Gene: Mat2a

Order

Name methionine adenosyltransferase II, alpha

Synonyms D630045P18Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2443731    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Mat2a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mat2a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Mat2atm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased prepulse inhibition Mat2atm1a(EUCOMM)Hmgu HET Female Male postnatal 1.05E-11
increased startle reflex Mat2atm1a(EUCOMM)Hmgu HET Female Male postnatal 7.09E-6
abnormal behavior Mat2atm1a(EUCOMM)Hmgu HET Female Male postnatal 4.76E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415)
Aorta 4 No
Bone 4 No
Brain 4 No (4/4)
Brainstem 4 No
Brown adipose tissue 4 No
Cartilage tissue 4 No
Cecum 4 No (12/383) (4/4)
Cerebellum 4 No
Cerebral cortex 4 No
Chest bone 4 No
Colon 4 No (12/127) (4/4)
Cranium 4 No
Diaphragm 4 No
Duodenum 4 No (2/127)
Epididymis 4 No (18/134)
Esophagus 4 No (7/415)
Eye 4 No
Gall bladder 4 No
Gonadal fat pad 4 No
Harderian gland 4 No (4/4)
Heart 4 No
Hindlimb 4 No
Hippocampus 4 No
Hypothalamus 4 No
Ileum 4 No (14/127)
Jejunum 4 No (6/127)
Kidney 4 No (18/584) (4/4)
Large intestine 4 No (10/584) (4/4)
Liver 4 No
Lower urinary tract 4 No
Lung 4 No
Lymph node 4 No
Main olfactory bulb 4 No
Mammary gland 4 No
Mesenteric lymph node 4 No
Mesenteric adipose tissue 4 No
Midbrain 4 No
Olfactory lobe 4 No
Oral epithelium 4 No
Ovary 4 No (1/584)
Oviduct 4 No
Pancreas 4 No (5/584)
Parathyroid gland 4 No
Parotid gland 4 No
Penis 4 No (2/4)
Peripheral nervous system 4 No (4/4)
Peyer's patch 4 No
Pituitary gland 4 No
Prostate gland 4 No (12/584)
Quadriceps 4 No
Sciatic nerve 4 No (4/4)
Skeletal muscle 4 No
Skin 4 No
Small intestine 4 No (9/584)
Spinal cord 4 No (4/4)
Spleen 4 No (2/584)
Stomach 4 No (12/584)
Stomach pyloric region 4 No
Striatum 4 No
Sublingual gland 4 No
Submandibular gland 4 No (2/132)
Testis 4 No (2/584) (2/4)
Thalamus 4 No
Thymus 4 No
Thyroid gland 4 No (15/584)
Tongue 4 No (5/127) (4/4)
Trachea 4 No
Trigeminal V nerve 4 No
Urinary bladder 4 No
Uterus 4 No
Vagina 4 No
Vas deferens 4 No (15/388)
Vascular system 4 No
Vesicular gland 4 No
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    limb
    respiratory system
    digestive system
    nervous system
    sensory organ
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 10 (6/485)
Ear 10 (1/485)
Embryo 10 (1/485)
Eye 10 (1/485)
Foot 10 (1/485)
Forearm 10 (1/282)
Forebrain 10 (1/485)
Forelimb 10 (1/485)
Hand 10 (1/485)
Head 10 (5/485)
Heart 10 (1/485)
Hindbrain 10 (6/485)
Hindlimb 10 (1/485)
Liver 10 (1/485)
Lower leg 10 (1/282)
Lung 10 (1/485)
Mandibular process 10 (1/485)
Maxillary process 10 (1/485)
Midbrain 10 (1/485)
Oral cavity 10 (1/485)
Skin 10 (1/485)
Tail 10 (1/485)
Tail somite 10 (1/485)
Upper arm 10 (1/282)
Upper leg 10 (1/282)


Associated Images

Associated Images
  • Eye Morphology: Images Ophthalmoscopy
    5 Images
  • Embryo LacZ: LacZ images wholemount
    6 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    144 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mat2atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Mat2atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mat2atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene