Gene: Il12a

Name interleukin 12a

Synonyms
  • p35
  • IL-12p35

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:96539   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Il12a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Il12a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
vertebral fusion Il12atm1b(EUCOMM)Hmgu HOM Female postnatal 1.04E-6
short tibia Il12atm1b(EUCOMM)Hmgu HOM Female postnatal 1.5E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (1/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (1/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562) (1/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    nervous system
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/440)
Ear 1 (1/440)
Embryo 1 (1/440)
Eye 1 (1/440)
Foot 1
Forebrain 1 (1/440)
Forelimb 1 (1/440)
Hand 1
Head 1 (5/440)
Heart 1 (1/440)
Hindbrain 1 (5/440)
Hindlimb 1 (1/440)
Liver 1 (1/440)
Lung 1 (1/440)
Mandibular process 1 (1/440)
Maxillary process 1 (1/440)
Midbrain 1 (1/440)
Oral cavity 1 (1/440)
Skin 1 (1/440)
Tail 1 (1/440)
Tail somite 1 (1/440)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • Echo: M-Mode Images
    28 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    7 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Il12atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Il12atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Il12atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene