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Phenotype: thick ventricular wall

Definition
increased depth of the cardiac wall of the heart ventricles
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 23

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu 		HOM   Early adult thick ventricular wall LVPWd
Echo		 MRC Harwell
IMPC		 3.66×10-15
Gngt2
Gngt2em1(IMPC)Bay 		HOM Early adult thick ventricular wall LVAWs
Echo		 BCM
IMPC		 1.40×10-09
Nudt5
Nudt5tm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall LVAWs
Echo		 BCM
IMPC		 2.71×10-07
Abcg8
Abcg8tm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall LVPWd
Echo		 CCP-IMG
IMPC		 3.29×10-07
Lsm1
Lsm1tm1b(EUCOMM)Hmgu 		HET Early adult thick ventricular wall LVPWd
Echo		 HMGU
IMPC		 2.62×10-06
Erg
Ergem1(IMPC)Bay 		HET Early adult thick ventricular wall LVPWs
Echo		 BCM
IMPC		 3.54×10-06
Fzd8
Fzd8em1(IMPC)Bay 		HOM Early adult thick ventricular wall LVAWs
Echo		 BCM
IMPC		 3.74×10-06
Grem2
Grem2em1(IMPC)Bay 		HET Early adult thick ventricular wall LVPWd
Echo		 BCM
IMPC		 3.92×10-06
Bsdc1
Bsdc1em1(IMPC)Bay 		HOM Early adult thick ventricular wall LVPWs
Echo		 BCM
IMPC		 4.06×10-06
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi 		HET   Early adult thick ventricular wall LVAWs
Echo		 BCM
IMPC		 6.89×10-06
Mpzl2
Mpzl2tm1b(EUCOMM)Hmgu 		HET Early adult thick ventricular wall LVAWs
Echo		 MRC Harwell
IMPC		 7.09×10-06
Zfp235
Zfp235tm1b(KOMP)Wtsi 		HOM   Early adult thick ventricular wall LVPWs
Echo		 BCM
IMPC		 8.19×10-06
Nos1ap
Nos1aptm1b(KOMP)Wtsi 		HOM   Early adult thick ventricular wall LVPWs
Echo		 BCM
IMPC		 1.13×10-05
Ptch2
Ptch2tm3b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall LVPWs
Echo		 MRC Harwell
IMPC		 1.35×10-05
Myof
Myoftm1b(EUCOMM)Hmgu 		HOM Early adult thick ventricular wall LVPWs
Echo		 BCM
IMPC		 2.14×10-05
Atad5
Atad5em1(IMPC)Bay 		HET Early adult thick ventricular wall LVAWs
Echo		 BCM
IMPC		 2.35×10-05
Fcrl6
Fcrl6tm1b(KOMP)Wtsi 		HOM   Early adult thick ventricular wall LVAWs
Echo		 MRC Harwell
IMPC		 2.69×10-05
Calb1
Calb1em1(IMPC)Ccpcz 		HOM   Early adult thick ventricular wall LVAWs
Echo		 CCP-IMG
IMPC		 3.06×10-05
Tmem138
Tmem138tm1b(EUCOMM)Wtsi 		HOM Early adult thick ventricular wall LVPWd
Echo		 BCM
IMPC		 4.14×10-05
Apol10b
Apol10btm1b(KOMP)Wtsi 		HOM Early adult thick ventricular wall LVPWd
Echo		 BCM
IMPC		 6.36×10-05
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu 		HOM   Early adult thick ventricular wall LVAWs
Echo		 MRC Harwell
IMPC		 7.85×10-05
Cntn3
Cntn3em1(IMPC)Marc 		HOM   Early adult thick ventricular wall LVAWs
Echo		 MARC
IMPC		 8.36×10-05
Fbxo36
Fbxo36tm1b(KOMP)Wtsi 		HOM   Early adult thick ventricular wall LVPWd
Echo		 MARC
IMPC		 9.98×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.24% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (23/1848)

0.38% females (7/1824) 0.45% males (7/1543)

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