Gene: Lyplal1

Name lysophospholipase-like 1

Synonyms Q96AVO

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2385115   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Lyplal1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lyplal1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
vertebral fusion Lyplal1tm1a(KOMP)Wtsi HOM Male postnatal 5.91E-5
increased circulating iron level Lyplal1tm1b(KOMP)Wtsi HOM Female postnatal 8.61E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354)
Aorta 2 No (2/530)
Bone 2 No (1/515)
Brain 2 No (8/530)
Brainstem 2 No (5/530)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530)
Esophagus 2 No (1/354)
Eye 2 No (1/530)
Gall bladder 2 No
Heart 2 No (4/530)
Hippocampus 2 No (7/530)
Hypothalamus 2 No (5/529)
Kidney 2 No (13/530)
Large intestine 2 No (7/530)
Liver 2 No
Lower urinary tract 2 No (3/530)
Lung 2 No (4/530)
Lymph node 2 No (2/530)
Mammary gland 2 No
Olfactory lobe 2 No (3/354)
Oral epithelium 2 No
Ovary 2 No (1/530)
Oviduct 2 No (1/530)
Pancreas 2 No (2/530)
Parathyroid gland 2 No (2/516)
Peripheral nervous system 2 No (4/530)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530)
Small intestine 2 No (5/530)
Spinal cord 2 No (5/530)
Spleen 2 No (3/530)
Stomach 2 No (5/530)
Striatum 2 No (6/530)
Testis 2 No (7/530) (1/2)
Thymus 2 No (1/530)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530)
Uterus 2 No (1/530)
Vascular system 2 No (1/354)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413)
Ear 2
Embryo 2 (1/5)
Eye 2
Foot 2
Forebrain 2
Forelimb 2
Hand 2
Head 2 (4/413)
Heart 2
Hindbrain 2 (5/413)
Hindlimb 2
Liver 2
Lung 2
Mandibular process 2
Maxillary process 2
Midbrain 2
Oral cavity 2
Skin 2
Tail 2
Tail somite 2


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    95 Images
  • X-ray: XRay Images Lateral Orientation
    60 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    25 Images
  • X-ray: XRay Images Skull Lateral Orientation
    15 Images
  • X-ray: XRay Images Forepaw
    15 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Echo: M-Mode Images
    28 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    1 Images
Legacy Phenotype Associated Images
Xray (75)
  • Lyplal1tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    HOM, Male, WTSI

show all 75 images

Eye Morphology (6)
  • Lyplal1tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    Fused cornea and lens, HOM, Female, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Lyplal1tm1a(KOMP)Wtsi
    abnormal pupil morphology, abnormal placement of pupils, HOM, Female, WTSI

show all 6 images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Lyplal1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lyplal1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene