Phenotype: thick ventricular wall

Definition
increased depth of the cardiac wall of the heart ventricles
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 24

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM postnatal thick ventricular wall Echo | LVPWd MRC Harwell | IMPC 1.59×10-15
Fzd8
Fzd8em1(IMPC)Bay
HOM postnatal thick ventricular wall Echo | LVAWs BCM | IMPC 9.88×10-09
Apol10b
Apol10btm1b(KOMP)Wtsi
HOM postnatal thick ventricular wall Echo | LVPWd BCM | IMPC 2.81×10-08
Prdm4
Prdm4tm1b(EUCOMM)Hmgu
HOM postnatal thick ventricular wall Echo | LVPWs MRC Harwell | IMPC 1.51×10-06
Mthfd2
Mthfd2tm1b(EUCOMM)Wtsi
HET postnatal thick ventricular wall Echo | LVAWs BCM | IMPC 2.33×10-06
Yipf5
Yipf5tm1b(EUCOMM)Hmgu
HET postnatal thick ventricular wall Echo | LVPWd ICS | IMPC 5.74×10-06
Erg
Ergem1(IMPC)Bay
HET postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 6.56×10-06
Zfp235
Zfp235tm1b(KOMP)Wtsi
HOM postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 7.95×10-06
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
HOM postnatal thick ventricular wall Echo | LVPWd MARC | IMPC 1.15×10-05
Rcn3
Rcn3tm1b(EUCOMM)Hmgu
HET postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 1.26×10-05
Hmcn2
Hmcn2tm1b(EUCOMM)Wtsi
HOM postnatal thick ventricular wall Echo | LVPWs BCM | IMPC 1.58×10-05
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET postnatal thick ventricular wall Echo | LVPWd HMGU | IMPC 1.69×10-05
Mpzl2
Mpzl2tm1b(EUCOMM)Hmgu
HET postnatal thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 2.08×10-05
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM postnatal thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 7.20×10-05
Vps13c
Vps13ctm1b(EUCOMM)Hmgu
HOM postnatal thick ventricular wall Echo | LVPWs HMGU | IMPC 7.76×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.14% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (15/1313)

1.00% females (13/1298) 1.07% males (11/1024)

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