Phenotype: increased cardiac output

Definition
greater than normal blood volume pumped by each ventricle per minute
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac output

Total number of significant genotype-phenotype associations: 4

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Shox2
Shox2em1(IMPC)Bay
HET Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 5.03×10-06
Ces1a
Ces1atm1b(KOMP)Wtsi
HOM Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 1.92×10-05
AW549877
AW549877tm1b(EUCOMM)Wtsi
HOM Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 2.23×10-05
Lep
Leptm1b(EUCOMM)Hmgu
HOM   Early adult increased cardiac output Echo | Cardiac Output BCM | IMPC 4.60×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.30% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac output (4/1346)

0.07% females (1/1339) 0.19% males (2/1062)



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