Gene: Plk1

Order

Name polo like kinase 1

Synonyms
  • Plk
  • STPK13

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:97621    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Plk1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Plk1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Plk1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Plk1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Plk1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 5 (6/485)
Central nervous system ganglion 2 (1/51)
Ear 5 (1/485)
Embryo 5 (1/485)
Eye 5 (1/485)
Foot 5 (1/485)
Forebrain 5 (1/485)
Forelimb 5 (1/485)
Gut 2 (1/50)
Hand 5 (1/485)
Head 5 (5/485)
Heart 5 (1/485)
Hindbrain 5 (6/485)
Hindlimb 5 (1/485)
Liver 5 (1/485)
Lung 5 (1/485)
Mandibular process 5 (1/485)
Maxillary process 5 (1/485)
Midbrain 5 (1/485)
Nose 2 (1/51)
Oral cavity 5 (1/485)
Skeleton 2 (1/51)
Skin 5 (1/485)
Spinal cord 2 (1/50)
Tail 5 (1/485)
Tail somite 5 (1/485)
Trachea 2 (1/50)
Urinary system 2 (1/50)


Associated Images

Associated Images
  • Eye Morphology: Images Ophthalmoscopy
    6 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • Histopathology
    3 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Plk1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Plk1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene