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Phenotype: thin ventricular wall

Definition decreased depth of the cardiac wall of the heart ventricles

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Phenotype associations stats

1.24% of tested genes with null mutations on a B6N genetic background have a phenotype association to thin ventricular wall (15/1212)

1.25% females (15/1198) 1.29% males (12/929)

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Gene variants with thin ventricular wall

Total number of significant genotype-phenotype associations: 27

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ints6l
Ints6lem1(IMPC)Marc 		HEM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 5.26E-9
Phf21b
Phf21bem1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 9.88E-7
Rnf10
Rnf10tm1b(KOMP)Wtsi 		HOM Female Male postnatal thin ventricular wall Echo | LVPWd ICS | IMPC 1.3E-6
Nr1d1
Nr1d1tm1(KOMP)Vlcg 		HOM Female Male postnatal thin ventricular wall Echo | LVAWs BCM | IMPC 2.29E-6
Wfdc11
Wfdc11em1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 2.77E-6
Defb43
Defb43tm1b(KOMP)Wtsi 		HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 2.89E-6
Esr2
Esr2em1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 4.45E-6
Hilpda
Hilpdaem1(IMPC)Mhzh 		HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 1.08E-5
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi 		HET Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 2.35E-5
Ints6l
Ints6lem1(IMPC)Marc 		HOM Female postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 3.92E-5
Ins1
Ins1em1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 4.29E-5
Trim37
Trim37em1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 4.84E-5
Vav2
Vav2em1(IMPC)Marc 		HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 4.94E-5
Usp26
Usp26em1(IMPC)Marc 		HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 6.46E-5
Acsm1
Acsm1em1(IMPC)Mhzh 		HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 6.91E-5
Emc10
Emc10tm1b(EUCOMM)Wtsi 		HOM Female postnatal thin ventricular wall Echo | LVPWd MRC Harwell | IMPC 8.66E-5

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