Gene: Bmi1

Order

Name Bmi1 polycomb ring finger oncogene

Synonyms
  • Bmi1
  • Bmi-1
  • Pcgf4

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:88174    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Bmi1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bmi1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
abnormal embryo size Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
abnormal embryo size Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
anophthalmia Bmi1tm1.1(KOMP)Vlcg HET Female embryonic day 15.5 0.0
edema Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
edema Bmi1tm1.1(KOMP)Vlcg HET Female Male embryonic day 15.5 0.0
microphthalmia Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
microphthalmia Bmi1tm1.1(KOMP)Vlcg HET Female Male embryonic day 15.5 0.0
prenatal lethality prior to heart atrial septation Bmi1tm1.1(KOMP)Vlcg HOM Female Male embryonic day 14.5 0.0
preweaning lethality, incomplete penetrance Bmi1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
impaired glucose tolerance Bmi1tm1.1(KOMP)Vlcg HET Male postnatal 9.67E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No (2/2)
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (1/2)
Duodenum 2 No (2/127) (1/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No (2/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (1/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (1/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No (1/2)
Mesenteric adipose tissue 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (1/2)
Parathyroid gland 2 No
Parotid gland 2 No (1/2)
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No (2/2)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (1/2)
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (1/2)
Trachea 2 No
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 4 (6/485) (2/6)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 4 (1/485) (2/6)
Embryo 4 (1/485) (2/6)
Eye 4 (1/485) (2/6)
Foot 4 (1/485) (2/6)
Forebrain 4 (1/485) (2/6)
Forelimb 4 (1/485) (2/6)
Gut 2 (1/50) (2/2)
Hand 4 (1/485) (2/6)
Head 4 (5/485) (2/6)
Heart 4 (1/485) (2/6)
Hindbrain 4 (6/485) (2/6)
Hindlimb 4 (1/485) (2/6)
Liver 4 (1/485) (2/6)
Lung 4 (1/485) (2/6)
Mandibular process 4 (1/485) (2/6)
Maxillary process 4 (1/485) (2/6)
Midbrain 4 (1/485) (2/6)
Nose 2 (1/51) (2/2)
Oral cavity 4 (1/485) (2/6)
2 (7/25) (2/2)
Skeleton 2 (1/51) (2/2)
Skin 4 (1/485) (2/6)
Spinal cord 2 (1/50) (2/2)
Tail 4 (1/485) (2/6)
Tail somite 4 (1/485) (2/6)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • Embryo LacZ: LacZ images wholemount
    16 Images
  • Gross Morphology Embryo E14.5-E15.5
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bmi1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Bmi1tm297191(L1L2_Bact_P)
Vector
Gene
Bmi1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue