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Genes Phenotypes

Phenotype: thick ventricular wall

Definition
increased depth of the cardiac wall of the heart ventricles
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 22

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall Echo | LVPWd MRC Harwell | IMPC 3.11×10-15
Gngt2
Gngt2em1(IMPC)Bay 		HOM Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 1.34×10-09
Abcg8
Abcg8tm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWd CCP-IMG | IMPC 1.51×10-07
Nudt5
Nudt5tm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 2.41×10-07
Lsm1
Lsm1tm1b(EUCOMM)Hmgu 		HET Early adult thick ventricular wall Echo | LVPWd HMGU | IMPC 2.16×10-06
Erg
Ergem1(IMPC)Bay 		HET Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 3.92×10-06
Fzd8
Fzd8em1(IMPC)Bay 		HOM Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 4.07×10-06
Bsdc1
Bsdc1em1(IMPC)Bay 		HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 4.14×10-06
Grem2
Grem2em1(IMPC)Bay 		HET Early adult thick ventricular wall Echo | LVPWd BCM | IMPC 4.43×10-06
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi 		HET Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 7.28×10-06
Zfp235
Zfp235tm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 8.33×10-06
Fcrl6
Fcrl6tm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 9.31×10-06
Nos1ap
Nos1aptm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 1.13×10-05
Ptch2
Ptch2tm3b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall Echo | LVPWs MRC Harwell | IMPC 2.10×10-05
Atad5
Atad5em1(IMPC)Bay 		HET Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 2.43×10-05
Mpzl2
Mpzl2tm1b(EUCOMM)Hmgu 		HET Early adult thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 2.73×10-05
Tmem138
Tmem138tm1b(EUCOMM)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWd BCM | IMPC 4.18×10-05
Apol10b
Apol10btm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWd BCM | IMPC 6.05×10-05
Myof
Myoftm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 6.37×10-05
Fbxo36
Fbxo36tm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall Echo | LVPWd MARC | IMPC 7.21×10-05
Cntn3
Cntn3em1(IMPC)Marc 		HOM Early adult thick ventricular wall Echo | LVAWs MARC | IMPC 8.36×10-05
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 9.52×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (22/1653)

0.49% females (8/1632) 0.51% males (7/1360)

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