The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
| Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
|---|---|---|---|---|---|---|
| abnormal neural tube morphology | Ubcem1(IMPC)Mbp | HOM | E9.5 | 0.00 | ||
| prenatal lethality prior to heart atrial septation | Ubcem1(IMPC)Mbp | HOM | E15.5 | 0.00 | ||
| abnormal neural tube morphology | Ubcem1(IMPC)Mbp | HET | E9.5 | 0.00 | ||
| abnormal neural tube closure | Ubcem1(IMPC)Mbp | HET | E9.5 | 0.00 | ||
| preweaning lethality, complete penetrance | Ubcem1(IMPC)Mbp | HOM | Early adult | 0.00 |
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Ubc by phenotypic similarity.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Ubc
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| MGI Allele | Allele Type | Produced |
|---|---|---|
| Ubcem1(IMPC)Mbp | Whole-gene deletion | Mice, Tissue |
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