Gene: Gata2

Order

Name GATA binding protein 2

Synonyms Gata-2

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:95662    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Gata2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gata2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Gata2tm1b(KOMP)Wtsi HOM Male embryonic day 9.5 0.0
abnormal embryo size Gata2tm1b(KOMP)Wtsi HET Female embryonic day 9.5 0.0
abnormal epididymis morphology Gata2tm1b(KOMP)Wtsi HET Male postnatal 0.0
abnormal ovary morphology Gata2tm1b(KOMP)Wtsi HET Female postnatal 0.0
absent epididymis Gata2tm1b(KOMP)Wtsi HET Male postnatal 0.0
embryonic growth retardation Gata2tm1b(KOMP)Wtsi HET Female embryonic day 9.5 0.0
embryonic growth retardation Gata2tm1b(KOMP)Wtsi HOM Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Gata2tm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Gata2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased or absent threshold for auditory brainstem response Gata2tm1b(KOMP)Wtsi HET Female Male postnatal 1.2E-6
decreased blood urea nitrogen level Gata2tm1b(KOMP)Wtsi HET Female Male postnatal 8.07E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127)
Diaphragm 2 No
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system digestive system reproductive system exocrine system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 3 (6/485)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 3 (1/485) (2/3)
Embryo 3 (1/485) (2/3)
Eye 3 (1/485) (2/3)
Foot 3 (1/485)
Forebrain 3 (1/485)
Forelimb 3 (1/485)
Gut 2 (1/50)
Hand 3 (1/485)
Head 3 (5/485)
Heart 3 (1/485)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485)
Liver 3 (1/485)
Lung 3 (1/485)
Mandibular process 3 (1/485)
Maxillary process 3 (1/485)
Midbrain 3 (1/485)
Nose 2 (1/51) (2/2)
Oral cavity 3 (1/485)
2 (7/25) (2/2)
Skeleton 2 (1/51)
Skin 3 (1/485)
Spinal cord 2 (1/50)
Tail 3 (1/485)
Tail somite 3 (1/485)
Trachea 2 (1/50)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Lateral Orientation
    18 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gata2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Gata2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Gata2tm209271(pL1L2_GT1_DelLacZ_bsd)
Vector
Gene