Phenotype: abnormal heart weight

Definition
anomaly in the average weight of the heart compared to controls
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal heart weight

Total number of significant genotype-phenotype associations: 309

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
0.00
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.23×10-42
Mybpc3
Mybpc3tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
4.78×10-27
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
3.30×10-23
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
1.01×10-22
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
3.02×10-19
Fsd2
Fsd2em1(IMPC)Mbp
HOM Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.30×10-14
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
1.15×10-13
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
3.00×10-13
Map7d1
Map7d1em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.36×10-12
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.02×10-12
Pnma3
Pnma3em1(IMPC)Rbrc
HOM   Late adult abnormal heart weight Heart weight
Heart Weight
RBRC
IMPC
2.93×10-12
Gnas
Gnastm1Jop
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
7.03×10-12
Rab19
Rab19tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
4.48×10-11
Kctd1
Kctd1em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
8.40×10-11
Pdcd6ip
Pdcd6ipem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
9.31×10-11
Hsf5
Hsf5em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.36×10-10
Tmem248
Tmem248tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.57×10-10
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
4.19×10-10
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.39×10-10
Camk1d
Camk1dem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
4.78×10-10
Taco1
Taco1em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.63×10-10
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.99×10-10
Tmem203
Tmem203em1(IMPC)H
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
7.49×10-10
Yipf6
Yipf6em1(IMPC)Mbp
HOM   Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
8.11×10-10
Lcn2
Lcn2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.06×10-09
Srcin1
Srcin1tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.15×10-09
Ppp1r12b
Ppp1r12bem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.63×10-09
Ptp4a3
Ptp4a3em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.01×10-09
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.76×10-09
Kcng2
Kcng2em1(IMPC)Bay
HOM Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
3.80×10-09
Rbm22
Rbm22em1(IMPC)Mbp
HET Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
4.45×10-09
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
5.81×10-09
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.83×10-09
Stx7
Stx7em1(IMPC)Rbrc
HOM Late adult abnormal heart weight Heart weight
Heart Weight
RBRC
IMPC
7.11×10-09
Rab28
Rab28em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
7.45×10-09
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
8.00×10-09
Tox3
Tox3tm1b(KOMP)Mbp
HET Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
8.06×10-09
Ttc39a
Ttc39atm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
1.01×10-08
Trappc2l
Trappc2lem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.27×10-08
Pdp1
Pdp1em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.77×10-08
Dynlrb2
Dynlrb2tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
1.92×10-08
Mylk4
Mylk4em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
2.44×10-08
Stx11
Stx11em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.61×10-08
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
2.82×10-08
Pax6
Pax6em1(IMPC)Mbp
HET Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
3.51×10-08
Eid2
Eid2em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
3.53×10-08
Ltv1
Ltv1em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.23×10-08
Gopc
Gopctm1e.1(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.26×10-08
Hrh4
Hrh4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
4.97×10-08
Ide
Idetm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
6.68×10-08
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
6.73×10-08
Zfp593
Zfp593em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
7.58×10-08
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
BCM
IMPC
7.98×10-08
Asic1
Asic1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.19×10-07
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
1.19×10-07
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Heart Weight
HMGU
IMPC
1.20×10-07
Gpld1
Gpld1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.24×10-07
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
1.54×10-07
Fndc3a
Fndc3aem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
1.54×10-07
Lrrc41
Lrrc41em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.75×10-07
Ywhaz
Ywhaztm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.83×10-07
Zfp202
Zfp202em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.93×10-07
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.22×10-07
2210408I21Rik
2210408I21Riktm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.45×10-07
Rap1gap2
Rap1gap2tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
3.12×10-07
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM   Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
3.28×10-07
Lrrtm1
Lrrtm1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.54×10-07
Opn3
Opn3em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
3.65×10-07
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
3.89×10-07
Elmod3
Elmod3em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.26×10-07
Rnf14
Rnf14em1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart weight
Heart Weight
CCP-IMG
IMPC
4.61×10-07
G2e3
G2e3em1(IMPC)Tcp
HOM Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
4.62×10-07
Lama4
Lama4tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.74×10-07
Wdr47
Wdr47tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
4.92×10-07
Sbsn
Sbsnem1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart weight
Heart Weight
CCP-IMG
IMPC
5.33×10-07
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
5.44×10-07
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.68×10-07
Naa10
Naa10em1(IMPC)Mbp
HEM   Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.76×10-07
Mpv17
Mpv17em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
5.87×10-07
Steap3
Steap3tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.10×10-07
Sik1
Sik1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.88×10-07
Dppa1
Dppa1tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
6.88×10-07
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
7.02×10-07
Spns1
Spns1tm1e(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
1.01×10-06
2610507B11Rik
2610507B11Rikem1(IMPC)J
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.29×10-06
Rpa1
Rpa1tm1b(KOMP)Wtsi
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.30×10-06
Nos3
Nos3em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.47×10-06
Siglec1
Siglec1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.58×10-06
Mmp2
Mmp2em1(IMPC)Mbp
HOM   Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
1.58×10-06
Kpna4
Kpna4em1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.60×10-06
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
1.60×10-06
Hcn1
Hcn1em1(IMPC)H
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.72×10-06
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.21×10-06
Stox2
Stox2tm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.33×10-06
P2rx4
P2rx4tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.54×10-06
Srek1
Srek1em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
2.67×10-06
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
2.84×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.84×10-06
Rnf24
Rnf24em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
2.89×10-06
Ythdc2
Ythdc2em1(IMPC)Bay
HOM Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
2.94×10-06
Xpo1
Xpo1em1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.24×10-06
Rhbdf2
Rhbdf2Rhbdf2
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
3.25×10-06
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
3.36×10-06
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
3.38×10-06
Vsig4
Vsig4tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.49×10-06
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
MARC
IMPC
3.59×10-06
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
3.94×10-06
Afg1l
Afg1lem1(IMPC)KMPC
HOM Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
3.97×10-06
Nans
Nansem1(IMPC)Tcp
HET Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
4.18×10-06
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
4.21×10-06
Kash5
Kash5em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.51×10-06
Shfl
Shfltm1.1(KOMP)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.51×10-06
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
5.24×10-06
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
5.42×10-06
Fbxo43
Fbxo43em1(IMPC)Marc
HOM Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
5.47×10-06
Zfp462
Zfp462em1(IMPC)Tcp
HET Early adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
5.53×10-06
Cd36
Cd36em1(IMPC)Mbp
HOM Late adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.70×10-06
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
5.70×10-06
Ipo4
Ipo4em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
5.73×10-06
Plaat3
Plaat3em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
5.85×10-06
Tbl1xr1
Tbl1xr1tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
5.87×10-06
Acsl4
Acsl4tm1a(EUCOMM)Wtsi
HET   Early adult decreased heart weight Heart weight
Heart Dissection
WTSI
MGP
5.95×10-06
Dcp2
Dcp2tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
6.00×10-06
Tmem86a
Tmem86atm1b(KOMP)Mbp
HOM Late adult decreased heart weight Heart weight
Heart Weight
KMPC
IMPC
6.07×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.08×10-06
Gsto2
Gsto2tm2a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
6.10×10-06
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
6.20×10-06
Mbtd1
Mbtd1tm2a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
6.62×10-06
Clrn2
Clrn2em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
7.23×10-06
Gda
Gdatm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
7.39×10-06
Pebp1
Pebp1em1(IMPC)Tcp
HOM   Late adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
7.82×10-06
Cbarp
Cbarptm2e.1(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
7.93×10-06
Dnm1l
Dnm1ltm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
8.21×10-06
Prf1
Prf1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
8.28×10-06
Rasa1
Rasa1tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
8.45×10-06
Erap1
Erap1tm2b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
8.46×10-06
Gorasp1
Gorasp1tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
8.56×10-06
Slc25a21
Slc25a21tm1d(KOMP)Wtsi
HOM   Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
9.11×10-06
Acvr1c
Acvr1ctm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.14×10-06
Grin2d
Grin2dtm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
9.24×10-06
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
9.34×10-06
Secisbp2l
Secisbp2lem1(IMPC)J
HOM Late adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
9.35×10-06
Herc1
Herc1em3(IMPC)Wtsi
HOM   Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
9.77×10-06
1700008P02Rik
1700008P02Rikem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
9.84×10-06
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
1.02×10-05
Atrn
Atrntm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.06×10-05
Arhgap11a
Arhgap11aem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.13×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
1.23×10-05
Ap1g1
Ap1g1tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.26×10-05
Ube2u
Ube2utm1e.1(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.33×10-05
Kcnt2
Kcnt2em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
1.45×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
1.45×10-05
Gimap8
Gimap8tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.48×10-05
Dnd1
Dnd1em1(IMPC)Bay
HOM Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
1.54×10-05
Atg2b
Atg2bem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.60×10-05
Mpdz
Mpdzem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
1.60×10-05
Exd1
Exd1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
1.61×10-05
Il17rd
Il17rdtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.63×10-05
Thsd4
Thsd4em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
1.64×10-05
Arhgef6
Arhgef6tm2e.1(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.69×10-05
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
1.71×10-05
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart weight
Heart Weight
CCP-IMG
IMPC
1.72×10-05
Kctd15
Kctd15tm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
1.85×10-05
Cdk12
Cdk12em1(IMPC)Tcp
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.85×10-05
Krt26
Krt26em1(IMPC)KMPC
HOM Late adult decreased heart weight Heart weight
Heart Weight
KMPC
IMPC
1.88×10-05
Cln6
Cln6tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
1.96×10-05
Arsj
Arsjem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.03×10-05
Tex45
Tex45tm3b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
2.07×10-05
Shisa6
Shisa6em1(IMPC)Tcp
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.11×10-05
Slc25a25
Slc25a25tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.12×10-05
Hivep1
Hivep1tm1(KOMP)Mbp
HET   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.13×10-05
Taco1
Taco1em1(IMPC)J
HOM   Late adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.14×10-05
Dcaf10
Dcaf10tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
2.17×10-05
Zc3hc1
Zc3hc1tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
2.18×10-05
Tpgs2
Tpgs2tm1.1(KOMP)Vlcg
HOM Late adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
2.26×10-05
Ifitm1
Ifitm1not yet assigned
HOM Early adult decreased heart weight Heart weight
Heart weight/tibia length
HMGU
EuroPhenome
2.37×10-05
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.41×10-05
Dram1
Dram1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.46×10-05
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.51×10-05
Slc16a2
Slc16a2tm1a(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
2.51×10-05
Tle4
Tle4em1(IMPC)Mbp
HOM   Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.53×10-05
Hddc2
Hddc2em1(IMPC)H
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.61×10-05
Rfxap
Rfxapem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
2.65×10-05
Eng
Engem1(IMPC)Mbp
HET   Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.67×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
2.68×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
2.72×10-05
Myc
Mycem1(IMPC)KMPC
HET   Early adult decreased heart weight Heart weight
Heart Weight
KMPC
IMPC
2.76×10-05
Ptgis
Ptgisem1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
2.82×10-05
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
2.84×10-05
Tenm4
Tenm4em1(IMPC)Tcp
HOM Late adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
2.93×10-05
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
2.93×10-05
Six1
Six1em1(IMPC)Mbp
HET Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
2.96×10-05
Coq2
Coq2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
3.05×10-05
Vwa1
Vwa1tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
3.07×10-05
Egr4
Egr4tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
3.28×10-05
Neurl4
Neurl4em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
3.38×10-05
Dpp8
Dpp8em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
3.39×10-05
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
3.40×10-05
Cd36
Cd36em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.43×10-05
Nox4
Nox4tm1.1Hwsc
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
HMGU
EuroPhenome
3.46×10-05
Adgrf3
Adgrf3em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
3.47×10-05
Mplkip
Mplkiptm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
3.50×10-05
Bbox1
Bbox1tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
3.60×10-05
Tnks
Tnksem1(IMPC)Hmgu
HOM   Early adult increased heart weight Heart weight
Heart Weight
HMGU
IMPC
3.81×10-05
Otop3
Otop3tm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
3.89×10-05
Dap
Daptm1a(KOMP)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
3.97×10-05
Nlgn3
Nlgn3em1(IMPC)Rbrc
HEM   Late adult abnormal heart weight Heart weight
Heart Weight
RBRC
IMPC
3.99×10-05
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM Early adult decreased heart weight Heart weight
Heart Weight
MARC
IMPC
4.00×10-05
Kctd13
Kctd13em2(IMPC)Ics
HOM Early adult decreased heart weight Heart weight
Heart Weight
ICS
IMPC
4.01×10-05
Otogl
Otoglem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.07×10-05
Asic2
Asic2em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
4.22×10-05
Fundc1
Fundc1tm1c(KOMP)Wtsi
HEM   Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.25×10-05
Phyh
Phyhtm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
4.27×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Heart Weight
RBRC
IMPC
4.30×10-05
Slc25a42
Slc25a42em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.31×10-05
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
4.48×10-05
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.48×10-05
Pcyox1l
Pcyox1lem1(IMPC)J
HOM   Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.52×10-05
4932438A13Rik
4932438A13Riktm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
4.53×10-05
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
4.54×10-05
Gmnn
Gmnntm1a(KOMP)Wtsi
HET   Early adult decreased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
4.56×10-05
Gm648
Gm648tm1e(KOMP)Wtsi
HEM   Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
4.61×10-05
Cntnap5a
Cntnap5aem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
4.82×10-05
Setd2
Setd2tm1b(NCOM)Mfgc
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
5.27×10-05
Mturn
Mturntm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.28×10-05
Nog
Nogem1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
5.32×10-05
Plpp3
Plpp3tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
5.34×10-05
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
5.63×10-05
Cops7a
Cops7atm1b(KOMP)Mbp
HOM   Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
5.67×10-05
Gpr61
Gpr61em1(IMPC)Bay
HOM   Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
5.85×10-05
2510009E07Rik
2510009E07Rikem1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart weight
Heart Weight
CCP-IMG
IMPC
5.91×10-05
Dlg2
Dlg2tm1Dsb
HOM   Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
5.94×10-05
Lmna
Lmnatm1b(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
5.95×10-05
Rcc2
Rcc2tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
5.96×10-05
Pcnx4
Pcnx4em1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
6.05×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
6.19×10-05
Usp24
Usp24tm1a(KOMP)Wtsi
HOM Early adult decreased heart weight Heart weight
Heart Weight
WTSI
IMPC
6.24×10-05
Btg1
Btg1em1(IMPC)Mbp
HOM   Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.24×10-05
Arhgap33
Arhgap33tm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Weight
BCM
IMPC
6.25×10-05
Specc1l
Specc1lem1(IMPC)J
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.35×10-05
Tmem163
Tmem163em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.37×10-05
Vsir
Vsirtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.48×10-05
Rab39b
Rab39bem1(IMPC)Tcp
HEM   Late adult decreased heart weight Heart weight
Heart Weight
TCP
IMPC
6.59×10-05
F10
F10tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
6.61×10-05
Lox
Loxem1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
6.68×10-05
Ptpn5
Ptpn5tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
JAX
IMPC
6.71×10-05
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Organ Weight
UC Davis
IMPC
6.75×10-05
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart weight
Heart Weight
ICS
IMPC
6.78×10-05
Hdac3
Hdac3tm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
6.81×10-05
Ncor2
Ncor2Ncor2
HET Early adult decreased heart weight Heart weight
Heart weight/tibia length
ICS
EuroPhenome
6.99×10-05
Cacna1c
Cacna1cem1(IMPC)Mbp
HET Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
7.33×10-05
Rtn4r
Rtn4rtm1b(KOMP)Wtsi
HOM   Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
7.52×10-05
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
WTSI
EuroPhenome
7.73×10-05
Timp4
Timp4em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
7.76×10-05
Ankrd12
Ankrd12tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
8.32×10-05
Erp44
Erp44tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
8.38×10-05
Zmynd8
Zmynd8tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight
Heart Dissection
WTSI
MGP
8.43×10-05
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM   Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
8.49×10-05
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Organ Weight
UC Davis
IMPC
8.51×10-05
Wdr81
Wdr81em1(IMPC)J
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
8.51×10-05
Phkb
Phkbem1(IMPC)J
HOM   Late adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
8.58×10-05
Heca
Hecaem1(IMPC)J
HOM Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
8.62×10-05
Pawr
Pawrtm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
8.66×10-05
Zfp84
Zfp84tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
8.81×10-05
Phf11a
Phf11atm1b(NCOM)Mfgc
HET Early adult decreased heart weight Heart weight
Heart Weight
MARC
IMPC
9.02×10-05
Idh1
Idh1tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Weight
TCP
IMPC
9.11×10-05
Spred1
Spred1em1(IMPC)Ccpcz
HOM   Early adult increased heart weight Heart weight
Heart Weight
CCP-IMG
IMPC
9.11×10-05
Pld4
Pld4em1(IMPC)Mbp
HOM   Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
9.12×10-05
Pon3
Pon3tm1b(KOMP)Wtsi
HOM Late adult increased heart weight Heart weight
Heart Weight
KMPC
IMPC
9.29×10-05
Mrps22
Mrps22tm1.1(KOMP)Vlcg
HET Early adult decreased heart weight Heart weight
Heart Weight
JAX
IMPC
9.30×10-05
Crabp2
Crabp2em1(IMPC)Mbp
HOM Early adult increased heart weight Heart weight
Heart Weight
UC Davis
IMPC
9.40×10-05
Il31ra
Il31ratm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
9.49×10-05
Asns
Asnstm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart weight/tibia length
MRC Harwell
EuroPhenome
9.53×10-05
Synj2
Synj2tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight
Heart Dissection
WTSI
EuroPhenome
9.53×10-05
Polb
Polbtm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart weight
Heart Weight
WTSI
IMPC
9.66×10-05
Gria1
Gria1em1(IMPC)H
HOM Late adult decreased heart weight Heart weight
Organ Weight
MRC Harwell
IMPC
9.87×10-05
Prl7b1
Prl7b1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart weight
Heart Weight
UC Davis
IMPC
9.89×10-05
Etaa1
Etaa1em1(IMPC)Marc
HOM   Early adult increased heart weight Heart weight
Heart Weight
MARC
IMPC
9.91×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

4.48% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal heart weight (276/6155)

0.92% females (55/6005) 3.35% males (201/6001)

Select a parameter    



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