Phenotype: decreased cardiac output

Definition
reduction in the blood volume pumped by each ventricle per minute
Synonyms
reduced cardiac output
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac output

Total number of significant genotype-phenotype associations: 9

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased cardiac output Echo | Cardiac Output BCM | IMPC 4.18×10-07
Golt1b
Golt1btm1b(EUCOMM)Wtsi
HOM Early adult decreased cardiac output Echo | Cardiac Output HMGU | IMPC 6.26×10-07
Dhx16
Dhx16tm1b(EUCOMM)Wtsi
HET Early adult decreased cardiac output Echo | Cardiac Output BCM | IMPC 3.68×10-06
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult decreased cardiac output Echo | Cardiac Output BCM | IMPC 8.96×10-06
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM Early adult decreased cardiac output Echo | Cardiac Output BCM | IMPC 9.44×10-06

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.43% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac output (5/1161)

0.35% females (4/1157) 0.57% males (5/884)

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