Phenotype: thin ventricular wall

Definition
decreased depth of the cardiac wall of the heart ventricles
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with thin ventricular wall

Total number of significant genotype-phenotype associations: 33

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Usp26
Usp26em1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVAWs MARC | IMPC 3.50×10-11
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM Early adult thin ventricular wall Echo | LVAWs BCM | IMPC 1.43×10-10
Ints6l
Ints6lem1(IMPC)Marc
HEM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 2.36×10-08
Adtrp
Adtrpem1(IMPC)Bay
HOM Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 2.02×10-07
Efcab14
Efcab14tm1b(KOMP)Wtsi
HOM Early adult thin ventricular wall Echo | LVAWs BCM | IMPC 8.23×10-07
Phf8
Phf8em1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVAWs MARC | IMPC 8.91×10-07
Vav2
Vav2em1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 2.21×10-06
Mybbp1a
Mybbp1atm1b(EUCOMM)Hmgu
HET Early adult thin ventricular wall Echo | LVPWd HMGU | IMPC 3.15×10-06
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult thin ventricular wall Echo | LVPWd ICS | IMPC 3.40×10-06
Ccdc83
Ccdc83em1(IMPC)Marc
HOM Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 4.81×10-06
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HET   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 6.98×10-06
Anks1
Anks1tm1b(KOMP)Wtsi
HOM Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 7.13×10-06
Chst12
Chst12em1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 7.78×10-06
Pgls
Pglsem1(IMPC)Bay
HET Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 8.13×10-06
Pja2
Pja2tm1b(EUCOMM)Wtsi
HOM Early adult thin ventricular wall Echo | LVAWs BCM | IMPC 1.41×10-05
Polr1a
Polr1atm1b(EUCOMM)Hmgu
HET Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 2.50×10-05
Trim37
Trim37em1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 2.95×10-05
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM   Early adult thin ventricular wall Echo | LVPWd MRC Harwell | IMPC 3.13×10-05
Hilpda
Hilpdaem1(IMPC)Mhzh
HOM Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 3.27×10-05
Ppp2r5e
Ppp2r5eem1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 4.08×10-05
Ints6l
Ints6lem1(IMPC)Marc
HOM   Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 4.26×10-05
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
HOM Early adult thin ventricular wall Echo | LVAWs MARC | IMPC 4.78×10-05
Abhd3
Abhd3em1(IMPC)Marc
HOM Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 4.83×10-05
Rbm11
Rbm11em1(IMPC)Marc
HOM Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 4.89×10-05
Acsm1
Acsm1em1(IMPC)Mhzh
HOM   Early adult thin ventricular wall Echo | LVAWs MARC | IMPC 5.78×10-05
Ccdc178
Ccdc178tm1b(EUCOMM)Wtsi
HOM Early adult thin ventricular wall Echo | LVAWs BCM | IMPC 6.04×10-05
Oscar
Oscartm1b(KOMP)Wtsi
HOM   Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 6.08×10-05
Phf21b
Phf21bem1(IMPC)Marc
HOM Early adult thin ventricular wall Echo | LVAWs MARC | IMPC 6.49×10-05
Esr2
Esr2em1(IMPC)Marc
HOM Early adult thin ventricular wall Echo | LVPWd MARC | IMPC 6.56×10-05
Zfp488
Zfp488em1(IMPC)Bay
HOM Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 7.80×10-05
Snai3
Snai3tm2b(EUCOMM)Hmgu
HOM   Early adult thin ventricular wall Echo | LVAWs BCM | IMPC 7.98×10-05
Cenpt
Cenptem1(IMPC)Bay
HET   Early adult thin ventricular wall Echo | LVPWd BCM | IMPC 9.08×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.81% of tested genes with null mutations on a B6N genetic background have a phenotype association to thin ventricular wall (31/1716)

0.53% females (9/1695) 0.70% males (10/1423)

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