Definition
any structural anomaly of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves
Synonyms
cranial nerve dysplasia
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal cranial nerve morphology
Total number of significant genotype-phenotype associations: 126
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Angptl4 Angptl4tm1b(EUCOMM)Hmgu |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
MRC Harwell IMPC |
0.00 | |
| Atg9b Atg9btm1b(KOMP)Mbp |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Bnip3 Bnip3em1(IMPC)Mbp |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Cacna1f Cacna1ftm1.1(KOMP)Vlcg |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Ccdc25 Ccdc25em1(IMPC)Mbp |
HET | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Crbn Crbntm1b(KOMP)Wtsi |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Dsc3 Dsc3tm1b(EUCOMM)Wtsi |
HET | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
MRC Harwell IMPC |
0.00 | |
| Gpx7 Gpx7tm1.1(KOMP)Vlcg |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Krit1 Krit1tm1.1(KOMP)Vlcg |
HET | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Npas2 Npas2em1(IMPC)Mbp |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Phldb2 Phldb2em1(IMPC)H |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
MRC Harwell IMPC |
0.00 | |
| Prepl Preplem1(IMPC)H |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
MRC Harwell IMPC |
0.00 | |
| Rbm20 Rbm20em1(IMPC)Mbp |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Timp4 Timp4em1(IMPC)Mbp |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
UC Davis IMPC |
0.00 | |
| Tkfc Tkfcem1(IMPC)Ccpcz |
HOM | Early adult | abnormal optic nerve morphology | Eye with optic nerve Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Tkfc Tkfcem1(IMPC)Ccpcz |
HOM | Early adult | absent optic nerve | Eye with optic nerve Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Mettl23 Mettl23em1(IMPC)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
1.27×10-21 | |
| Bmpr1b Bmpr1bem1(IMPC)Mbp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
5.81×10-16 | |
| Pitx2 Pitx2tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
9.30×10-16 | |
| Ppfibp2 Ppfibp2em1(IMPC)Tcp |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
2.13×10-15 | |
| Nbas Nbastm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
3.95×10-15 | |
| Pepd Pepdtm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
6.75×10-15 | |
| Sh3rf1 Sh3rf1em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
1.79×10-14 | |
| Dnmbp Dnmbpem1(IMPC)Mbp |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
3.07×10-14 | |
| Bmp4 Bmp4tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
4.10×10-13 | |
| Zfp503 Zfp503em1(IMPC)Mbp |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
4.81×10-13 | |
| Gdf6 Gdf6em1(IMPC)Ccpcz |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
CCP-IMG IMPC |
1.12×10-11 | |
| Col18a1 Col18a1tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
1.44×10-11 | |
| Olfml2b Olfml2bem1(IMPC)J |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
5.68×10-11 | |
| Smoc1 Smoc1tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
6.51×10-10 | |
| Fgf10 Fgf10tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
4.16×10-09 | |
| Zbtb16 Zbtb16em1(IMPC)Mbp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
4.28×10-09 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
1.84×10-08 | |
| Tfap2b Tfap2btm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
3.74×10-08 | |
| Sox2 Sox2em1(IMPC)Mbp |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
4.04×10-08 | |
| Mettl5 Mettl5em1(IMPC)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
6.28×10-08 | |
| Stx5a Stx5atm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
9.02×10-08 | |
| Ptp4a1 Ptp4a1em2(IMPC)Tcp |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
1.23×10-07 | |
| Ehmt1 Ehmt1tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MARC IMPC |
1.62×10-07 | |
| Stoml1 Stoml1em1(IMPC)Tcp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
1.72×10-07 | |
| Trf Trfem1(IMPC)J |
HET | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
6.95×10-07 | |
| Hmcn1 Hmcn1em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
8.15×10-07 | |
| Agbl1 Agbl1em1(IMPC)J |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
9.07×10-07 | |
| Tex2 Tex2tm1.1(KOMP)Vlcg |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
9.07×10-07 | |
| Fhip2a Fhip2aem1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
9.61×10-07 | |
| Rnf168 Rnf168tm2b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
CCP-IMG IMPC |
9.83×10-07 | |
| Fbn2 Fbn2em1(IMPC)Rbrc |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
RBRC IMPC |
1.01×10-06 | |
| Dbnl Dbnltm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
ICS IMPC |
2.08×10-06 | |
| Spin1 Spin1tm1.1(KOMP)Vlcg |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
2.47×10-06 | |
| Rabgap1 Rabgap1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
2.62×10-06 | |
| Dpp3 Dpp3tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
2.73×10-06 | |
| Cib3 Cib3em1(IMPC)H |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
2.79×10-06 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
CCP-IMG IMPC |
2.99×10-06 | |
| Nxn Nxntm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MARC IMPC |
4.45×10-06 | |
| Btbd7 Btbd7em1(IMPC)Ccpcz |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
CCP-IMG IMPC |
4.65×10-06 | |
| Trim39 Trim39tm1b(EUCOMM)Hmgu |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
7.85×10-06 | |
| 1700001O22Rik 1700001O22Rikem1(IMPC)J |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
8.63×10-06 | |
| Plekhm1 Plekhm1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
9.69×10-06 | |
| Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
1.21×10-05 | |
| Rxfp2 Rxfp2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
1.48×10-05 | |
| Ahsa1 Ahsa1em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
1.56×10-05 | |
| Cdkn1b Cdkn1bem2(IMPC)H |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
1.64×10-05 | |
| Mapkapk2 Mapkapk2tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
1.64×10-05 | |
| Pard3 Pard3tm1b(KOMP)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
1.64×10-05 | |
| Nos1ap Nos1aptm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
1.77×10-05 | |
| Obp2a Obp2atm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
ICS IMPC |
1.83×10-05 | |
| Pex6 Pex6em1(IMPC)Tcp |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
1.94×10-05 | |
| Atp8b1 Atp8b1em1(IMPC)Tcp |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
2.07×10-05 | |
| Ccdc34 Ccdc34em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
2.09×10-05 | |
| Zbtb5 Zbtb5tm2b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
2.22×10-05 | |
| Spidr Spidrtm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
2.28×10-05 | |
| Aif1 Aif1tm1.1(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
2.34×10-05 | |
| Cant1 Cant1tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
2.55×10-05 | |
| Ppat Ppatem1(IMPC)Tcp |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
2.55×10-05 | |
| Plekha5 Plekha5em1(IMPC)Tcp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
2.63×10-05 | |
| Arl2bp Arl2bpem1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
2.67×10-05 | |
| Cidec Cidectm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
2.81×10-05 | |
| Egr1 Egr1tm1b(NCOM)Mfgc |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
3.01×10-05 | |
| Zfp930 Zfp930tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
3.07×10-05 | |
| Hipk4 Hipk4tm1b(KOMP)Mbp |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
3.14×10-05 | |
| Ppfia2 Ppfia2tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
3.43×10-05 | |
| Nmt2 Nmt2tm2b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
3.80×10-05 | |
| Plxna4 Plxna4em1(IMPC)Mbp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
3.86×10-05 | |
| Rcc2 Rcc2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
4.81×10-05 | |
| Shmt2 Shmt2em1(IMPC)Bay |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
5.07×10-05 | |
| Rab3gap2 Rab3gap2tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
5.31×10-05 | |
| Tmem11 Tmem11em1(IMPC)Tcp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
6.36×10-05 | |
| Zfp329 Zfp329em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
6.87×10-05 | |
| Sptlc3 Sptlc3em1(IMPC)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
HMGU IMPC |
6.92×10-05 | |
| Tshz2 Tshz2em1(IMPC)Bay |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
BCM IMPC |
6.96×10-05 | |
| Pcsk6 Pcsk6em1(IMPC)J |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
6.99×10-05 | |
| Apmap Apmapem1(IMPC)J |
HOM | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
7.27×10-05 | |
| Ik Ikem2(IMPC)Kmpc |
HET | Late adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
KMPC IMPC |
7.90×10-05 | |
| Prdm5 Prdm5em1(IMPC)Tcp |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
8.17×10-05 | |
| Sra1 Sra1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
TCP IMPC |
8.17×10-05 | |
| Zzef1 Zzef1tm2.1(KOMP)Vlcg |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
8.19×10-05 | |
| Tmem38b Tmem38bem1(IMPC)Mbp |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
UC Davis IMPC |
8.58×10-05 | |
| Dnm1l Dnm1ltm1b(KOMP)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
ICS IMPC |
8.84×10-05 | |
| Slc7a11 Slc7a11tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
ICS IMPC |
8.84×10-05 | |
| Gulo Guloem1(IMPC)Ccpcz |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
CCP-IMG IMPC |
8.88×10-05 | |
| Gbx1 Gbx1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
8.96×10-05 | |
| Kdm8 Kdm8tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
MRC Harwell IMPC |
8.96×10-05 | |
| Ap1g1 Ap1g1tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal optic disk morphology | Optic Disc Eye Morphology |
JAX IMPC |
9.30×10-05 |