Phenotype: prolonged QT interval

Definition
increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged QT interval

Total number of significant genotype-phenotype associations: 19

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Iah1
Iah1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 9.13×10-11
Laptm4a
Laptm4atm1b(EUCOMM)Hmgu
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 5.03×10-08
Nfat5
Nfat5tm1b(KOMP)Wtsi
HET Early adult prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 3.46×10-07
Rwdd3
Rwdd3tm1b(KOMP)Wtsi
HET Early adult prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 2.85×10-06
Cav1
Cav1em2(IMPC)Ics
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 1.63×10-05
Amigo1
Amigo1tm1.1(KOMP)Vlcg
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 1.80×10-05
Foxk2
Foxk2em1(IMPC)J
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 2.27×10-05
Boc
Boctm1b(KOMP)Wtsi
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc MRC Harwell | IMPC 3.10×10-05
Mon1a
Mon1aem1(IMPC)J
HOM Early adult prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 3.48×10-05
Mfn2
Mfn2tm1b(EUCOMM)Wtsi
HET Early adult prolonged QT interval Electrocardiogram (ECG) | QTc HMGU | IMPC 4.54×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.28% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged QT interval (10/3617)

0.00% females (0/3539) 0.28% males (10/3527)

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