Phenotype: shortened QT interval

Definition
decrease in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
Synonyms
decreased QT interval,  reduced QT interval,  short QT
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened QT interval

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Dnajc5b
Dnajc5btm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
2.59×10-09
Gas2l1
Gas2l1tm1.1(KOMP)Vlcg
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
1.41×10-06
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
5.27×10-06
Rnf144b
Rnf144btm1b(EUCOMM)Hmgu
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
7.50×10-06
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM   Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
9.69×10-06
Pcdh18
Pcdh18tm1.1(KOMP)Vlcg
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
1.54×10-05
Erlec1
Erlec1em1(IMPC)Mbp
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
3.48×10-05
Tmem256
Tmem256tm1.1(KOMP)Vlcg
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
5.92×10-05
Rac2
Rac2em1(IMPC)Mbp
HOM Early adult shortened QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
6.62×10-05
Thra
Thratm1b(EUCOMM)Wtsi
HET   Late adult shortened QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
9.11×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.55% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened QT interval (10/1832)

0.33% females (6/1829) 0.11% males (2/1829)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter