Gene: Pax4


Name paired box 4

Synonyms Pax-4

Status ES CellsMice
phenotype data available

Links MGI:97488    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pax4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pax4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Pax4tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased circulating total protein level Pax4tm1b(EUCOMM)Hmgu HET Female Male postnatal 1.79E-6
increased circulating alkaline phosphatase level Pax4tm1b(EUCOMM)Hmgu HET Female Male postnatal 2.74E-6
increased respiratory quotient Pax4tm1b(EUCOMM)Hmgu HET Female Male postnatal 3.71E-5
increased circulating serum albumin level Pax4tm1b(EUCOMM)Hmgu HET Female Male postnatal 6.62E-5

Download data as: TSV XLS


IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485) (1/1)
Ear 1 (1/485)
Embryo 1 (1/485) Image Only
Eye 1 (1/485)
Foot 1 (1/485)
Forebrain 1 (1/485)
Forelimb 1 (1/485)
Hand 1 (1/485)
Head 1 (5/485) (1/1)
Heart 1 (1/485)
Hindbrain 1 (6/485) (1/1)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485)
Oral cavity 1 (1/485)
Pancreas 1 (1/46) (1/1)
Skin 1 (1/485)
Tail 1 (1/485)
Tail somite 1 (1/485)

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pax4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Pax4tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)