Phenotype: prolonged QT interval

Definition
increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
Synonyms
increased QT interval,  widened QT interval
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged QT interval

Total number of significant genotype-phenotype associations: 15

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Iah1
Iah1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
1.46×10-08
Laptm4a
Laptm4atm1b(EUCOMM)Hmgu
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
3.02×10-08
Dnase1
Dnase1tm1.1(KOMP)Vlcg
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
6.37×10-07
Ergic1
Ergic1em1(IMPC)J
HET Early adult prolonged QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
8.90×10-07
Sowaha
Sowahaem1(IMPC)Mbp
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
1.57×10-06
Gm28729
Gm28729em1(IMPC)J
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
1.94×10-06
Ndrg1
Ndrg1tm2b(KOMP)Wtsi
HOM   Early adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
4.60×10-06
Sh3tc1
Sh3tc1tm1b(EUCOMM)Hmgu
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
8.13×10-06
Ptk6
Ptk6tm1b(EUCOMM)Wtsi
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
1.33×10-05
Mybl2
Mybl2tm1.1(KOMP)Vlcg
HET Early adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
2.27×10-05
Klf16
Klf16em1(IMPC)J
HET   Early adult prolonged QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
4.43×10-05
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HET Early adult prolonged QT interval QT
Electrocardiogram (ECG)
ICS
IMPC
5.20×10-05
Cd36
Cd36em1(IMPC)Mbp
HOM   Late adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
7.58×10-05
Pdk2
Pdk2em1(IMPC)Mbp
HOM   Late adult prolonged QT interval QT
Electrocardiogram (ECG)
UC Davis
IMPC
8.75×10-05
Eva1a
Eva1aem1(IMPC)J
HOM Early adult prolonged QT interval QT
Electrocardiogram (ECG)
JAX
IMPC
9.58×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.82% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged QT interval (15/1832)

0.11% females (2/1829) 0.49% males (9/1829)

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