Gene: Slc25a28

Order

Name solute carrier family 25, member 28

Synonyms
  • Mfrn2
  • Mrs3/4
  • 2210403D18Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:2180509    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Slc25a28

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc25a28 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular hemoglobin Slc25a28tm1b(EUCOMM)Wtsi HOM Female Male postnatal 4.39E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Aorta 2 No (2/2)
Blood vessel 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (1/2)
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle tissue 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (22)
  • Slc25a28tm1b(EUCOMM)Wtsi
    pituitary gland, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    blood vessel, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    lymph node, mesenteric lymph node, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI

show all 22 images

trunk (15)
  • Slc25a28tm1b(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    aorta, HET, Male, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI

show all 15 images

digestive system (4)
  • Slc25a28tm1b(EUCOMM)Wtsi
    stomach, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    large intestine, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    gall bladder, HET, Female, WTSI
nervous system (3)
  • Slc25a28tm1b(EUCOMM)Wtsi
    pituitary gland, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    hypothalamus, HET, Male, WTSI
reproductive system (3)
  • Slc25a28tm1b(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
cardiovascular system (2)
  • Slc25a28tm1b(EUCOMM)Wtsi
    blood vessel, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    aorta, HET, Male, WTSI
respiratory system (2)
  • Slc25a28tm1b(EUCOMM)Wtsi
    trachea, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    lung, HET, Female, WTSI
urinary system (2)
  • Slc25a28tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
adipose tissue (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI
endocrine system (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
exocrine system (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    prostate gland, HET, Male, WTSI
immune system (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    lymph node, mesenteric lymph node, HET, Female, WTSI
integumental system (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    skin, HET, Female, WTSI
sensory organ (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    eye, HET, Female, WTSI
set of connective tissues (1)
  • Slc25a28tm1b(EUCOMM)Wtsi
    brown adipose tissue, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    6 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (70)
  • Slc25a28tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 70 images

Eye Morphology (6)
  • Slc25a28tm1b(EUCOMM)Wtsi
    abnormal cornea morphology, HOM, Male, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    abnormal cornea morphology, HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    corneal opacity, HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    narrow eye opening, HOM, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    Fused cornea and lens, HOM, Female, WTSI

show all 6 images

Histology Slide (5)
  • Slc25a28tm1b(EUCOMM)Wtsi
    TS20 dorsal root ganglion, HET, Male, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    TS20 skin, HET, Male, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    TS20 chorioallantoic placenta, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    TS20 spinal cord, HET, Female, WTSI
  • Slc25a28tm1b(EUCOMM)Wtsi
    TS20 stomach, HET, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc25a28tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc25a28tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene