Genes Phenotypes

Phenotype: prolonged PR interval

Definition
increase in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex
Synonyms
prolonged PR-interval
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged PR interval

Total number of significant genotype-phenotype associations: 20

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Atrn
Atrntm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 5.91×10-08
Pbx3
Pbx3tm1b(EUCOMM)Wtsi 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 1.24×10-06
Grtp1
Grtp1tm1b(EUCOMM)Hmgu 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR TCP | IMPC 7.54×10-06
Smo
Smotm1b(KOMP)Wtsi 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 1.72×10-05
Kbtbd7
Kbtbd7tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR JAX | IMPC 2.47×10-05
Rgs2
Rgs2em1(IMPC)H 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 2.65×10-05
Nmur1
Nmur1tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 3.87×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 5.14×10-05
Dmp1
Dmp1tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 7.49×10-05
Arih2
Arih2tm1.1(KOMP)Vlcg 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 8.00×10-05
Klhdc2
Klhdc2tm1b(EUCOMM)Hmgu 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 9.69×10-05
Wdyhv1
Wdyhv1tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR JAX | IMPC 9.81×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.30% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged PR interval (12/3983)

0.25% females (10/3974) 0.25% males (10/3974)

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