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Genes Phenotypes

Phenotype: prolonged PR interval

Definition
increase in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex
Synonyms
prolonged PR-interval
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged PR interval

Total number of significant genotype-phenotype associations: 30

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Focad
Focadem1(IMPC)Bay 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 7.22×10-09
Pbx3
Pbx3tm1b(EUCOMM)Wtsi 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 1.17×10-08
Ugt2a1
Ugt2a1em1(IMPC)Bay 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 1.69×10-07
Slc9a1
Slc9a1em1(IMPC)Mbp 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 2.76×10-06
Cacna1f
Cacna1ftm1.1(KOMP)Vlcg 		HEM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 4.52×10-06
Klhdc2
Klhdc2tm1b(EUCOMM)Hmgu 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 8.47×10-06
Padi4
Padi4em1(IMPC)Mbp 		HOM Late adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 1.04×10-05
Prdm5
Prdm5em1(IMPC)Tcp 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR TCP | IMPC 1.07×10-05
Usp22
Usp22tm1b(KOMP)Wtsi 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 1.19×10-05
Gdf15
Gdf15tm1b(KOMP)Wtsi 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 1.60×10-05
Grtp1
Grtp1tm1b(EUCOMM)Hmgu 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR TCP | IMPC 1.73×10-05
Plaur
Plaurem1(IMPC)H 		HOM Late adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 2.04×10-05
Mindy4
Mindy4em1(IMPC)H 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 2.71×10-05
Rgs2
Rgs2em1(IMPC)H 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 2.82×10-05
Zfp69
Zfp69tm1b(EUCOMM)Hmgu 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR HMGU | IMPC 3.30×10-05
Nnat
Nnatem1(IMPC)Mbp 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 3.36×10-05
Tmco5
Tmco5tm1b(KOMP)Wtsi 		HOM Late adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 4.42×10-05
Rhobtb1
Rhobtb1em2(IMPC)Ccpcz 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR CCP-IMG | IMPC 4.88×10-05
Prex2
Prex2em1(IMPC)Bay 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 5.17×10-05
Cib3
Cib3em1(IMPC)H 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 6.42×10-05
Gkap1
Gkap1tm2b(EUCOMM)Hmgu 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 6.70×10-05
Hcn1
Hcn1em1(IMPC)H 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 7.05×10-05
Snca
Sncaem1(IMPC)H 		HOM Late adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 7.23×10-05
Dmp1
Dmp1tm1.1(KOMP)Vlcg 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 7.38×10-05
Osbpl5
Osbpl5em1(IMPC)J 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR JAX | IMPC 7.66×10-05
C1qtnf2
C1qtnf2tm2b(KOMP)Wtsi 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 8.60×10-05
Smo
Smotm1b(KOMP)Wtsi 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR BCM | IMPC 8.78×10-05
Faf1
Faf1em1(IMPC)H 		HOM Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 8.79×10-05
Trdmt1
Trdmt1tm1b(EUCOMM)Hmgu 		HET Early adult prolonged PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 8.83×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged PR interval (29/4397)

0.32% females (14/4351) 0.14% males (6/4340)

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