Gene: Sec16b

Order

Name SEC16 homolog B (S. cerevisiae)

Synonyms
  • Lztr2
  • Rgpr-p117
  • Rgpr

Status ES CellsMice
tm1a
phenotype data available

Links MGI:2148802    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Sec16b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Sec16b data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased body weight Sec16btm1a(KOMP)Wtsi HOM Female Male postnatal 2.29E-11
decreased circulating HDL cholesterol level Sec16btm1a(KOMP)Wtsi HOM Female Male postnatal 8.4E-10
decreased circulating cholesterol level Sec16btm1a(KOMP)Wtsi HOM Female Male postnatal 1.53E-8

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No (1/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system cardiovascular system nervous system set of connective tissues reproductive system musculoskeletal system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (13)
  • Sec16btm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    liver, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    heart, HET, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI

show all 13 images

trunk (9)
  • Sec16btm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    liver, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    heart, HET, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    testis, HET, Male, WTSI

show all 9 images

digestive system (3)
  • Sec16btm1a(KOMP)Wtsi
    liver, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI
nervous system (2)
  • Sec16btm1a(KOMP)Wtsi
    pituitary gland, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
reproductive system (2)
  • Sec16btm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    oviduct, HET, Female, WTSI
set of connective tissues (2)
  • Sec16btm1a(KOMP)Wtsi
    cartilage tissue, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    cartilage tissue, HET, Female, WTSI
urinary system (2)
  • Sec16btm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    lower urinary tract, urinary bladder, HET, Female, WTSI
cardiovascular system (1)
  • Sec16btm1a(KOMP)Wtsi
    heart, HET, Male, WTSI
respiratory system (1)
  • Sec16btm1a(KOMP)Wtsi
    trachea, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (67)
  • Sec16btm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Sec16btm1a(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    head, HOM, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    head, HOM, Male, WTSI
  • Sec16btm1a(KOMP)Wtsi
    body, HOM, Male, WTSI

show all 67 images

Eye Morphology (1)
  • Sec16btm1a(KOMP)Wtsi
    eye, cataracts, corneal opacity, HOM, Male, WTSI
Skin Histopathology (1)
  • Sec16btm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Sec16btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Sec16btm41606(L1L2_gt0)
Vector
Gene