Total number of significant genotype-phenotype associations: 84

Gene / Allele	Zygosity	Sex	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Kcnq3 Kcnq3em1(IMPC)H	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	3.34×10-19
Plag1 Plag1em1(IMPC)Hmgu	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	HMGU IMPC	3.61×10-17
Apex2 Apex2em1(IMPC)H	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	9.35×10-17
Slc25a21 Slc25a21tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	3.34×10-13
Erf Erftm1.1(KOMP)Mbp	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	UC Davis IMPC	2.75×10-12
Ltbp1 Ltbp1tm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	3.25×10-12
Duoxa2 Duoxa2tm1b(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	WTSI IMPC	5.11×10-12
Trabd2b Trabd2bem2(IMPC)Ccpcz	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	CCP-IMG IMPC	3.76×10-11
Setd5 Setd5tm1a(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	8.23×10-11
Usp1 Usp1tm1b(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	8.23×10-11
Daam2 Daam2tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	2.70×10-10
Daam2 Daam2tm1b(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	3.50×10-10
Celsr1 Celsr1Scy	HET		Early adult	abnormal snout morphology	muzzle/snout length Dysmorphology	MRC Harwell EuroPhenome	6.48×10-10
Smoc1 Smoc1tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	9.78×10-10
P3h2 P3h2em1(IMPC)H	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	1.32×10-09
Cdh11 Cdh11em1(IMPC)Mbp	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	UC Davis IMPC	1.80×10-09
Zc3hc1 Zc3hc1tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	1.72×10-08
Cyb561 Cyb561tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	3.37×10-08
Ifitm1 Ifitm1tm1b(EUCOMM)Wtsi	HOM		Late adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	5.38×10-08
Nog Nogem1(IMPC)Mbp	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	UC Davis IMPC	6.45×10-08
Mef2b Mef2btm2b(EUCOMM)Hmgu	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	6.47×10-08
Bcorl1 Bcorl1em1(IMPC)Tcp	HEM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	TCP IMPC	9.17×10-08
Rab3gap2 Rab3gap2tm1b(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	JAX IMPC	1.98×10-07
F7 F7tm1b(EUCOMM)Hmgu	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	1.99×10-07
Hbs1l Hbs1ltm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	WTSI IMPC	2.36×10-07
Spred1 Spred1em1(IMPC)Ccpcz	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	CCP-IMG IMPC	4.85×10-07
Vangl2 Vangl2Lp	HET		Early adult	abnormal snout morphology	muzzle/snout length Dysmorphology	MRC Harwell EuroPhenome	5.08×10-07
Npr2 Npr2em1(IMPC)H	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	6.34×10-07
Mplkip Mplkiptm1.1(KOMP)Vlcg	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	UC Davis IMPC	8.73×10-07
Lrrk1 Lrrk1tm1b(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	9.19×10-07
Os9 Os9tm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	2.73×10-06
Gsk3a Gsk3atm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	3.32×10-06
Agap1 Agap1tm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	3.54×10-06
Exoc3l2 Exoc3l2tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	3.54×10-06
Nxn Nxntm1b(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	3.54×10-06
Gmds Gmdstm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	WTSI IMPC	6.10×10-06
Rhobtb3 Rhobtb3tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	6.50×10-06
Appbp2 Appbp2em1(IMPC)J	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	JAX IMPC	8.07×10-06
Hsp90aa1 Hsp90aa1tm1(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	1.24×10-05
Bcorl1 Bcorl1em1(IMPC)Tcp	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	TCP IMPC	1.48×10-05
Irx3 Irx3em2(IMPC)H	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	2.01×10-05
Npr2 Npr2em1(IMPC)H	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	2.01×10-05
Sorl1 Sorl1tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	2.01×10-05
Marchf6 Marchf6tm1b(EUCOMM)Hmgu	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	CCP-IMG IMPC	2.18×10-05
Miga2 Miga2tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	2.25×10-05
2510009E07Rik 2510009E07Rikem1(IMPC)Ccpcz	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	CCP-IMG IMPC	2.42×10-05
Nsd3 Nsd3tm1b(EUCOMM)Hmgu	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	2.72×10-05
Klhdc2 Klhdc2tm1b(EUCOMM)Hmgu	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	2.84×10-05
Nsun2 Nsun2tm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI EuroPhenome	3.37×10-05
Rnf168 Rnf168em1(IMPC)H	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	3.78×10-05
Eps8l2 Eps8l2tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	3.80×10-05
Hipk2 Hipk2tm2b(EUCOMM)Hmgu	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	4.90×10-05
Micu1 Micu1tm1bNarl	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	4.90×10-05
Sirt1 Sirt1tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	4.90×10-05
Hoxa2 Hoxa2tm1b(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	HMGU IMPC	5.03×10-05
Pes1 Pes1tm1b(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	5.06×10-05
Sox14 Sox14em1(IMPC)Ccpcz	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	CCP-IMG IMPC	5.13×10-05
E2f3 E2f3tm1b(KOMP)Wtsi	HET		Late adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	KMPC IMPC	5.58×10-05
Lztr1 Lztr1tm1a(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	5.59×10-05
Ropn1l Ropn1ltm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	5.59×10-05
Sfpq Sfpqtm1a(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	5.59×10-05
Aff3 Aff3tm1a(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	5.93×10-05
Bcl3 Bcl3tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	5.95×10-05
Abhd5 Abhd5tm1a(KOMP)Wtsi	HOM		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI EuroPhenome	6.24×10-05
Smc3 Smc3tm1a(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	6.24×10-05
Fer Ferem1(IMPC)Tcp	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	TCP IMPC	6.96×10-05
H13 H13tm1b(KOMP)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Combined SHIRPA and Dysmorphology	WTSI IMPC	7.53×10-05
Tcf7l1 Tcf7l1tm1a(EUCOMM)Wtsi	HET		Early adult	abnormal snout morphology	Snout morphology Dysmorphology	WTSI MGP	8.38×10-05
E2f3 E2f3tm1b(KOMP)Wtsi	HET		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	KMPC IMPC	9.56×10-05
Ctdsp1 Ctdsp1tm1b(EUCOMM)Wtsi	HOM		Early adult	abnormal snout morphology	Snout size Combined SHIRPA and Dysmorphology	MRC Harwell IMPC	9.67×10-05