Gene: Sst

Order

Name somatostatin

Synonyms
  • SOM
  • preprosomatostatin
  • SRIF
  • Smst

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:98326    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Sst

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Sst data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
improved glucose tolerance Ssttm1b(KOMP)Wtsi HOM Female Male postnatal 1.62E-6
increased circulating serum albumin level Ssttm1b(KOMP)Wtsi HOM Male postnatal 2.22E-6
decreased circulating alkaline phosphatase level Ssttm1b(KOMP)Wtsi HOM Female Male postnatal 3.46E-6
decreased bone mineral content Ssttm1b(KOMP)Wtsi HOM Male postnatal 1.24E-5
abnormal bone structure Ssttm1b(KOMP)Wtsi HOM Male postnatal 5.22E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 Yes (2/415)
Aorta 4 No
Bone 4 Yes
Brain 4 Yes (6/6)
Brainstem 4 No (6/6)
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 Yes (12/383) (6/6)
Cerebellum 4 No (6/6)
Cerebral cortex 4 No (6/6)
Chest bone 4 Yes
Colon 4 No (12/127) (6/6)
Cranium 4 No
Diaphragm 4 No
Duodenum 4 Yes (2/127) (6/6)
Epididymis 4 Yes (18/134)
Esophagus 4 No (7/415)
Eye 4 No
Gall bladder 4 Yes
Gonadal fat pad 4 No
Harderian gland 4 Yes
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No (6/6)
Hypothalamus 4 No (6/6)
Ileum 4 Yes (14/127) (6/6)
Jejunum 4 Yes (6/127) (6/6)
Kidney 4 Yes (18/584)
Large intestine 4 Yes (10/584) (6/6)
Liver 4 Yes
Lower urinary tract 4 No
Lung 4 Yes
Lymph node 4 Yes
Main olfactory bulb 4 Yes (6/6)
Mammary gland 4 No
Mesenteric lymph node 4 Yes
Mesenteric adipose tissue 4 No
Midbrain 4 No (6/6)
Olfactory lobe 4 No (6/6)
Oral epithelium 4 No
Ovary 4 Yes (1/584)
Oviduct 4 Yes
Pancreas 4 Yes (5/584) (6/6)
Parathyroid gland 4 No
Parotid gland 4 Yes
Penis 4 No
Peripheral nervous system 4 No
Peyer's patch 4 No
Pituitary gland 4 Yes
Prostate gland 4 Yes (12/584)
Quadriceps 4 No
Sciatic nerve 4 No
Skeletal muscle 4 No
Skin 4 Yes
Small intestine 4 No (9/584) (6/6)
Spinal cord 4 Yes (6/6)
Spleen 4 Yes (2/584)
Stomach 4 Yes (12/584) (6/6)
Stomach pyloric region 4 No
Striatum 4 No (6/6)
Sublingual gland 4 Yes
Submandibular gland 4 Yes (2/132)
Testis 4 Yes (2/584) (3/6)
Thalamus 4 No (6/6)
Thymus 4 Yes
Thyroid gland 4 Yes (15/584)
Tongue 4 Yes (5/127) (6/6)
Trachea 4 Yes
Trigeminal V nerve 4 Yes
Urinary bladder 4 Yes
Uterus 4 Yes
Vagina 4 Yes (3/6)
Vas deferens 4 No (15/388)
Vascular system 4 No
Vesicular gland 4 Yes
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    nervous system
    sensory organ
    reproductive system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 12 (6/485)
Ear 12 (1/485)
Embryo 12 (1/485) (12/12)
Eye 12 (1/485)
Foot 12 (1/485)
Forearm 12 (1/282)
Forebrain 12 (1/485)
Forelimb 12 (1/485)
Hand 12 (1/485)
Head 12 (5/485) (12/12)
Heart 12 (1/485)
Hindbrain 12 (6/485)
Hindlimb 12 (1/485)
Liver 12 (1/485)
Lower leg 12 (1/282)
Lung 12 (1/485)
Mandibular process 12 (1/485) (8/12)
Maxillary process 12 (1/485)
Midbrain 12 (1/485)
Oral cavity 12 (1/485)
Skin 12 (1/485)
Tail 12 (1/485)
Tail somite 12 (1/485)
Upper arm 12 (1/282)
Upper leg 12 (1/282)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    341 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
  • Embryo LacZ: LacZ images wholemount
    25 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ssttm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ssttm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene