Phenotype: decreased cardiac output

Definition
reduction in the blood volume pumped by each ventricle per minute
Synonyms
reduced cardiac output
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac output

Total number of significant genotype-phenotype associations: 5

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM   Early adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
5.22×10-10
Golt1b
Golt1btm1b(EUCOMM)Wtsi
HOM Early adult decreased cardiac output Cardiac Output
Echo
HMGU
IMPC
6.74×10-06
Pcdh20
Pcdh20em1(IMPC)H
HOM   Late adult decreased cardiac output Cardiac Output
Echo
MRC Harwell
IMPC
2.48×10-05
Col11a2
Col11a2tm1b(KOMP)Wtsi
HET Early adult decreased cardiac output Cardiac Output
Echo
HMGU
IMPC
2.78×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult decreased cardiac output Cardiac Output
Echo
BCM
IMPC
3.38×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac output (5/1421)

0.14% females (2/1410) 0.09% males (1/1130)

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