Phenotype: shortened QT interval

Definition
decrease in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
Synonyms
decreased QT interval,  reduced QT interval,  short QT
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QT interval

Total number of significant genotype-phenotype associations: 11

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Dnajc5b
Dnajc5btm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
2.78×10-08
Dhx15
Dhx15em1(IMPC)Tcp
HET Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
1.58×10-06
Cdc45
Cdc45em1(IMPC)Bay
HET Late adult shortened QT interval QT
Electrocardiogram (ECG)
BCM
IMPC
3.35×10-06
Usp35
Usp35em1(IMPC)J
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
1.59×10-05
Ube4a
Ube4aem1(IMPC)Tcp
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
3.09×10-05
Cdh13
Cdh13tm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
3.79×10-05
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
3.97×10-05
Pcdh18
Pcdh18tm1.1(KOMP)Vlcg
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
5.83×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
6.89×10-05
Setd3
Setd3tm1.1(NCOM)Mfgc
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
TCP
IMPC
8.50×10-05
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
9.38×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.32% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QT interval (11/3477)

0.17% females (6/3462) 0.06% males (2/3458)

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