Genes Phenotypes

Phenotype: decreased cardiac output

Definition
reduction in the blood volume pumped by each ventricle per minute
Synonyms
reduced cardiac output
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac output

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ap4e1
Ap4e1tm1b(KOMP)Wtsi 		HOM postnatal decreased cardiac output Echo | Cardiac Output BCM | IMPC 4.16×10-07
Golt1b
Golt1btm1b(EUCOMM)Wtsi 		HOM postnatal decreased cardiac output Echo | Cardiac Output HMGU | IMPC 6.02×10-07
Nr1d1
Nr1d1tm1(KOMP)Vlcg 		HOM postnatal decreased cardiac output Echo | Cardiac Output BCM | IMPC 9.27×10-06
Slc25a1
Slc25a1tm1b(EUCOMM)Wtsi 		HET postnatal decreased cardiac output Echo | Cardiac Output BCM | IMPC 4.26×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.41% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac output (4/973)

0.41% females (4/967) 0.58% males (4/688)



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