Gene: Sytl1

Order

Name synaptotagmin-like 1

Synonyms
  • PSGL-1
  • Slp1

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1933365    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Sytl1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Sytl1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased effector memory CD4-positive, alpha-beta T cell number Sytl1tm1a(KOMP)Wtsi HOM Female Male postnatal 3.68E-6
increased effector memory CD8-positive, alpha-beta T cell number Sytl1tm1a(KOMP)Wtsi HOM Female Male postnatal 6.8E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No
Aorta 1 No
Blood vessel 1 No
Bone 1 No
Brain 1 No (2/2)
Brainstem 1 No
Brown adipose tissue 1 No
Cartilage tissue 1 No
Cerebellum 1 No
Cerebral cortex 1 No
Eye 1 No (2/2)
Gall bladder 1 No
Heart 1 No
Hippocampus 1 No
Hypothalamus 1 No
Kidney 1 No (18/584)
Large intestine 1 No (10/584)
Liver 1 No
Lower urinary tract 1 No (1/2)
Lung 1 No
Lymph node 1 No
Mammary gland 1 No
Esophagus 1 No (2/2)
Olfactory lobe 1 No
Ovary 1 No (1/584)
Oviduct 1 No (1/2)
Pancreas 1 No (5/584) (1/2)
Parathyroid gland 1 No
Peripheral nervous system 1 No
Peyer's patch 1 No
Pituitary gland 1 No
Prostate gland 1 No (12/584)
Skeletal muscle tissue 1 No
Skin 1 No (2/2)
Small intestine 1 No (9/584)
Spinal cord 1 No
Spleen 1 No (2/584)
Stomach 1 No (12/584) (2/2)
Striatum 1 No
Testis 1 No (2/584) (1/2)
Thymus 1 No
Thyroid gland 1 No (15/584) (1/2)
Trachea 1 No
Uterus 1 No
White adipose tissue 1 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system digestive system nervous system sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (9)
  • Sytl1tm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    stomach, oesophagus, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    skin, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    eye, HET, Female, WTSI

show all 9 images

trunk (4)
  • Sytl1tm1a(KOMP)Wtsi
    stomach, oesophagus, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    pancreas, HOM, Male, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    testis, HOM, Male, WTSI
reproductive system (2)
  • Sytl1tm1a(KOMP)Wtsi
    oviduct, HET, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    testis, HOM, Male, WTSI
digestive system (1)
  • Sytl1tm1a(KOMP)Wtsi
    stomach, oesophagus, HET, Female, WTSI
endocrine system (1)
  • Sytl1tm1a(KOMP)Wtsi
    thyroid gland, HOM, Male, WTSI
integumental system (1)
  • Sytl1tm1a(KOMP)Wtsi
    skin, HET, Female, WTSI
nervous system (1)
  • Sytl1tm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
sensory organ (1)
  • Sytl1tm1a(KOMP)Wtsi
    eye, HET, Female, WTSI
urinary system (1)
  • Sytl1tm1a(KOMP)Wtsi
    lower urinary tract, HOM, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (122)
  • Sytl1tm1a(KOMP)Wtsi
    forearm, HOM, Male, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    body, HOM, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    head, HOM, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    body, HOM, Male, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    body, HOM, Male, WTSI

show all 122 images

Skin Histopathology (3)
  • Sytl1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Sytl1tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Sytl1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Sytl1tm44240(L1L2_gt1)
Vector
Gene
Sytl1tm44240(L1L2_gt2)
Vector
Gene