Phenotype: thick ventricular wall

Definition
increased depth of the cardiac wall of the heart ventricles
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 39

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM   Early adult thick ventricular wall LVPWd
Echo
MRC Harwell
IMPC
3.77×10-15
Lemd3
Lemd3em1(IMPC)Bay
HET Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
5.25×10-09
Erg
Ergem1(IMPC)Bay
HET Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
8.85×10-09
Igfbp3
Igfbp3tm1b(KOMP)Wtsi
HOM   Early adult thick ventricular wall LVPWd
Echo
MRC Harwell
IMPC
6.05×10-08
Memo1
Memo1tm1b(EUCOMM)Wtsi
HET Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
1.33×10-07
Cntn3
Cntn3em1(IMPC)Marc
HOM   Early adult thick ventricular wall LVPWs
Echo
MARC
IMPC
4.69×10-07
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
HOM Early adult thick ventricular wall LVPWd
Echo
MARC
IMPC
4.85×10-07
Atp1a1
Atp1a1em1(IMPC)Ccpcz
HET Early adult thick ventricular wall LVAWs
Echo
CCP-IMG
IMPC
7.45×10-07
Iqcb1
Iqcb1em1(IMPC)Bay
HET Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
9.19×10-07
Oxa1l
Oxa1lem1(IMPC)Bay
HET   Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
2.52×10-06
Mdh1
Mdh1em1(IMPC)Bay
HET Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
2.57×10-06
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM   Early adult thick ventricular wall LVAWs
Echo
MRC Harwell
IMPC
2.61×10-06
Cbl
Cbltm1b(EUCOMM)Hmgu
HET   Early adult thick ventricular wall LVPWd
Echo
ICS
IMPC
3.29×10-06
Fzd8
Fzd8em1(IMPC)Bay
HOM Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
3.36×10-06
Tmem138
Tmem138tm1b(EUCOMM)Wtsi
HOM Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
4.04×10-06
Prdm15
Prdm15tm1b(EUCOMM)Wtsi
HET   Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
4.35×10-06
Arfgef1
Arfgef1em1(IMPC)Hmgu
HET Early adult thick ventricular wall LVPWd
Echo
HMGU
IMPC
6.69×10-06
Gm614
Gm614em1(IMPC)Bay
HET   Early adult thick ventricular wall LVPWs
Echo
BCM
IMPC
8.00×10-06
Prdm4
Prdm4tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall LVPWs
Echo
MRC Harwell
IMPC
9.39×10-06
Map3k12
Map3k12tm1b(EUCOMM)Hmgu
HET Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
9.82×10-06
Rxfp3
Rxfp3em1(IMPC)Bay
HOM   Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
1.04×10-05
Rnf41
Rnf41em1(IMPC)Bay
HOM   Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
1.22×10-05
Ap3m2
Ap3m2em2(IMPC)H
HOM   Early adult thick ventricular wall LVPWd
Echo
MRC Harwell
IMPC
1.83×10-05
Dhx16
Dhx16tm1b(EUCOMM)Wtsi
HET Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
2.09×10-05
Zfp235
Zfp235tm1b(KOMP)Wtsi
HOM   Early adult thick ventricular wall LVPWs
Echo
BCM
IMPC
2.80×10-05
Ucp1
Ucp1tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall LVPWd
Echo
HMGU
IMPC
3.36×10-05
Ascc1
Ascc1em1(IMPC)Bay
HET Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
3.44×10-05
Tonsl
Tonslem1(IMPC)Bay
HET   Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
3.86×10-05
Yipf5
Yipf5tm1b(EUCOMM)Hmgu
HET Early adult thick ventricular wall LVPWd
Echo
ICS
IMPC
3.90×10-05
Ndufa6
Ndufa6em1(IMPC)Bay
HET Early adult thick ventricular wall LVPWs
Echo
BCM
IMPC
4.04×10-05
Myof
Myoftm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall LVPWs
Echo
BCM
IMPC
4.20×10-05
Creld2
Creld2tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall LVPWd
Echo
MRC Harwell
IMPC
5.61×10-05
Slc2a12
Slc2a12em2(IMPC)Bay
HOM   Early adult thick ventricular wall LVAWs
Echo
BCM
IMPC
5.62×10-05
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult thick ventricular wall LVPWd
Echo
CCP-IMG
IMPC
5.63×10-05
Fcrl6
Fcrl6tm1b(KOMP)Wtsi
HOM   Early adult thick ventricular wall LVAWs
Echo
MRC Harwell
IMPC
7.16×10-05
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET   Early adult thick ventricular wall LVPWd
Echo
HMGU
IMPC
7.95×10-05
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET   Late adult thick ventricular wall LVPWd
Echo
ICS
IMPC
8.03×10-05
Arhgef17
Arhgef17em1(IMPC)Bay
HOM Early adult thick ventricular wall LVPWd
Echo
BCM
IMPC
8.94×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.78% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (38/2131)

0.62% females (13/2097) 0.50% males (9/1818)

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