Gene: Slitrk4

Order

Name SLIT and NTRK-like family, member 4

Synonyms D930039I09Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2442509    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Slitrk4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slitrk4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating calcium level Slitrk4tm1b(KOMP)Wtsi HEM Male postnatal 1.23E-6
increased IgG level Slitrk4tm1b(KOMP)Wtsi HOM Female postnatal 6.98E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No
Aorta 1 No
Blood vessel 1 No
Bone 1 No
Brain 1 No (2/2)
Brainstem 1 No (2/2)
Brown adipose tissue 1 No
Cartilage tissue 1 No
Cerebellum 1 No (2/2)
Cerebral cortex 1 No (2/2)
Eye 1 No
Gall bladder 1 No
Heart 1 No
Hippocampus 1 No (2/2)
Hypothalamus 1 No (2/2)
Kidney 1 No (18/584)
Large intestine 1 No (10/584) (2/2)
Liver 1 No
Lower urinary tract 1 No
Lung 1 No
Lymph node 1 No
Mammary gland 1 No
Esophagus 1 No
Olfactory lobe 1 No (2/2)
Ovary 1 No (1/584)
Oviduct 1 No
Pancreas 1 No (5/584)
Parathyroid gland 1 No
Peripheral nervous system 1 No (2/2)
Peyer's patch 1 No
Pituitary gland 1 No
Prostate gland 1 No (12/584)
Skeletal muscle tissue 1 No
Skin 1 No
Small intestine 1 No (9/584) (2/2)
Spinal cord 1 No (2/2)
Spleen 1 No (2/584)
Stomach 1 No (12/584) (2/2)
Striatum 1 No (2/2)
Testis 1 No (2/584)
Thymus 1 No
Thyroid gland 1 No (15/584)
Trachea 1 No
Uterus 1 No
White adipose tissue 1 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse digestive system nervous system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (6)
  • Slitrk4tm1b(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    stomach, HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    brain, HET, Female, WTSI

show all 6 images

trunk (4)
  • Slitrk4tm1b(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    stomach, HEMI, Male, WTSI
digestive system (3)
  • Slitrk4tm1b(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    small intestine, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    stomach, HEMI, Male, WTSI
nervous system (3)
  • Slitrk4tm1b(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    trigeminal V nerve, peripheral nervous system, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Dorso Ventral
    43 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    4 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (71)
  • Slitrk4tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HOM, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI

show all 71 images

Brain Histopathology (7)
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    secondary somatosensory cortex, decreased secondary somatosensory cortex size, HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    HEMI, Male, WTSI

show all 7 images

Eye Morphology (4)
  • Slitrk4tm1b(KOMP)Wtsi
    abnormal cornea morphology, HEMI, Male, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    corneal opacity, HOM, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    corneal opacity, HOM, Female, WTSI
  • Slitrk4tm1b(KOMP)Wtsi
    cataracts, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slitrk4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slitrk4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene