h1
P3h1tm1b(EUCOMM)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.25×10-05
Il33
Il33tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
1.26×10-05
Gabra2
Gabra2em1(IMPC)H
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.29×10-05
Rfc5
Rfc5em1(IMPC)J
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.36×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.36×10-05
Topors
Toporsem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.36×10-05
Scoc
Scocem1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.40×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.45×10-05
Tnip1
Tnip1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
1.50×10-05
Mmp13
Mmp13em1(IMPC)Ccpcz
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
CCP-IMG
IMPC
1.50×10-05
P4ha3
P4ha3em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.54×10-05
Lcorl
Lcorlem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.65×10-05
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
1.67×10-05
Agpat1
Agpat1tm1.1(KOMP)Vlcg
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.68×10-05
Atp1a1
Atp1a1em1(IMPC)Ccpcz
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
CCP-IMG
IMPC
1.84×10-05
Brd3
Brd3em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
1.95×10-05
Enpp1
Enpp1em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
CCP-IMG
IMPC
1.97×10-05
Rfc5
Rfc5em1(IMPC)J
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
1.99×10-05
Scarb2
Scarb2em2(IMPC)Tcp
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
2.11×10-05
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
2.13×10-05
Poli
Politm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
2.31×10-05
Ndufa6
Ndufa6em1(IMPC)Bay
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
2.33×10-05
Asphd1
Asphd1em1(IMPC)Ccpcz
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
2.34×10-05
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.39×10-05
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
2.42×10-05
Prss55
Prss55em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
2.45×10-05
Fkbp4
Fkbp4em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.51×10-05
Ubap2l
Ubap2lem1(IMPC)Bay
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
2.53×10-05
Sfswap
Sfswapem1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.58×10-05
Ubl7
Ubl7em1(IMPC)Tcp
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
TCP
IMPC
2.60×10-05
Arl5a
Arl5aem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.68×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
2.73×10-05
Tmem60
Tmem60em1(IMPC)Ccpcz
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
CCP-IMG
IMPC
2.74×10-05
Arv1
Arv1em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.80×10-05
Arv1
Arv1em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.85×10-05
Lep
Leptm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
2.89×10-05
Atp2b3
Atp2b3em1(IMPC)J
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
2.93×10-05
Spty2d1
Spty2d1em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
2.95×10-05
Arl5a
Arl5aem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.00×10-05
Cand1
Cand1em1(IMPC)Mbp
HET Late adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
3.02×10-05
Ccdc28a
Ccdc28atm3b(EUCOMM)Wtsi
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.16×10-05
Tat
Tatem1(IMPC)J
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.43×10-05
Mmp13
Mmp13em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
CCP-IMG
IMPC
3.61×10-05
Ogn
Ogntm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.62×10-05
Tpgs2
Tpgs2tm1.1(KOMP)Vlcg
HOM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.67×10-05
Tex2
Tex2em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
3.69×10-05
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.70×10-05
Tex21
Tex21em1(IMPC)J
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
3.72×10-05
Ehhadh
Ehhadhtm1b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
3.82×10-05
Il33
Il33tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
3.95×10-05
Sppl3
Sppl3em1(IMPC)Bay
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
BCM
IMPC
3.99×10-05
Hcrt
Hcrttm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
4.00×10-05
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
4.13×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
4.17×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.42×10-05
Bmp6
Bmp6em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
4.42×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.45×10-05
Dhx9
Dhx9tm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart rate HR
Echo
HMGU
IMPC
4.52×10-05
Cox7a2l
Cox7a2lem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.56×10-05
Chmp2b
Chmp2bem1(IMPC)Mbp
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
4.68×10-05
Rnf166
Rnf166em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.71×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
4.71×10-05
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
4.79×10-05
Eif3k
Eif3kem1(IMPC)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.89×10-05
Golt1b
Golt1btm1b(EUCOMM)Wtsi
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
4.98×10-05
Spg11
Spg11em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
5.16×10-05
Ly6g6f
Ly6g6fem1(IMPC)Hmgu
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
5.16×10-05
Dgkb
Dgkbem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
5.76×10-05
1700030J22Rik
1700030J22Rikem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.02×10-05
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
6.09×10-05
Tg
Tgem1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.18×10-05
Dcps
Dcpstm1b(EUCOMM)Hmgu
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
6.25×10-05
Spock1
Spock1em1(IMPC)H
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
6.29×10-05
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
6.29×10-05
Ist1
Ist1em1(IMPC)J
HET Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
6.47×10-05
Spock1
Spock1em1(IMPC)H
HOM   Early adult decreased heart rate HR
Electrocardiogram (ECG)
MRC Harwell
IMPC
6.52×10-05
Tyro3
Tyro3em1(IMPC)Ccpcz
HOM   Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
6.78×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
6.78×10-05
Snx29
Snx29tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate HR
Echo
ICS
IMPC
6.83×10-05
Lmtk2
Lmtk2em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
6.89×10-05
Il18r1
Il18r1em1(IMPC)Mbp
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
UC Davis
IMPC
7.10×10-05
Tor1a
Tor1aem1(IMPC)H
HET   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
7.19×10-05
Exosc1
Exosc1em1(IMPC)J
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
7.32×10-05
Tex21
Tex21em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
7.59×10-05
Zfp593
Zfp593em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
7.64×10-05
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
HMGU
IMPC
7.81×10-05
Clock
Clockem1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Echo
CCP-IMG
IMPC
7.88×10-05
Arrdc2
Arrdc2tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
7.92×10-05
Rest
Resttm2b(EUCOMM)Wtsi
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
HMGU
IMPC
8.19×10-05
Ubap2l
Ubap2lem1(IMPC)Bay
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
BCM
IMPC
8.49×10-05
Smpdl3a
Smpdl3aem1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
8.50×10-05
Ccdc28a
Ccdc28atm3b(EUCOMM)Wtsi
HOM Late adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
8.84×10-05
Tox
Toxtm1b(KOMP)Wtsi
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
8.87×10-05
Fam118a
Fam118aem1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
8.95×10-05
Dnajc13
Dnajc13em1(IMPC)J
HET   Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.01×10-05
Hsf5
Hsf5em1(IMPC)J
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
JAX
IMPC
9.04×10-05
Ptpn18
Ptpn18em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.07×10-05
Pcm1
Pcm1em1(IMPC)Tcp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
TCP
IMPC
9.07×10-05
Ist1
Ist1em1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.13×10-05
Rnd2
Rnd2em1(IMPC)Mbp
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
UC Davis
IMPC
9.21×10-05
Tbcc
Tbccem1(IMPC)J
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.41×10-05
Spock1
Spock1em1(IMPC)H
HOM   Late adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.47×10-05
Blcap
Blcapem1(IMPC)J
HOM   Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.54×10-05
Tex2
Tex2em1(IMPC)J
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
JAX
IMPC
9.56×10-05
Usp38
Usp38tm1b(EUCOMM)Hmgu
HOM Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.60×10-05
Gcsh
Gcshem1(IMPC)H
HET Early adult prolonged RR interval RR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.66×10-05
Tmem60
Tmem60em1(IMPC)Ccpcz
HOM Early adult decreased heart rate HR
Electrocardiogram (ECG)
CCP-IMG
IMPC
9.82×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

2.34% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart rate (156/6659)

1.03% females (69/6700) 1.26% males (82/6523)

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