Gene: Prrg2

Order

Name proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

Synonyms
  • 2510041M06Rik
  • N4WBP1
  • 1600014G02Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1929596    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Prrg2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Prrg2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating iron level Prrg2tm1b(EUCOMM)Wtsi HOM Female postnatal 4.23E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system cardiovascular system nervous system reproductive system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (7)
  • Prrg2tm1b(EUCOMM)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    THYMUS, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    HEART, HET, Female, WTSI

show all 7 images

reproductive system (2)
  • Prrg2tm1b(EUCOMM)Wtsi
    OVARY, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
urinary system (2)
  • Prrg2tm1b(EUCOMM)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HET, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
cardiovascular system (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
endocrine system (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    PARATHYROID GLAND, HET, Female, WTSI
immune system (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    THYMUS, HET, Female, WTSI
integumental system (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    SKIN, HET, Female, WTSI
nervous system (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    PITUITARY GLAND, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    43 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • DSS Histology
    8 Images
  • Ear epidermis immunophenotyping
    11 Images
  • Anti-nuclear antibody assay
    6 Images
Legacy Phenotype Associated Images
Xray (71)
  • Prrg2tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Prrg2tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI

show all 71 images

Eye Morphology (1)
  • Prrg2tm1b(EUCOMM)Wtsi
    corneal vascularization, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Prrg2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Prrg2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Prrg2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene