Phenotype: dilated heart left ventricle

Definition
the luminal space of the lower left chamber of the heart is increased in volume or area, usually with an increase in contained fluid
Synonyms
dilated cardiac left ventricle,  cardiac left ventricle dilation,  heart left ventricular dilation,  heart left ventricle dilation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with dilated heart left ventricle

Total number of significant genotype-phenotype associations: 30

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM   Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
MRC Harwell
IMPC
0.00
Zfp280d
Zfp280dem1(IMPC)Hmgu
HOM Early adult dilated heart left ventricle LVIDs
Echo
HMGU
IMPC
7.65×10-21
Ints6l
Ints6lem1(IMPC)Marc
HEM   Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
7.56×10-09
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM Early adult dilated heart left ventricle LVIDd
Echo
BCM
IMPC
9.24×10-08
Zdhhc2
Zdhhc2tm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle LVIDd
Echo
MARC
IMPC
1.64×10-07
Pex1
Pex1tm1e.1(EUCOMM)Hmgu
HET Early adult dilated heart left ventricle LVIDs
Echo
HMGU
IMPC
2.20×10-07
Hells
Hellstm1b(EUCOMM)Wtsi
HET Early adult dilated heart left ventricle LVIDd
Echo
HMGU
IMPC
8.78×10-07
Grem2
Grem2em1(IMPC)Bay
HET   Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
BCM
IMPC
3.26×10-06
Acot12
Acot12em1(IMPC)Hmgu
HOM Early adult dilated heart left ventricle LVIDs
Echo
HMGU
IMPC
3.88×10-06
Dsg2
Dsg2tm1b(EUCOMM)Wtsi
HOM   Early adult dilated heart left ventricle End-Systolic Diameter
Echo
BCM
IMPC
4.31×10-06
Fam126a
Fam126aem1(IMPC)Ccpcz
HOM   Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
CCP-IMG
IMPC
6.10×10-06
Gsdmd
Gsdmdem1(IMPC)Marc
HOM   Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
9.90×10-06
Ppp1r14d
Ppp1r14dtm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
1.47×10-05
Atg4d
Atg4dem1(IMPC)Marc
HOM   Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
1.51×10-05
Dusp7
Dusp7tm1(KOMP)Wtsi
HOM Early adult dilated heart left ventricle LVIDd
Echo
MARC
IMPC
1.95×10-05
Snx25
Snx25tm1b(KOMP)Wtsi
HET Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
2.01×10-05
Wars
Warstm1b(EUCOMM)Hmgu
HET   Early adult dilated heart left ventricle LVIDs
Echo
HMGU
IMPC
2.39×10-05
Ufm1
Ufm1em1(IMPC)Marc
HET Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
2.56×10-05
Mapkap1
Mapkap1tm1b(EUCOMM)Wtsi
HET Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
BCM
IMPC
4.60×10-05
Eddm3b
Eddm3btm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle LVIDd
Echo
MARC
IMPC
6.15×10-05
Abhd3
Abhd3em1(IMPC)Marc
HOM Early adult dilated heart left ventricle LVIDs
Echo
MARC
IMPC
6.18×10-05
Pcdhgc3
Pcdhgc3em1(IMPC)Hmgu
HOM Early adult dilated heart left ventricle LVIDs
Echo
HMGU
IMPC
6.43×10-05
Cluh
Cluhem1(IMPC)Ccpcz
HET Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
CCP-IMG
IMPC
6.57×10-05
Ncam2
Ncam2tm1b(EUCOMM)Hmgu
HOM Early adult dilated heart left ventricle LVIDs
Echo
ICS
IMPC
8.28×10-05
Ap1ar
Ap1artm2b(EUCOMM)Hmgu
HOM Early adult dilated heart left ventricle End-Diastolic Diameter
Echo
BCM
IMPC
9.20×10-05
Efcab14
Efcab14tm1b(KOMP)Wtsi
HOM Early adult dilated heart left ventricle LVIDs
Echo
BCM
IMPC
9.22×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.23% of tested genes with null mutations on a B6N genetic background have a phenotype association to dilated heart left ventricle (26/2109)

0.34% females (7/2075) 0.83% males (15/1801)

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