Gene: Mapt

Order

Name microtubule-associated protein tau

Synonyms
  • Mtapt
  • Tau

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:97180    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mapt

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mapt data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
polycystic kidney Mapttm1b(EUCOMM)Hmgu HOM Female postnatal 0.0
abnormal retinal blood vessel morphology Mapttm1b(EUCOMM)Hmgu HOM Male postnatal 1.13E-13
abnormal retinal vasculature morphology Mapttm1b(EUCOMM)Hmgu HOM Male postnatal 1.13E-13
persistence of hyaloid vascular system Mapttm1b(EUCOMM)Hmgu HOM Male postnatal 1.58E-10
decreased total retina thickness Mapttm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.11E-7
increased lean body mass Mapttm1b(EUCOMM)Hmgu HOM Male postnatal 2.77E-6
decreased grip strength Mapttm1b(EUCOMM)Hmgu HOM Female Male postnatal 3.11E-5
abnormal behavior Mapttm1b(EUCOMM)Hmgu HOM Female Male postnatal 6.57E-5
decreased circulating aspartate transaminase level Mapttm1b(EUCOMM)Hmgu HOM Female Male postnatal 9.57E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Pathology and Tissue Collection
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mapttm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mapttm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Mapttm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Vector
Gene