Gene: Brcc3

Order

Name BRCA1/BRCA2-containing complex, subunit 3

Synonyms C6.1A

Status ES CellsMice
em1
Mice
em1
phenotype data available

Links MGI:2389572    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Brcc3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Brcc3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular volume Brcc3em1(IMPC)Marc HOM Female Male postnatal 7.89E-12
increased mean corpuscular hemoglobin Brcc3em1(IMPC)Marc HOM Female Male postnatal 3.05E-8
increased mean platelet volume Brcc3em1(IMPC)Marc HOM Female Male postnatal 3.18E-7
thrombocytosis Brcc3em1(IMPC)Marc HOM Female postnatal 4.19E-7
corneal opacity Brcc3em1(IMPC)Marc HOM Female postnatal 4.17E-6
decreased red blood cell distribution width Brcc3em1(IMPC)Marc HOM Female Male postnatal 3.86E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Dysmorphology (3)
  • Brcc3em1(IMPC)Wtsi
    abnormal eye morphology, narrow eye opening, head, HOM, Female, WTSI
  • Brcc3em1(IMPC)Wtsi
    head, abnormal snout morphology, asymmetric snout, HOM, Female, WTSI
  • Brcc3em1(IMPC)Wtsi
    abnormal snout morphology, asymmetric snout, head, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Brcc3em1(IMPC)Marc Exdel
Vector
Gene
Brcc3em1(IMPC)Wtsi Exdel
Vector
Gene
Brcc3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene