Gene: Egr1

Order

Name early growth response 1

Synonyms
  • A530045N19Rik
  • Zif268
  • Krox24
  • Krox-1
  • Egr-1
  • NGFIA
  • TIS8
  • Zfp-6
  • NGF1-A
  • Zenk
  • NGFI-A
  • Krox-24
  • ETR103

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:95295    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Egr1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Egr1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
Ovary - developmental and structural abnormality Egr1tm1b(NCOM)Mfgc HOM Female postnatal 0.0
Testes - process of degenerative change Egr1tm1b(NCOM)Mfgc HOM Male postnatal 0.0
abnormal embryo size Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
abnormal forebrain development Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
abnormal hindbrain development Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
abnormal midbrain development Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
abnormal neural tube closure Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
absent seminal vesicle Egr1tm1b(NCOM)Mfgc HOM Male postnatal 0.0
embryonic growth retardation Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Egr1tm1b(NCOM)Mfgc HOM Female Male embryonic day 12.5 0.0
female infertility Egr1tm1b(NCOM)Mfgc HOM Female postpartum stage 0.0
male infertility Egr1tm1b(NCOM)Mfgc HOM Male postpartum stage 0.0
preweaning lethality, incomplete penetrance Egr1tm1b(NCOM)Mfgc HOM Female Male n/a 0.0
small uterus Egr1tm1b(NCOM)Mfgc HOM Female postnatal 0.0
short tibia Egr1tm1b(NCOM)Mfgc HET Female Male postnatal 1.21E-9
decreased body length Egr1tm1b(NCOM)Mfgc HET Female Male postnatal 3.9E-7

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (3/3)
Brain 4 (6/485) (3/5)
Central nervous system ganglion 2 (1/51) (3/3)
Ear 4 (1/485) (3/5)
Embryo 4 (1/485) (5/5)
Eye 4 (1/485) (3/5)
Foot 4 (1/485)
Forebrain 4 (1/485) (3/5)
Forelimb 4 (1/485) (3/5)
Gut 2 (1/50) (3/3)
Hand 4 (1/485)
Head 4 (5/485) (3/5)
Heart 4 (1/485) (3/5)
Hindbrain 4 (6/485) (3/5)
Hindlimb 4 (1/485) (3/5)
Liver 4 (1/485) (3/5)
Lung 4 (1/485) (3/5)
Mandibular process 4 (1/485)
Maxillary process 4 (1/485)
Midbrain 4 (1/485) (3/5)
Nose 2 (1/51) (3/3)
Oral cavity 4 (1/485) (3/5)
2 (7/25) (3/3)
Skeleton 2 (1/51) (3/3)
Skin 4 (1/485) (3/5)
Spinal cord 2 (1/50) (3/3)
Tail 4 (1/485) (3/5)
Tail somite 4 (1/485) (3/5)
Trachea 2 (1/50) (3/3)
Urinary system 2 (1/50) (3/3)


Associated Images

Associated Images
  • Gross Pathology and Tissue Collection
    18 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • Eye Morphology: Images Ophthalmoscopy
    6 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Histopathology
    3 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Gross Morphology Embryo E9.5
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Egr1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Egr1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Egr1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Egr1tm214497(L1L2_Bact_P)
Vector
Gene