Gene: Pcsk1

Order

Name proprotein convertase subtilisin/kexin type 1

Synonyms
  • Phpp-1
  • PC1
  • SPC3
  • Nec1
  • Nec-1
  • PC3
  • prohormone convertase 1/3

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:97511    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Pcsk1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pcsk1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Pcsk1tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
persistence of hyaloid vascular system Pcsk1tm1b(EUCOMM)Wtsi HET Male postnatal 4.29E-8
decreased body length Pcsk1tm1b(EUCOMM)Wtsi HET Female postnatal 1.06E-7
abnormal vitreous body morphology Pcsk1tm1b(EUCOMM)Wtsi HET Male postnatal 4.08E-7
decreased food intake Pcsk1tm1b(EUCOMM)Wtsi HET Female Male postnatal 9.79E-6
abnormal retinal blood vessel morphology Pcsk1tm1b(EUCOMM)Wtsi HET Male postnatal 3.41E-5
abnormal retinal vasculature morphology Pcsk1tm1b(EUCOMM)Wtsi HET Male postnatal 3.52E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pcsk1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Pcsk1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pcsk1tm44480(L1L2_st0)
Vector
Gene