Gene: Tmem63b

Order

Name transmembrane protein 63b

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:2387609    Ensembl Gene    Ensembl Orthologs    My Genes    IDG   

Viability Homozygous - Lethal

Phenotype associations for Tmem63b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tmem63b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Tmem63btm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal cornea morphology Tmem63btm1b(EUCOMM)Wtsi HET Female Male postnatal 1.04E-7
abnormal behavior Tmem63btm1b(EUCOMM)Wtsi HET Female Male postnatal 1.21E-5
limb grasping Tmem63btm1b(EUCOMM)Wtsi HET Male postnatal 2.1E-5
hyperactivity Tmem63btm1b(EUCOMM)Wtsi HET Female Male postnatal 8.19E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482) (2/2)
Ear 1 (1/482) (2/2)
Embryo 1 (1/482) (2/2)
Eye 1 (1/482) (2/2)
Foot 1 (1/482) (2/2)
Forebrain 1 (1/482) (2/2)
Forelimb 1 (1/482) (2/2)
Hand 1 (1/482) (2/2)
Head 1 (5/482) (2/2)
Heart 1 (1/482) (2/2)
Hindbrain 1 (6/482) (2/2)
Hindlimb 1 (1/482) (2/2)
Liver 1 (1/482) (2/2)
Lung 1 (1/482) (2/2)
Mandibular process 1 (1/482) (2/2)
Maxillary process 1 (1/482) (2/2)
Midbrain 1 (1/482) (2/2)
Oral cavity 1 (1/482) (2/2)
1 (11/27) (2/2)
Skin 1 (1/482) (2/2)
Tail 1 (1/482) (2/2)
Tail somite 1 (1/482) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Embryo LacZ: LacZ images section
    1 Images
  • Embryo LacZ: LacZ images wholemount
    1 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tmem63btm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Tmem63btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Tmem63btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene