Gene: Cyp2ab1

Name cytochrome P450, family 2, subfamily ab, polypeptide 1

Synonyms EG224044

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:3644957   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Cyp2ab1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cyp2ab1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal spleen morphology Cyp2ab1tm1b(KOMP)Wtsi HOM Male postnatal 0.0
decreased circulating phosphate level Cyp2ab1tm1b(KOMP)Wtsi HET Female Male postnatal 4.31E-9
decreased circulating phosphate level Cyp2ab1tm1b(KOMP)Wtsi HOM Female Male postnatal 4.31E-9
decreased circulating lactate dehydrogenase level Cyp2ab1tm1b(KOMP)Wtsi HOM Female Male postnatal 2.78E-6
decreased circulating lactate dehydrogenase level Cyp2ab1tm1b(KOMP)Wtsi HET Female Male postnatal 2.78E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 8 No (2/354)
Aorta 8 No (2/530)
Bone 8 No (1/515)
Brain 8 No (8/530)
Brainstem 8 No (5/530)
Brown adipose tissue 8 No
Cartilage tissue 8 No (1/530)
Cecum 8 No (1/325)
Cerebellum 8 No (6/530)
Cerebral cortex 8 No (6/530)
Esophagus 8 No (1/354)
Eye 8 No (1/530)
Gall bladder 8 No
Heart 8 No (4/530)
Hippocampus 8 No (7/530)
Hypothalamus 8 No (5/529)
Kidney 8 No (13/530)
Large intestine 8 No (7/530)
Liver 8 No
Lower urinary tract 8 No (3/530)
Lung 8 No (4/530)
Lymph node 8 No (2/530)
Mammary gland 8 No
Mesenteric lymph node 8 No
Olfactory lobe 8 No (3/354)
Oral epithelium 8 No
Ovary 8 No (1/530)
Oviduct 8 No (1/530)
Pancreas 8 No (2/530)
Parathyroid gland 8 No (2/516)
Peripheral nervous system 8 No (4/530)
Peyer's patch 8 No (1/354)
Pituitary gland 8 No (2/530)
Prostate gland 8 No (3/530) (2/8)
Skeletal muscle 8 No
Skin 8 No (2/530)
Small intestine 8 No (5/530)
Spinal cord 8 No (5/530)
Spleen 8 No (3/530)
Stomach 8 No (5/530)
Striatum 8 No (6/530)
Testis 8 No (7/530) (3/8)
Thymus 8 No (1/530)
Thyroid gland 8 No (11/530)
Trachea 8 No (5/530)
Trigeminal V nerve 8 No
Urinary bladder 8 No
Uterus 8 No (1/530)
Vas deferens 8 No (1/331)
Vascular system 8 No (1/354)
White adipose tissue 8 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    exocrine system
    trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    4 Images
  • X-ray: XRay Images Skull Lateral Orientation
    4 Images
  • Adult LacZ: LacZ Images Wholemount
    3 Images
  • X-ray: XRay Images Lateral Orientation
    4 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    4 Images
  • X-ray: XRay Images Dorso Ventral
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Cyp2ab1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cyp2ab1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Cyp2ab1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cyp2ab1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene