Phenotype: prolonged QT interval

Definition
increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time, and is measured from the beginning of the QRS complex to the end of the T wave
Synonyms
widened QT interval,  long QT syndrome,  increased QT interval
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged QT interval

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Laptm4a
Laptm4atm1b(EUCOMM)Hmgu
HOM postnatal prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 1.21×10-12
Iah1
Iah1tm1b(EUCOMM)Hmgu
HOM postnatal prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 3.88×10-06
Nfat5
Nfat5tm1b(KOMP)Wtsi
HET postnatal prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 5.54×10-06
Scarb1
Scarb1tm1b(EUCOMM)Wtsi
HET postnatal prolonged QT interval Electrocardiogram (ECG) | QTc BCM | IMPC 8.68×10-06
Rwdd3
Rwdd3tm1b(KOMP)Wtsi
HET postnatal prolonged QT interval Electrocardiogram (ECG) | QTc ICS | IMPC 9.57×10-06
Amigo1
Amigo1tm1.1(KOMP)Vlcg
HOM postnatal prolonged QT interval Electrocardiogram (ECG) | QTc JAX | IMPC 2.77×10-05
Yju2
Yju2tm1b(KOMP)Wtsi
HET postnatal prolonged QT interval Electrocardiogram (ECG) | QTc BCM | IMPC 4.06×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.26% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged QT interval (7/2677)

0.19% females (5/2627) 0.19% males (5/2637)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter