Gene: Ptpn2

Name protein tyrosine phosphatase, non-receptor type 2

Synonyms
  • Ptpt
  • TC-PTP

Status ES CellsMice
tm1a
phenotype data available

Links MGI:97806   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Ptpn2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ptpn2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased hemoglobin content Ptpn2tm1a(EUCOMM)Wtsi HET Female Male postnatal 3.14E-6
increased mean corpuscular hemoglobin Ptpn2tm1a(EUCOMM)Wtsi HET Female Male postnatal 5.48E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (2)
  • Ptpn2tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
endocrine system (1)
  • Ptpn2tm1a(EUCOMM)Wtsi
    THYROID GLAND, HET, Female, WTSI
reproductive system (1)
  • Ptpn2tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
urinary system (1)
  • Ptpn2tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (139)
  • Ptpn2tm1a(EUCOMM)Wtsi
    HEAD, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    LOWER ARM, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    TRUNK, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    TRUNK, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    TRUNK, HET, Male, WTSI

show all 139 images

Skin Histopathology (3)
  • Ptpn2tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, WT, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, WT, Female, WTSI
Eye Morphology (2)
  • Ptpn2tm1a(EUCOMM)Wtsi
    EYE, abnormal optic disc morphology, HET, Female, WTSI
  • Ptpn2tm1a(EUCOMM)Wtsi
    EYE, abnormal optic disc morphology, HET, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ptpn2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene