Phenotype: abnormal QT variability

Definition
anomaly in the index of beat-to-beat QT interval fluctuations (temporal QT interval variability), normally expressed as a unitless negative number reflecting beat-to-beat changes in ventricular repolarization; an increased, positive QTVI number indicates significant repolarization abnormalities
Synonyms
abnormal QTVI
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal QT variability

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Ucp1
Ucp1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
HMGU
IMPC
1.32×10-06
Cecr2
Cecr2tm2b(EUCOMM)Hmgu
HET Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
TCP
IMPC
1.31×10-05
Rnf208
Rnf208em1(IMPC)Ccpcz
HOM   Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
CCP-IMG
IMPC
3.50×10-05
Phactr4
Phactr4em1(IMPC)Hmgu
HET Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
HMGU
IMPC
6.23×10-05
Scarb2
Scarb2em2(IMPC)Tcp
HOM   Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
TCP
IMPC
8.13×10-05
Slc13a5
Slc13a5tm1b(EUCOMM)Hmgu
HOM   Early adult abnormal QT variability QT Dispersion
Electrocardiogram (ECG)
HMGU
IMPC
9.25×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.61% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal QT variability (6/980)

0.31% females (3/972) 0.00% males (0/972)



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