Phenotype: abnormal heart weight

Definition
anomaly in the average weight of the heart compared to controls
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal heart weight

Total number of significant genotype-phenotype associations: 295

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 0.00
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.11×10-42
Mybpc3
Mybpc3tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 4.78×10-27
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.71×10-23
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 1.01×10-22
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 8.61×10-19
Fsd2
Fsd2em1(IMPC)Mbp
HOM Late adult increased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.93×10-14
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 2.83×10-14
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 3.00×10-13
Map7d1
Map7d1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.60×10-13
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.67×10-12
Pnma3
Pnma3em1(IMPC)Rbrc
HOM   Late adult abnormal heart weight Heart Weight | Heart weight RBRC | IMPC 2.93×10-12
Gnas
Gnastm1Jop
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 7.03×10-12
Rab19
Rab19tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 4.48×10-11
Kctd1
Kctd1em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.89×10-11
Tmem248
Tmem248tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.78×10-10
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.73×10-10
Ptp4a3
Ptp4a3em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.97×10-10
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 5.49×10-10
Taco1
Taco1em1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 5.70×10-10
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.20×10-10
Tmem203
Tmem203em1(IMPC)H
HOM   Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.52×10-10
Pdcd6ip
Pdcd6ipem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 6.60×10-10
Camk1d
Camk1dem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.37×10-10
Yipf6
Yipf6em1(IMPC)Mbp
HOM   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.45×10-09
Lcn2
Lcn2tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.56×10-09
Srcin1
Srcin1tm1.1(KOMP)Vlcg
HET Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.67×10-09
Ppp1r12b
Ppp1r12bem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.78×10-09
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.63×10-09
Lrig1
Lrig1tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 3.71×10-09
Kcng2
Kcng2em1(IMPC)Bay
HOM Early adult increased heart weight Heart Weight | Heart weight BCM | IMPC 4.84×10-09
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 5.81×10-09
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 6.85×10-09
Stx7
Stx7em1(IMPC)Rbrc
HOM Late adult abnormal heart weight Heart Weight | Heart weight RBRC | IMPC 7.11×10-09
Rab28
Rab28em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 7.52×10-09
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 8.00×10-09
Tox3
Tox3tm1b(KOMP)Mbp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 8.06×10-09
Ttc39a
Ttc39atm1b(KOMP)Mbp
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 1.01×10-08
Trappc2l
Trappc2lem1(IMPC)Mbp
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.05×10-08
Pdp1
Pdp1em1(IMPC)Mbp
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.66×10-08
Dynlrb2
Dynlrb2tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 1.92×10-08
Stx11
Stx11em1(IMPC)Mbp
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.47×10-08
Mylk4
Mylk4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.53×10-08
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.82×10-08
Eid2
Eid2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.93×10-08
Ltv1
Ltv1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.57×10-08
Gopc
Gopctm1e.1(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.41×10-08
Hrh4
Hrh4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 4.97×10-08
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 6.73×10-08
Zfp593
Zfp593em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 7.85×10-08
Pax6
Pax6em1(IMPC)Mbp
HET Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.30×10-08
Gpld1
Gpld1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.14×10-07
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 1.19×10-07
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight HMGU | IMPC 1.20×10-07
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart Weight | Heart weight BCM | IMPC 1.35×10-07
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 1.54×10-07
Zfp202
Zfp202em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.67×10-07
Lrrc41
Lrrc41em1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.82×10-07
Slc25a25
Slc25a25tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.95×10-07
Asic1
Asic1em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.00×10-07
Ywhaz
Ywhaztm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.10×10-07
Fndc3a
Fndc3aem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 3.02×10-07
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.11×10-07
Rap1gap2
Rap1gap2tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 3.12×10-07
Slc38a10
Slc38a10tm1a(EUCOMM)Wtsi
HOM   Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 3.28×10-07
Elmod3
Elmod3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.41×10-07
Naa10
Naa10em1(IMPC)Mbp
HEM   Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.64×10-07
2510009E07Rik
2510009E07Rikem1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 3.73×10-07
Lama4
Lama4tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.26×10-07
G2e3
G2e3em1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 4.52×10-07
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.75×10-07
Wdr47
Wdr47tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 4.97×10-07
Steap3
Steap3tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 5.10×10-07
Lrrtm1
Lrrtm1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 5.41×10-07
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart Weight | Heart weight MARC | IMPC 5.44×10-07
Mpv17
Mpv17em1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 5.93×10-07
Sik1
Sik1tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.61×10-07
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 6.73×10-07
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 6.80×10-07
Dppa1
Dppa1tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 6.88×10-07
Ide
Idetm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 7.67×10-07
Opn3
Opn3em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 7.80×10-07
Spns1
Spns1tm1e(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 1.01×10-06
Mmp2
Mmp2em1(IMPC)Mbp
HOM   Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.12×10-06
2610507B11Rik
2610507B11Rikem1(IMPC)J
HET Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.25×10-06
Hcn1
Hcn1em1(IMPC)H
HOM Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.40×10-06
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 1.60×10-06
Rpa1
Rpa1tm1b(KOMP)Wtsi
HET   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.64×10-06
Nos3
Nos3em1(IMPC)Mbp
HOM Early adult increased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.74×10-06
Siglec1
Siglec1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.80×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.98×10-06
Rnf24
Rnf24em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.33×10-06
Srek1
Srek1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.47×10-06
P2rx4
P2rx4tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.49×10-06
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.51×10-06
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.84×10-06
Xpo1
Xpo1em1(IMPC)Mbp
HET Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.85×10-06
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.99×10-06
Stox2
Stox2tm2b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 2.99×10-06
Rhbdf2
Rhbdf2Rhbdf2
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 3.25×10-06
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 3.38×10-06
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 3.59×10-06
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 3.94×10-06
Vsig4
Vsig4tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 3.96×10-06
Ythdc2
Ythdc2em1(IMPC)Bay
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 3.98×10-06
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 4.21×10-06
Sbsn
Sbsnem1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 4.26×10-06
Kash5
Kash5em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.69×10-06
Shfl
Shfltm1.1(KOMP)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.80×10-06
Nans
Nansem1(IMPC)Tcp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 5.09×10-06
Atp5b
Atp5btm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 5.21×10-06
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 5.42×10-06
Fbxo43
Fbxo43em1(IMPC)Marc
HOM Early adult increased heart weight Heart Weight | Heart weight MARC | IMPC 5.47×10-06
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.53×10-06
Acsl4
Acsl4tm1a(EUCOMM)Wtsi
HET   Early adult decreased heart weight Heart Dissection | Heart weight WTSI | MGP 5.60×10-06
Ipo4
Ipo4em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.90×10-06
Dcp2
Dcp2tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 6.00×10-06
Gsto2
Gsto2tm2a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 6.10×10-06
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.38×10-06
Clrn2
Clrn2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.49×10-06
Mbtd1
Mbtd1tm2a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 6.71×10-06
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 6.81×10-06
Tbl1xr1
Tbl1xr1tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Heart Weight | Heart weight HMGU | IMPC 6.84×10-06
Gda
Gdatm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 7.39×10-06
Nucb1
Nucb1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.01×10-06
Cidec
Cidectm1(EGFP_CreERT2)Wtsi
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 8.09×10-06
Dnm1l
Dnm1ltm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 8.21×10-06
Pebp1
Pebp1em1(IMPC)Tcp
HOM   Late adult increased heart weight Heart Weight | Heart weight TCP | IMPC 8.46×10-06
Gorasp1
Gorasp1tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 8.56×10-06
Cbarp
Cbarptm2e.1(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 8.63×10-06
Plaat3
Plaat3em1(IMPC)Tcp
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 8.73×10-06
Rasa1
Rasa1tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 8.76×10-06
Taco1
Taco1em1(IMPC)J
HOM   Late adult increased heart weight Heart Weight | Heart weight JAX | IMPC 8.86×10-06
Slc25a21
Slc25a21tm1d(KOMP)Wtsi
HOM   Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 9.11×10-06
Grin2d
Grin2dtm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 9.24×10-06
Prf1
Prf1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.76×10-06
Herc1
Herc1em3(IMPC)Wtsi
HOM   Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 9.77×10-06
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.00×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult increased heart weight Heart Weight | Heart weight KMPC | IMPC 1.01×10-05
Atp8b1
Atp8b1em1(IMPC)Tcp
HOM Late adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 1.07×10-05
Arhgap11a
Arhgap11aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.08×10-05
Acvr1c
Acvr1ctm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.11×10-05
Atrn
Atrntm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.18×10-05
Zfp462
Zfp462em1(IMPC)Tcp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 1.22×10-05
Ap1g1
Ap1g1tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.24×10-05
Erap1
Erap1tm2b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight KMPC | IMPC 1.29×10-05
Eng
Engem1(IMPC)Mbp
HET   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.34×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 1.42×10-05
Thsd4
Thsd4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.43×10-05
Ube2u
Ube2utm1e.1(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.47×10-05
Il17rd
Il17rdtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.60×10-05
Exd1
Exd1tm1b(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 1.61×10-05
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.65×10-05
Rhpn1
Rhpn1tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.66×10-05
Pawr
Pawrtm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.69×10-05
Gimap8
Gimap8tm1.1(KOMP)Vlcg
HOM   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.77×10-05
Dnd1
Dnd1em1(IMPC)Bay
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 1.77×10-05
Mpdz
Mpdzem1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.81×10-05
Kctd15
Kctd15tm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 1.85×10-05
Slit2
Slit2em1(IMPC)Mbp
HET   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.94×10-05
Hivep1
Hivep1tm1(KOMP)Mbp
HET   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.94×10-05
Atg2b
Atg2bem1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 1.96×10-05
Tex45
Tex45tm3b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 2.05×10-05
Rnf14
Rnf14em1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 2.05×10-05
Kcnt2
Kcnt2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.11×10-05
Kpna4
Kpna4em1(IMPC)J
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 2.16×10-05
Zc3hc1
Zc3hc1tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 2.21×10-05
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.31×10-05
Cdk12
Cdk12em1(IMPC)Tcp
HET Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.34×10-05
Ifitm1
Ifitm1not yet assigned
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 2.37×10-05
Cln6
Cln6tm1b(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.39×10-05
Tle4
Tle4em1(IMPC)Mbp
HOM   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.41×10-05
Shisa6
Shisa6em1(IMPC)Tcp
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.47×10-05
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.47×10-05
Hddc2
Hddc2em1(IMPC)H
HOM Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.48×10-05
Slc16a2
Slc16a2tm1a(KOMP)Wtsi
HOM   Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 2.55×10-05
Dcaf10
Dcaf10tm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 2.63×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.67×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.68×10-05
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM   Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 2.84×10-05
Arhgef6
Arhgef6tm2e.1(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 2.87×10-05
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM   Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 2.93×10-05
Ptgis
Ptgisem1(IMPC)Mbp
HOM Early adult increased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.99×10-05
Adgrf3
Adgrf3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.04×10-05
Mplkip
Mplkiptm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 3.35×10-05
Coq2
Coq2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 3.37×10-05
Krt26
Krt26em1(IMPC)KMPC
HOM Late adult decreased heart weight Heart Weight | Heart weight KMPC | IMPC 3.37×10-05
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM   Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 3.42×10-05
Nox4
Nox4tm1.1Hwsc
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 3.46×10-05
Dram1
Dram1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.53×10-05
Neurl4
Neurl4em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.68×10-05
Otop3
Otop3tm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 3.89×10-05
Fastk
Fastktm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 3.94×10-05
Dap
Daptm1a(KOMP)Mbp
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 3.97×10-05
Nlgn3
Nlgn3em1(IMPC)Rbrc
HEM   Late adult abnormal heart weight Heart Weight | Heart weight RBRC | IMPC 3.99×10-05
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 4.00×10-05
Kctd13
Kctd13em2(IMPC)Ics
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 4.01×10-05
Otogl
Otoglem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.07×10-05
Vwa1
Vwa1tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 4.12×10-05
Bbox1
Bbox1tm1b(KOMP)Wtsi
HOM   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 4.16×10-05
Egr4
Egr4tm1.1(KOMP)Vlcg
HOM   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 4.20×10-05
Fundc1
Fundc1tm1c(KOMP)Wtsi
HEM   Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 4.25×10-05
Plpp3
Plpp3tm1b(EUCOMM)Hmgu
HET Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.29×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight RBRC | IMPC 4.30×10-05
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 4.44×10-05
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 4.48×10-05
Cntnap5a
Cntnap5aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.51×10-05
Serf1
Serf1tm1a(EUCOMM)Hmgu
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 4.54×10-05
Gmnn
Gmnntm1a(KOMP)Wtsi
HET   Early adult decreased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 4.61×10-05
Nog
Nogem1(IMPC)Mbp
HET Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.61×10-05
Gm648
Gm648tm1e(KOMP)Wtsi
HEM   Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 4.61×10-05
Pcyox1l
Pcyox1lem1(IMPC)J
HOM   Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.69×10-05
4932438A13Rik
4932438A13Riktm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 5.02×10-05
Pcnx4
Pcnx4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.03×10-05
Phyh
Phyhtm1b(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 5.16×10-05
Qsox1
Qsox1em1(IMPC)KMPC
HOM Late adult increased heart weight Heart Weight | Heart weight KMPC | IMPC 5.16×10-05
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 5.19×10-05
Mturn
Mturntm1.1(KOMP)Vlcg
HOM Early adult increased heart weight Heart Weight | Heart weight UC Davis | IMPC 5.25×10-05
Cops7a
Cops7atm1b(KOMP)Mbp
HOM   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.45×10-05
S100b
S100btm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Dissection | Heart weight WTSI | MGP 5.48×10-05
Rcc2
Rcc2tm1b(EUCOMM)Wtsi
HOM   Early adult increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 5.75×10-05
Dlg2
Dlg2tm1Dsb
HOM   Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 5.94×10-05
Lmna
Lmnatm1b(EUCOMM)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 5.95×10-05
Cacna1c
Cacna1cem1(IMPC)Mbp
HET Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.19×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.19×10-05
Asic2
Asic2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.20×10-05
Tpgs2
Tpgs2tm1.1(KOMP)Vlcg
HOM Late adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.22×10-05
Usp24
Usp24tm1a(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.24×10-05
Btg1
Btg1em1(IMPC)Mbp
HOM   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.40×10-05
Tnks
Tnksem1(IMPC)Hmgu
HOM   Early adult increased heart weight Heart Weight | Heart weight HMGU | IMPC 6.40×10-05
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.40×10-05
F10
F10tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.48×10-05
Hdac3
Hdac3tm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 6.76×10-05
Kansl1
Kansl1tm1b(EUCOMM)Hmgu
HET   Early adult increased heart weight Heart Weight | Heart weight ICS | IMPC 6.78×10-05
Setd2
Setd2tm1b(NCOM)Mfgc
HOM Early adult increased heart weight Heart Weight | Heart weight TCP | IMPC 6.87×10-05
Tenm4
Tenm4em1(IMPC)Tcp
HOM Late adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 6.93×10-05
Ncor2
Ncor2Ncor2
HET Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 6.99×10-05
Arhgap33
Arhgap33tm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 7.23×10-05
Gpr61
Gpr61em1(IMPC)Bay
HOM   Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 7.24×10-05
Wdr81
Wdr81em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 7.35×10-05
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight WTSI | EuroPhenome 7.73×10-05
Heca
Hecaem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 7.83×10-05
Ubtf
Ubtfem1(IMPC)Mbp
HET   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 7.85×10-05
Crabp2
Crabp2em1(IMPC)Mbp
HOM Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 8.12×10-05
Ptpn5
Ptpn5tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight JAX | IMPC 8.30×10-05
Ankrd12
Ankrd12tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 8.32×10-05
Erp44
Erp44tm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 8.38×10-05
Ush1c
Ush1ctm1a(KOMP)Wtsi
HOM   Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 8.49×10-05
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult decreased heart weight Heart Weight | Heart weight CCP-IMG | IMPC 8.50×10-05
Tmem163
Tmem163em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.61×10-05
Zmynd8
Zmynd8tm1a(EUCOMM)Wtsi
HET Early adult increased heart weight Heart Dissection | Heart weight WTSI | MGP 8.65×10-05
Zfp84
Zfp84tm1b(KOMP)Wtsi
HOM Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 8.81×10-05
Rtn4r
Rtn4rtm1b(KOMP)Wtsi
HOM   Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.01×10-05
Phf11a
Phf11atm1b(NCOM)Mfgc
HET Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 9.02×10-05
Vsir
Vsirtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.03×10-05
Il31ra
Il31ratm1b(EUCOMM)Hmgu
HOM   Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 9.20×10-05
Slitrk2
Slitrk2em1(IMPC)Mbp
HEM   Early adult increased heart weight Organ Weight | Heart weight UC Davis | IMPC 9.49×10-05
Synj2
Synj2tm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 9.52×10-05
Asns
Asnstm1a(EUCOMM)Wtsi
HOM Early adult increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 9.53×10-05
Trf
Trfem1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.58×10-05
Polb
Polbtm1a(KOMP)Wtsi
HET Early adult increased heart weight Heart Weight | Heart weight WTSI | IMPC 9.66×10-05
Timp4
Timp4em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 9.73×10-05
Etaa1
Etaa1em1(IMPC)Marc
HOM   Early adult increased heart weight Heart Weight | Heart weight MARC | IMPC 9.91×10-05
Mrps22
Mrps22tm1.1(KOMP)Vlcg
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.93×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

4.49% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal heart weight (262/5839)

0.96% females (55/5715) 3.29% males (188/5708)

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