Gene: Plin2

Order

Name perilipin 2

Synonyms
  • Adfp
  • ADPH
  • Adrp
  • adipophilin

Status ES CellsMice
tm1a
phenotype data available

Links MGI:87920    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Plin2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Plin2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Plin2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 2.64E-5
decreased effector memory CD4-positive, alpha-beta T cell number Plin2tm1a(EUCOMM)Wtsi HOM Female postnatal 2.69E-5
increased effector memory CD4-positive, alpha-beta T cell number Plin2tm1a(EUCOMM)Wtsi HOM Male postnatal 2.69E-5
increased mean corpuscular volume Plin2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 5.48E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562) (1/2)
Gall bladder 2 No (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (24)
  • Plin2tm1a(EUCOMM)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    peyer's patch, small intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI

show all 24 images

trunk (16)
  • Plin2tm1a(EUCOMM)Wtsi
    peyer's patch, small intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI

show all 16 images

digestive system (4)
  • Plin2tm1a(EUCOMM)Wtsi
    peyer's patch, small intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    gall bladder, liver, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
immune system (4)
  • Plin2tm1a(EUCOMM)Wtsi
    mesenteric lymph node, lymph node, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    peyer's patch, small intestine, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    spleen, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
nervous system (4)
  • Plin2tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    brain, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
reproductive system (3)
  • Plin2tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    white adipose tissue, uterus, ovary, oviduct, HET, Female, WTSI
set of connective tissues (3)
  • Plin2tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    trachea, cartilage tissue, thyroid gland, parathyroid gland, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    white adipose tissue, uterus, ovary, oviduct, HET, Female, WTSI
adipose tissue (2)
  • Plin2tm1a(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    white adipose tissue, uterus, ovary, oviduct, HET, Female, WTSI
endocrine system (2)
  • Plin2tm1a(EUCOMM)Wtsi
    adrenal gland, HET, Male, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    trachea, cartilage tissue, thyroid gland, parathyroid gland, HET, Female, WTSI
respiratory system (2)
  • Plin2tm1a(EUCOMM)Wtsi
    lung, HET, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    trachea, cartilage tissue, thyroid gland, parathyroid gland, HET, Female, WTSI
cardiovascular system (1)
  • Plin2tm1a(EUCOMM)Wtsi
    heart, HET, Female, WTSI
exocrine system (1)
  • Plin2tm1a(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
integumental system (1)
  • Plin2tm1a(EUCOMM)Wtsi
    skin, skin muscle, HET, Female, WTSI
musculoskeletal system (1)
  • Plin2tm1a(EUCOMM)Wtsi
    bone, HET, Female, WTSI
sensory organ (1)
  • Plin2tm1a(EUCOMM)Wtsi
    eye, HET, Male, WTSI
urinary system (1)
  • Plin2tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (87)
  • Plin2tm1a(EUCOMM)Wtsi
    forearm, WT, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    body, WT, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    body, WT, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    head, WT, Female, WTSI
  • Plin2tm1a(EUCOMM)Wtsi
    forearm, WT, Female, WTSI

show all 87 images

Skin Histopathology (1)
  • Plin2tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Plin2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene