Phenotype: hemorrhage

Definition
loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels
Synonyms
bleeding,  haemorrhage
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with hemorrhage

Total number of significant genotype-phenotype associations: 127

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
4932438A13Rik
4932438A13Riktm1b(EUCOMM)Hmgu
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Ache
Acheem1(IMPC)Mbp
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage UC Davis | IMPC 0.00
Arhgap28
Arhgap28em1(IMPC)Mbp
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage UC Davis | IMPC 0.00
Arid3a
Arid3atm1b(KOMP)Wtsi
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage JAX | IMPC 0.00
Bloc1s2
Bloc1s2tm1.1(KOMP)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Brap
Brapem1(IMPC)Mbp
HET E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Cacna1s
Cacna1stm1.1(KOMP)Vlcg
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Cacna1s
Cacna1stm1.1(KOMP)Vlcg
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Ccdc186
Ccdc186em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Ccdc186
Ccdc186em1(IMPC)Mbp
HET E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Cep290
Cep290em1(IMPC)Mbp
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage UC Davis | IMPC 0.00
Cgn
Cgntm1b(KOMP)Wtsi
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage JAX | IMPC 0.00
Dlx3
Dlx3em1(IMPC)Mbp
HET E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Dnmt3b
Dnmt3bem1(IMPC)Mbp
HET E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Dnmt3b
Dnmt3bem1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Eif4h
Eif4htm1b(EUCOMM)Wtsi
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage BCM | IMPC 0.00
Enkur
Enkurem1(IMPC)Mbp
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage UC Davis | IMPC 0.00
Faf2
Faf2em1(IMPC)Mbp
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage UC Davis | IMPC 0.00
Fermt3
Fermt3tm1b(KOMP)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Fuz
Fuzem1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Got2
Got2em1(IMPC)Mbp
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage UC Davis | IMPC 0.00
Gxylt1
Gxylt1em1(IMPC)Bay
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage BCM | IMPC 0.00
Hmg20a
Hmg20aem1(IMPC)J
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Ift172
Ift172tm2b(EUCOMM)Hmgu
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage BCM | IMPC 0.00
Ift52
Ift52em1(IMPC)Bay
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage BCM | IMPC 0.00
Jun
Junem1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Kcnj13
Kcnj13tm1b(KOMP)Wtsi
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage BCM | IMPC 0.00
Kif1b
Kif1btm1b(KOMP)Wtsi
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Memo1
Memo1tm1b(EUCOMM)Wtsi
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage BCM | IMPC 0.00
Mllt10
Mllt10em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Myh10
Myh10em1(IMPC)J
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage JAX | IMPC 0.00
Myh10
Myh10em1(IMPC)J
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Nmnat2
Nmnat2em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Nog
Nogem1(IMPC)Mbp
HOM E9.5 hemorrhage Gross Morphology Embryo E9.5 | Hemorrhage UC Davis | IMPC 0.00
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Pfdn1
Pfdn1em1(IMPC)J
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Phgdh
Phgdhtm1b(KOMP)Wtsi
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage KMPC | IMPC 0.00
Phgdh
Phgdhtm1b(KOMP)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage KMPC | IMPC 0.00
Psen1
Psen1tm1.1(KOMP)Vlcg
HOM E18.5 hemorrhage Gross Morphology Embryo E18.5 | Hemorrhage JAX | IMPC 0.00
Pskh1
Pskh1tm1b(EUCOMM)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Pygo2
Pygo2tm1b(EUCOMM)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage TCP | IMPC 0.00
Rasa3
Rasa3tm1b(KOMP)J
HOM E12.5 hemorrhage Gross Morphology Embryo E12.5 | Hemorrhage JAX | IMPC 0.00
Robo2
Robo2em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Slc12a5
Slc12a5em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Spi1
Spi1tm2b(EUCOMM)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Strn3
Strn3tm1b(KOMP)Wtsi
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Tgfbr3
Tgfbr3em1(IMPC)Mbp
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Togaram1
Togaram1em1(IMPC)J
HOM E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage JAX | IMPC 0.00
Znhit6
Znhit6em1(IMPC)Mbp
HET E15.5 hemorrhage Gross Morphology Embryo E14.5-E15.5 | Hemorrhage UC Davis | IMPC 0.00
Zhx3
Zhx3tm1.1(KOMP)Vlcg
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 3.80×10-13
Awat2
Awat2em1(IMPC)Mbp
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 5.94×10-13
Awat2
Awat2em1(IMPC)Mbp
HEM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 6.17×10-12
Nhlh2
Nhlh2tm1b(KOMP)Mbp
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 1.38×10-09
Ypel3
Ypel3tm1.1(KOMP)Vlcg
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 7.86×10-09
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 7.96×10-09
Ucp1
Ucp1m1H
HOM Early adult eye hemorrhage Slit Lamp | Eye (+) blood presence MRC Harwell | EuroPhenome 1.37×10-08
Rabl2
Rabl2tm1.1(KOMP)Wtsi
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 3.30×10-08
Ablim1
Ablim1tm1H
HOM Early adult eye hemorrhage Slit Lamp | Eye (+) blood presence MRC Harwell | EuroPhenome 8.43×10-08
Diaph3
Diaph3tm1b(KOMP)Mbp
HET Late adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence JAX | IMPC 2.48×10-07
Rbp4
Rbp4tm1.1(KOMP)Vlcg
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 2.55×10-07
Dzank1
Dzank1tm1b(KOMP)Wtsi
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 9.59×10-07
Pfkfb4
Pfkfb4tm1b(KOMP)Wtsi
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 1.01×10-06
Cd36
Cd36em1(IMPC)Mbp
HOM   Late adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 3.24×10-06
Kdm3a
Kdm3aem1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 4.47×10-06
Lyplal1
Lyplal1tm1b(KOMP)Wtsi
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 4.54×10-06
Neurl4
Neurl4em1(IMPC)Mbp
HOM   Late adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 1.06×10-05
Adamts1
Adamts1em1(IMPC)Mbp
HET   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 1.26×10-05
Adgrl4
Adgrl4em1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 1.26×10-05
Pld4
Pld4em1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 2.16×10-05
Csmd3
Csmd3em1(IMPC)Mbp
HOM Late adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 2.19×10-05
Tmem145
Tmem145em1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 2.45×10-05
Spp1
Spp1tm1.1(KOMP)Vlcg
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence JAX | IMPC 2.55×10-05
Tmem163
Tmem163em1(IMPC)Mbp
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 3.09×10-05
Pus1
Pus1em1(IMPC)J
HOM Late adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence JAX | IMPC 3.11×10-05
M6pr
M6prem1(IMPC)Mbp
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 4.61×10-05
Vstm2a
Vstm2aem1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 4.63×10-05
Map3k9
Map3k9em1(IMPC)Mbp
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 5.78×10-05
Hacd3
Hacd3em1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 6.49×10-05
Disc1
Disc1em1(IMPC)Mbp
HOM   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 6.87×10-05
Eif4ebp3
Eif4ebp3tm1.1(KOMP)Vlcg
HOM Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 8.75×10-05
Slc39a7
Slc39a7tm1b(KOMP)Mbp
HET   Early adult eye hemorrhage Eye Morphology | Eye Hemorrhage or Blood Presence UC Davis | IMPC 9.30×10-05

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 The way we measure

 Phenotype associations stats

7.27% of tested genes with null mutations on a B6N genetic background have a phenotype association to hemorrhage (75/1031)

6.11% females (49/802) 6.81% males (53/778)

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