Gene: Satb2

Order

Name special AT-rich sequence binding protein 2

Synonyms BAP002

Status ES CellsMice
tm1a
Mice
em2
Mice
em3
Mice
tm1b
phenotype data available

Links MGI:2679336    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Satb2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Satb2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Satb2em3(IMPC)Tcp HOM Female Male embryonic day 15.5 0.0
abnormal uterus morphology Satb2tm1b(KOMP)Wtsi HET Female postnatal 0.0
enlarged lymph nodes Satb2tm1b(KOMP)Wtsi HET Male postnatal 0.0
preweaning lethality, complete penetrance Satb2em3(IMPC)Tcp HOM Female Male n/a 0.0
preweaning lethality, complete penetrance Satb2tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
long tibia Satb2tm1b(KOMP)Wtsi HET Female Male postnatal 1.13E-9
increased circulating alkaline phosphatase level Satb2em3(IMPC)Tcp HET Female Male postnatal 3.4E-9
increased circulating phosphate level Satb2tm1b(KOMP)Wtsi HET Female Male postnatal 6.34E-6
decreased circulating bilirubin level Satb2em3(IMPC)Tcp HET Female Male postnatal 4.36E-5
shortened QT interval Satb2tm1b(KOMP)Wtsi HET Female Male postnatal 8.08E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 1 No (18/134) (1/1)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (1/2)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system digestive system reproductive system exocrine system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Gross Pathology and Tissue Collection
    12 Images
  • Histopathology
    2 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    26 Images
  • X-ray: XRay Images Dorso Ventral
    26 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    42 Images
  • X-ray: XRay Images Hind Leg and Hip
    16 Images
  • Eye Morphology: Images Slit Lamp
    6 Images
  • Eye Morphology: Images Ophthalmoscopy
    6 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Satb2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Satb2em2(IMPC)Mbp Indel causing a Frameshift Mutation
Vector
Gene
Satb2em3(IMPC)Tcp Indel causing a Frameshift Mutation
Vector
Gene
Satb2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Satb2tm41799(L1L2_gt1)
Vector
Gene
Satb2tm41799(L1L2_gt1_Del_LacZ)
Vector
Gene