Gene: Il2ra

Order

Name interleukin 2 receptor, alpha chain

Synonyms
  • CD25
  • IL-2R alpha chain
  • Ly-43
  • Il2r

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:96549    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Il2ra

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Il2ra data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal colon morphology Il2ratm1b(EUCOMM)Wtsi HOM Male postnatal 0.0
abnormal duodenum morphology Il2ratm1b(EUCOMM)Wtsi HOM Male postnatal 0.0
abnormal spleen morphology Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 0.0
enlarged lymph nodes Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 0.0
decreased circulating HDL cholesterol level Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.32E-14
decreased heart weight Il2ratm1b(EUCOMM)Wtsi HOM Male postnatal 3.65E-9
improved glucose tolerance Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.94E-9
decreased circulating glucose level Il2ratm1b(EUCOMM)Wtsi HOM Female postnatal 6.58E-9
abnormal vertebrae morphology Il2ratm1b(EUCOMM)Wtsi HOM Female postnatal 1.14E-8
decreased circulating serum albumin level Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 9.38E-8
increased circulating phosphate level Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.27E-7
decreased circulating cholesterol level Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.38E-7
hypoactivity Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.59E-5
abnormal eye anterior chamber depth Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.01E-5
abnormal behavior Il2ratm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.29E-5
increased heart rate Il2ratm1b(EUCOMM)Wtsi HOM Female postnatal 4.22E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Pathology and Tissue Collection
    3 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Il2ratm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Il2ratm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Il2ratm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene