Genes Phenotypes

Phenotype: dilated heart left ventricle

Definition
the luminal space of the lower left chamber of the heart is increased in volume or area, usually with an increase in contained fluid
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with dilated heart left ventricle

Total number of significant genotype-phenotype associations: 11

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Col1a2
Col1a2tm1b(EUCOMM)Wtsi 		HOM Early adult dilated heart left ventricle Echo | LVIDd BCM | IMPC 1.05×10-06
Mapkap1
Mapkap1tm1b(EUCOMM)Wtsi 		HET Early adult dilated heart left ventricle Echo | LVIDs BCM | IMPC 1.09×10-06
Arhgap40
Arhgap40tm1b(KOMP)Wtsi 		HOM Early adult dilated heart left ventricle Echo | End-Diastolic Diameter BCM | IMPC 2.33×10-06
Grem2
Grem2em1(IMPC)Bay 		HET Early adult dilated heart left ventricle Echo | End-Diastolic Diameter BCM | IMPC 4.45×10-06
Ap1ar
Ap1artm2b(EUCOMM)Hmgu 		HOM Early adult dilated heart left ventricle Echo | LVIDd BCM | IMPC 7.83×10-06
Snx25
Snx25tm1b(KOMP)Wtsi 		HET Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 1.98×10-05
Abhd3
Abhd3em1(IMPC)Marc 		HOM Early adult dilated heart left ventricle Echo | LVIDs MARC | IMPC 2.27×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.44% of tested genes with null mutations on a B6N genetic background have a phenotype association to dilated heart left ventricle (7/1597)

0.00% females (0/1548) 0.54% males (7/1286)

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