Phenotype: small heart

Definition
reduced size of the heart relative to average
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with small heart

Total number of significant genotype-phenotype associations: 169

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Adamts1
Adamts1em1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Bbs1
Bbs1em1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Cacna1i
Cacna1itm1b(KOMP)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart BCM | IMPC 0.00
Cand1
Cand1em1(IMPC)Mbp
HET Late adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Csnk2a2
Csnk2a2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Dennd1a
Dennd1aem1(IMPC)Mbp
HET Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Fam83h
Fam83hem1(IMPC)Ccpcz
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart CCP-IMG | IMPC 0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 0.00
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 0.00
H1f0
H1f0em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Hectd3
Hectd3tm1(NCOM)Cmhd
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Irf3
Irf3em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Kdm1a
Kdm1atm1(NCOM)Mfgc
HET Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Lhcgr
Lhcgrtm1(KOMP)Vlcg
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MARC | IMPC 0.00
Npas2
Npas2em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Pramel12
Pramel12em1(IMPC)Mbp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Slc6a2
Slc6a2tm1b(EUCOMM)Hmgu
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart MRC Harwell | IMPC 0.00
Ssbp2
Ssbp2tm1b(KOMP)Wtsi
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Trh
Trhem1(IMPC)Tcp
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart TCP | IMPC 0.00
Wdr11
Wdr11em1(IMPC)Mbp
HET Late adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Wnt5b
Wnt5btm1.1(KOMP)Vlcg
HOM Early adult small heart Gross Pathology and Tissue Collection | Heart UC Davis | IMPC 0.00
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 1.01×10-22
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.73×10-21
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.09×10-18
Plcb4
Plcb4tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.28×10-15
Tmem248
Tmem248tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.33×10-14
Duox2
Duox2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.11×10-13
Map7d1
Map7d1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.67×10-13
Dmp1
Dmp1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 9.89×10-13
Ptp4a3
Ptp4a3em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.56×10-10
Kctd1
Kctd1em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.44×10-10
Tlr4
Tlr4tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 4.49×10-10
Camk1d
Camk1dem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.16×10-09
Mul1
Mul1em1(IMPC)H
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.24×10-09
Kiss1r
Kiss1rtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.11×10-09
Tox3
Tox3tm1b(KOMP)Mbp
HET Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 8.06×10-09
Rab28
Rab28em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 9.36×10-09
Gopc
Gopctm1e.1(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.21×10-08
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.82×10-08
Eid2
Eid2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 3.00×10-08
Nucb1
Nucb1em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 4.18×10-08
Snx10
Snx10em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 8.53×10-08
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight HMGU | IMPC 1.09×10-07
Asic1
Asic1em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.49×10-07
Zfp202
Zfp202em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.52×10-07
Elmod3
Elmod3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.57×10-07
Slc25a25
Slc25a25tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.78×10-07
Nr1h3
Nr1h3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.08×10-07
Hrh4
Hrh4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 3.34×10-07
Trh
Trhem1(IMPC)Tcp
HOM Early adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 6.13×10-07
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 7.81×10-07
Opn3
Opn3em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.56×10-07
Srek1
Srek1em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.02×10-06
Lrrtm1
Lrrtm1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.26×10-06
Grin2d
Grin2dtm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 1.63×10-06
Ifitm1
Ifitm1not yet assigned
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 1.75×10-06
Siglec1
Siglec1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.82×10-06
Kcnt2
Kcnt2em1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.96×10-06
Rnf24
Rnf24em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.01×10-06
P2rx4
P2rx4tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.56×10-06
Klhl29
Klhl29tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 2.84×10-06
Clcnkb
Clcnkbem1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.10×10-06
Krt26
Krt26em1(IMPC)KMPC
HOM Late adult decreased heart weight Heart Weight | Heart weight KMPC | IMPC 3.28×10-06
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 3.42×10-06
Cyp17a1
Cyp17a1tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 3.59×10-06
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 3.94×10-06
Clrn2
Clrn2em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.00×10-06
Shfl
Shfltm1.1(KOMP)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 5.03×10-06
Neurl4
Neurl4em1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.34×10-06
Trim39
Trim39tm1b(EUCOMM)Hmgu
HOM Late adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 9.01×10-06
Prf1
Prf1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.01×10-05
Arhgap11a
Arhgap11aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.24×10-05
Il17rd
Il17rdtm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.54×10-05
Nucb1
Nucb1em1(IMPC)Mbp
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 1.62×10-05
Cmpk2
Cmpk2tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.66×10-05
Mme
Mmeem1(IMPC)Mbp
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 1.75×10-05
Otop3
Otop3tm1a(EUCOMM)Wtsi
HOM Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 1.80×10-05
Kctd15
Kctd15tm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 1.85×10-05
Thsd4
Thsd4em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 1.97×10-05
Slc22a8
Slc22a8tm1b(KOMP)Wtsi
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.23×10-05
Adgrf3
Adgrf3em1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 2.34×10-05
Elmod2
Elmod2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.53×10-05
Gsg1l
Gsg1lem1(IMPC)Mbp
HOM Late adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.87×10-05
Atrn
Atrntm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 2.93×10-05
Dram1
Dram1tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.39×10-05
Coq2
Coq2tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 3.58×10-05
Rhot2
Rhot2tm1(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Dissection | Heart weight WTSI | MGP 3.81×10-05
Kctd13
Kctd13em2(IMPC)Ics
HOM Early adult decreased heart weight Heart Weight | Heart weight ICS | IMPC 4.01×10-05
Ncor2
Ncor2Ncor2
HET Early adult decreased heart weight Heart weight/tibia length | Heart weight ICS | EuroPhenome 4.13×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Heart Weight | Heart weight RBRC | IMPC 4.30×10-05
Otogl
Otoglem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 4.41×10-05
Cybrd1
Cybrd1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 5.07×10-05
Wdr81
Wdr81em1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 5.95×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.19×10-05
Usp24
Usp24tm1a(KOMP)Wtsi
HOM Early adult decreased heart weight Heart Weight | Heart weight WTSI | IMPC 6.24×10-05
Cntnap5a
Cntnap5aem1(IMPC)J
HOM Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 6.41×10-05
F10
F10tm1b(EUCOMM)Hmgu
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 6.43×10-05
Arhgap33
Arhgap33tm1b(KOMP)Wtsi
HET Early adult decreased heart weight Heart Weight | Heart weight BCM | IMPC 6.70×10-05
Fndc9
Fndc9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Organ Weight | Heart weight UC Davis | IMPC 6.86×10-05
Tenm4
Tenm4em1(IMPC)Tcp
HOM Late adult decreased heart weight Heart Weight | Heart weight TCP | IMPC 7.61×10-05
Pawr
Pawrtm1b(EUCOMM)Wtsi
HET Early adult decreased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 7.87×10-05
Trf
Trfem1(IMPC)J
HET Early adult decreased heart weight Heart Weight | Heart weight JAX | IMPC 8.39×10-05
Vsir
Vsirtm1.1(KOMP)Vlcg
HOM Early adult decreased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.84×10-05
Phf11a
Phf11atm1b(NCOM)Mfgc
HET Early adult decreased heart weight Heart Weight | Heart weight MARC | IMPC 9.02×10-05

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 The way we measure

 Phenotype associations stats

140.54% of tested genes with null mutations on a B6N genetic background have a phenotype association to small heart (104/74)

22.54% females (16/71) 152.46% males (93/61)

Select a parameter    



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