Gene: Myo18a

Order

Name myosin XVIIIA

Synonyms MyoPDZ

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2667185    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Myo18a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Myo18a data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
abnormal embryo size Myo18atm1b(KOMP)Wtsi HET Female Male embryonic day 12.5 0.0
abnormal embryo size Myo18atm1b(KOMP)Wtsi HET Female embryonic day 9.5 0.0
abnormal eye morphology Myo18atm1b(KOMP)Wtsi HET Female Male embryonic day 12.5 0.0
abnormal limb bud morphology Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
abnormal placenta size Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
embryonic lethality prior to tooth bud stage Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
pale liver Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
pale yolk sac Myo18atm1b(KOMP)Wtsi HET Female Male embryonic day 12.5 0.0
pale yolk sac Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
pallor Myo18atm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Myo18atm1b(KOMP)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 9 (6/482) Image Only
Ear 9 (1/482) Image Only
Embryo 9 (1/482) Image Only
Eye 9 (1/482) Image Only
Foot 9 (1/482) Image Only
Forebrain 9 (1/482) Image Only
Forelimb 9 (1/482) Image Only
Hand 9 (1/482) Image Only
Head 9 (5/482) Image Only
Heart 9 (1/482) Image Only
Hindbrain 9 (6/482) Image Only
Hindlimb 9 (1/482) Image Only
Liver 9 (1/482) Image Only
Lung 9 (1/482) Image Only
Mandibular process 9 (1/482) Image Only
Maxillary process 9 (1/482) Image Only
Midbrain 9 (1/482) Image Only
Oral cavity 9 (1/482) Image Only
Skin 9 (1/482) Image Only
Tail 9 (1/482) Image Only
Tail somite 9 (1/482) Image Only


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    51 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Pathology and Tissue Collection
    8 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Histopathology
    1 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • Eye Morphology: Images Slit Lamp
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Myo18atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Myo18atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Myo18atm119203(L1L2_Pgk_P)
Vector
Gene