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Genes Phenotypes

Phenotype: increased cardiac output

Definition
greater than normal blood volume pumped by each ventricle per minute
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac output

Total number of significant genotype-phenotype associations: 5

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Shox2
Shox2em1(IMPC)Bay 		HET Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 5.27×10-06
Ces1a
Ces1atm1b(KOMP)Wtsi 		HOM Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 1.81×10-05
AW549877
AW549877tm1b(EUCOMM)Wtsi 		HOM Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 2.37×10-05
Retreg2
Retreg2em2(IMPC)Ccpcz 		HOM Early adult increased cardiac output Echo | Cardiac Output CCP-IMG | IMPC 2.55×10-05
Lep
Leptm1b(EUCOMM)Hmgu 		HOM   Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 4.56×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.39% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac output (5/1284)

0.08% females (1/1277) 0.30% males (3/1000)



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