Gene: Pde6b

Order

Name phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide

Synonyms
  • Pdeb
  • rd10
  • rd1
  • rd
  • r

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:97525    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Pde6b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pde6b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal heart morphology Pde6btm1b(KOMP)Wtsi HOM Male postnatal 0.0
enlarged heart Pde6btm1b(KOMP)Wtsi HOM Female Male postnatal 0.0
macrophthalmia Pde6b HOM Female Male postnatal 7.26E-16
abnormal whole-body plethysmography Pde6b HOM Female Male postnatal 1.57E-11
increased blood uric acid level Pde6b HOM Female Male postnatal 4.02E-10
decreased circulating amylase level Pde6b HOM Female Male postnatal 4.38E-10
increased cellular hemoglobin content Pde6b HOM Female Male postnatal 1.82E-8
decreased circulating triglyceride level Pde6b HOM Male postnatal 3.78E-8
increased mean corpuscular volume Pde6b HOM Female Male postnatal 4.37E-8
decreased body weight Pde6b HOM Female Male postnatal 1.73E-7
increased circulating potassium level Pde6b HOM Female postnatal 2.29E-6
hypoactivity Pde6b HOM Male postnatal 2.3E-6
hyperactivity Pde6btm1b(KOMP)Wtsi HOM Female Male postnatal 2.2E-5
abnormal behavior Pde6btm1b(KOMP)Wtsi HOM Female Male postnatal 8.41E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127)
Diaphragm 2 No
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127)
Jejunum 2 No (6/127)
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system sensory organ reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pde6btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Pde6btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pde6btm44764(L1L2_gt0)
Vector
Gene