Phenotype: thick ventricular wall

Definition
increased depth of the cardiac wall of the heart ventricles
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thick ventricular wall

Total number of significant genotype-phenotype associations: 25

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall Echo | LVPWd MRC Harwell | IMPC 3.50×10-15
Zfp235
Zfp235tm1b(KOMP)Wtsi
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 8.49×10-08
Fzd8
Fzd8em1(IMPC)Bay
HOM Early adult thick ventricular wall Echo | LVAWs BCM | IMPC 1.52×10-07
Erg
Ergem1(IMPC)Bay
HET Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 3.12×10-06
Yipf5
Yipf5tm1b(EUCOMM)Hmgu
HET Early adult thick ventricular wall Echo | LVPWd ICS | IMPC 5.74×10-06
Slurp1
Slurp1tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 7.11×10-06
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 9.48×10-06
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
HOM Early adult thick ventricular wall Echo | LVPWd MARC | IMPC 1.15×10-05
Rxfp3
Rxfp3em1(IMPC)Bay
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 1.67×10-05
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Early adult thick ventricular wall Echo | LVPWd HMGU | IMPC 1.69×10-05
Myof
Myoftm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 3.69×10-05
Hmcn2
Hmcn2tm1b(EUCOMM)Wtsi
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 4.94×10-05
Vps13c
Vps13ctm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall Echo | LVPWs HMGU | IMPC 7.46×10-05
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu
HOM Early adult thick ventricular wall Echo | LVAWs MRC Harwell | IMPC 7.68×10-05
Apol10b
Apol10btm1b(KOMP)Wtsi
HOM Early adult thick ventricular wall Echo | LVPWs BCM | IMPC 7.77×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.99% of tested genes with null mutations on a B6N genetic background have a phenotype association to thick ventricular wall (15/1518)

0.86% females (13/1504) 0.97% males (12/1237)

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