Definition
greater than average weight of the heart compared to controls
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased heart weight
Total number of significant genotype-phenotype associations: 109
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Procedure | Parameter | Phenotyping Center | Source | P Value | |
|---|---|---|---|---|---|---|---|---|
| Alpk3 Alpk3tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 0.00 | ||
| Mybpc3 Mybpc3tm1a(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | EuroPhenome | 1.17×10-19 | ||
| Slc25a4 Slc25a4tm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 1.89×10-19 | ||
| Gnas Gnastm1Jop |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | EuroPhenome | 2.14×10-11 | ||
| Sik1 Sik1tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | UC Davis | IMPC | 3.64×10-11 | ||
| Ric1 Ric1tm1a(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | MGP | 6.73×10-11 | ||
| Ttc39a Ttc39atm1b(KOMP)Mbp |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 1.91×10-10 | ||
| Ndufs3 Ndufs3tm1a(EUCOMM)Wtsi |
HET | postnatal | increased heart weight | Heart Dissection | Heart weight | WTSI | MGP | 2.25×10-09 | ||
| Rab19 Rab19tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 3.41×10-09 | ||
| Ash1l Ash1ltm2b(EUCOMM)Hmgu |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | MARC | IMPC | 3.99×10-09 | ||
| Tbl1xr1 Tbl1xr1tm1b(EUCOMM)Hmgu |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | HMGU | IMPC | 5.29×10-09 | ||
| Grm6 Grm6tm1b(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 1.90×10-08 | ||
| Lcn2 Lcn2tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 2.64×10-08 | ||
| Rap1gap2 Rap1gap2tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 3.62×10-08 | ||
| Cidec Cidectm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | HMGU | EuroPhenome | 5.10×10-08 | ||
| Srcin1 Srcin1tm1.1(KOMP)Vlcg |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 6.07×10-08 | ||
| Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 7.23×10-08 | ||
| Itch Itchtm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 7.75×10-08 | ||
| Dynlrb2 Dynlrb2tm1a(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 8.06×10-08 | ||
| Exd1 Exd1tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 9.62×10-08 | ||
| Asns Asnstm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | MGP | 1.61×10-07 | ||
| Tead1 Tead1tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 3.22×10-07 | ||
| 2810408A11Rik 2810408A11Riktm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | MGP | 3.77×10-07 | ||
| Mtmr12 Mtmr12tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 6.70×10-07 | ||
| Dcbld2 Dcbld2tm1a(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 6.99×10-07 | ||
| Gpld1 Gpld1tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | UC Davis | IMPC | 7.34×10-07 | ||
| Gimap6 Gimap6tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 8.01×10-07 | ||
| Smurf2 Smurf2tm1b(EUCOMM)Wtsi |
HET | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 8.59×10-07 | ||
| Acsl5 Acsl5tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | UC Davis | IMPC | 9.13×10-07 | ||
| Nos1ap Nos1aptm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 1.04×10-06 | ||
| Mpdz Mpdzem1(IMPC)J |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 2.11×10-06 | ||
| Gpr101 Gpr101tm1b(KOMP)Mbp |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 2.67×10-06 | ||
| Lama4 Lama4tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | UC Davis | IMPC | 2.79×10-06 | ||
| Epb41l5 Epb41l5tm1a(EUCOMM)Hmgu |
HET | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | MGP | 3.14×10-06 | ||
| Rimklb Rimklbtm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 3.35×10-06 | ||
| Rnf10 Rnf10tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | TCP | IMPC | 4.06×10-06 | ||
| Rpa1 Rpa1tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 5.13×10-06 | ||
| Lrrc15 Lrrc15tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 5.22×10-06 | ||
| Bcl7a Bcl7atm1b(EUCOMM)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 5.63×10-06 | ||
| Col1a2 Col1a2tm1b(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 5.87×10-06 | ||
| Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | KMPC | IMPC | 6.64×10-06 | ||
| Bod1 Bod1tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | MARC | IMPC | 7.93×10-06 | ||
| Hcn1 Hcn1em1(IMPC)H |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 8.11×10-06 | ||
| Pabpc4 Pabpc4tm1a(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 8.27×10-06 | ||
| Lep Leptm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 8.62×10-06 | ||
| Rab36 Rab36tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 8.82×10-06 | ||
| Pacsin2 Pacsin2tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 9.89×10-06 | ||
| Ptpn5 Ptpn5tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 1.01×10-05 | ||
| Elmod1 Elmod1tm1b(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 1.28×10-05 | ||
| Stx8 Stx8tm2a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | EuroPhenome | 1.35×10-05 | ||
| Fbxo43 Fbxo43em1(IMPC)Marc |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | MARC | IMPC | 1.81×10-05 | ||
| Tnfaip1 Tnfaip1tm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | EuroPhenome | 2.46×10-05 | ||
| Tmem255b Tmem255btm1a(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | MGP | 2.56×10-05 | ||
| Gabarapl2 Gabarapl2tm1b(EUCOMM)Hmgu |
HET | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 2.77×10-05 | ||
| Gsto2 Gsto2tm2a(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 2.92×10-05 | ||
| Dsg2 Dsg2tm1b(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | BCM | IMPC | 3.09×10-05 | ||
| Sparc Sparctm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | WTSI | MGP | 3.30×10-05 | ||
| Timm50 Timm50tm1b(EUCOMM)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 3.65×10-05 | ||
| Bbox1 Bbox1tm1b(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 4.33×10-05 | ||
| Dppa1 Dppa1tm1a(KOMP)Wtsi |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | WTSI | IMPC | 4.39×10-05 | ||
| Lrig1 Lrig1tm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart Dissection | Heart weight | WTSI | MGP | 4.42×10-05 | ||
| Elk4 Elk4tm1a(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | HMGU | EuroPhenome | 4.49×10-05 | ||
| Pink1 Pink1tm1b(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 4.72×10-05 | ||
| Ttll10 Ttll10em1(IMPC)J |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 5.32×10-05 | ||
| Gimap8 Gimap8tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 5.34×10-05 | ||
| Zc3hc1 Zc3hc1tm1a(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Dissection | Heart weight | WTSI | EuroPhenome | 5.44×10-05 | ||
| Rcc2 Rcc2tm1b(EUCOMM)Wtsi |
HOM | postnatal | increased heart weight | Organ Weight | Heart weight | MRC Harwell | IMPC | 5.63×10-05 | ||
| Xylb Xylbtm1a(EUCOMM)Hmgu |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | MRC Harwell | EuroPhenome | 6.26×10-05 | ||
| Ino80 Ino80tm1a(EUCOMM)Hmgu |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 6.40×10-05 | ||
| Hspb1 Hspb1tm1.1(KOMP)Vlcg |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 7.65×10-05 | ||
| Ccdc57 Ccdc57tm1a(EUCOMM)Wtsi |
HET | postnatal | increased heart weight | Heart Dissection | Heart weight | WTSI | EuroPhenome | 7.82×10-05 | ||
| Dcp2 Dcp2tm1b(KOMP)Wtsi |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | ICS | IMPC | 8.29×10-05 | ||
| Nalcn Nalcnem1(IMPC)Mbp |
HET | postnatal | increased heart weight | Heart Weight | Heart weight | UC Davis | IMPC | 8.35×10-05 | ||
| Phex Phexnot yet available |
HOM | postnatal | increased heart weight | Heart weight/tibia length | Heart weight | HMGU | EuroPhenome | 9.56×10-05 | ||
| Clstn2 Clstn2em1(IMPC)J |
HOM | postnatal | increased heart weight | Heart Weight | Heart weight | JAX | IMPC | 9.82×10-05 |