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Phenotype: increased body weight

Definition
greater than normal average weight
Synonyms
increased weight,  high body weight
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased body weight

Total number of significant genotype-phenotype associations: 21

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Kptn
Kptntm1a(EUCOMM)Wtsi 		HOM Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 6.77×10-14
Trnt1
Trnt1tm1a(EUCOMM)Hmgu 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 9.36×10-11
Ndufaf6
Ndufaf6tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.35×10-10
Cdh1
Cdh1tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
EuroPhenome		 1.43×10-06
Ppp3ca
Ppp3catm2e(EUCOMM)Wtsi 		HOM Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 2.12×10-06
Tmem132b
Tmem132bem1(IMPC)Ccpcz 		HOM Early adult increased body weight Weight
Lung mechanics by forced oscillations		 CCP-IMG
IMPC		 2.98×10-06
Pip4p1
Pip4p1em1(IMPC)Ccpcz 		HOM   Early adult increased body weight Weight
Lung mechanics by forced oscillations		 CCP-IMG
IMPC		 1.14×10-05
Kdm8
Kdm8tm1a(EUCOMM)Wtsi 		HET   Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 1.57×10-05
Foxp2
Foxp2tm2.1Woen 		HET Early adult increased body weight Body weight
Spontaneous breathing (GMC)		 HMGU
EuroPhenome		 2.18×10-05
Magi2
Magi2tm1Grnt 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
MGP		 2.19×10-05
Bpnt2
Bpnt2tm1a(KOMP)Wtsi 		HET   Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 2.67×10-05
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu 		HOM Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 2.98×10-05
Mta3
Mta3tm3a(KOMP)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 WTSI
EuroPhenome		 4.63×10-05
Sdhc
Sdhctm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Heart Dissection		 WTSI
MGP		 5.11×10-05
Frmd5
Frmd5tm1a(EUCOMM)Hmgu 		HOM Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.81×10-05
Xbp1
Xbp1tm1a(EUCOMM)Wtsi 		HET Early adult increased body weight Body Weight
Body Weight		 HMGU
EuroPhenome		 5.98×10-05
Mfrp
Mfrptm1a(KOMP)Wtsi 		HOM   Early adult increased body weight Body Weight
Hot Plate		 WTSI
MGP		 8.80×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Grip Strength
Heart Weight
Indirect Calorimetry
Organ Weight
Acoustic Startle&PPI
Age monitoring
Auditory Brain Stem Response
Body Composition (DEXA lean/fat)
Body Weight
Bodyweight (GMC)
Challenge Whole Body Plethysmography
Clickbox
Clinical Blood Chemistry
DEXA
Dexa-scan analysis
Dysmorphology
ERG (Electroretinogram) (GMC)
Eye size (GMC)
Fasted Bleed
Food efficiency (GMC)
Grip Strength (GMC)
Grip-Strength
Heart Dissection
Heart weight/tibia length
Holeboard (GMC)
Hot Plate
IPGTT
Indirect ophthalmoscopy
Insulin Blood Level
Insulin t=0
Intraperitoneal glucose tolerance test (IPGTT)
Lung mechanics by forced oscillations
Non-Invasive blood pressure
Rotarod
Rotarod B (GMC)
SHIRPA
Shirpa (GMC)
Simplified IPGTT
Spontaneous breathing (GMC)
Terminal Bleed

 Phenotype associations stats

2.09% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased body weight (17/815)

1.08% females (10/928) 0.75% males (7/933)

Select a parameter    



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