Phenotype: decreased cardiac output

Definition
reduction in the blood volume pumped by each ventricle per minute
Synonyms
reduced cardiac output
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac output

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Xrcc5
Xrcc5em1(IMPC)Ccpcz
HOM Early adult decreased cardiac output Cardiac Output
Echo
CCP-IMG
IMPC
1.38×10-13
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM Early adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
5.22×10-10
Golt1b
Golt1btm1b(EUCOMM)Wtsi
HOM Early adult decreased cardiac output Cardiac Output
Echo
HMGU
IMPC
7.26×10-06
Mdc1
Mdc1em1(IMPC)Bay
HOM Late adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
1.07×10-05
Col11a2
Col11a2tm1b(KOMP)Wtsi
HET Early adult decreased cardiac output Cardiac Output
Echo
HMGU
IMPC
2.78×10-05
Thyn1
Thyn1em1(IMPC)Bay
HOM Late adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
4.49×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
6.31×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.37% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac output (7/1898)

0.16% females (3/1882) 0.31% males (5/1600)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter