Gene: Cib2

Name calcium and integrin binding family member 2

Synonyms
  • 2810434I23Rik
  • calcium binding protein Kip2

Status ES CellsMice
tm1b
Mice
tm1c
Mice
tm1a
phenotype data available

Links MGI:1929293   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Cib2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cib2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
polycystic kidney Cib2tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
absent startle reflex Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.4E-19
decreased startle reflex Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.03E-14
increased circulating cholesterol level Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 4.23E-10
abnormal ear morphology Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.12E-9
increased circulating HDL cholesterol level Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.07E-7
decreased prepulse inhibition Cib2tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.1E-6
limb grasping Cib2tm1b(EUCOMM)Wtsi HOM Female postnatal 3.86E-6
tremors Cib2tm1b(EUCOMM)Wtsi HOM Male postnatal 7.35E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No (2/354)
Aorta 3 No (2/530)
Bone 3 No (1/515)
Brain 3 No (8/530) (3/3)
Brainstem 3 No (5/530) (2/3)
Brown adipose tissue 3 No (2/3)
Cartilage tissue 3 No (1/530)
Cerebellum 3 No (6/530)
Cerebral cortex 3 No (6/530) (3/3)
Esophagus 3 No (1/354)
Eye 3 No (1/530)
Gall bladder 3 No
Heart 3 No (4/530)
Hippocampus 3 No (7/530) (3/3)
Hypothalamus 3 No (5/529) (3/3)
Kidney 3 No (13/530)
Large intestine 3 No (7/530)
Liver 3 No
Lower urinary tract 3 No (3/530)
Lung 3 No (4/530)
Lymph node 3 No (2/530)
Mammary gland 3 No
Olfactory lobe 3 No (3/354) (3/3)
Oral epithelium 3 No
Ovary 3 No (1/530)
Oviduct 3 No (1/530)
Pancreas 3 No (2/530)
Parathyroid gland 3 No (2/516) (2/3)
Peripheral nervous system 3 No (4/530)
Peyer's patch 3 No (1/354)
Pituitary gland 3 No (2/530)
Prostate gland 3 No (3/530)
Skeletal muscle 3 No
Skin 3 No (2/530)
Small intestine 3 No (5/530)
Spinal cord 3 No (5/530) (2/3)
Spleen 3 No (3/530)
Stomach 3 No (5/530)
Striatum 3 No (6/530)
Testis 3 No (7/530) (1/3)
Thymus 3 No (1/530)
Thyroid gland 3 No (11/530)
Trachea 3 No (5/530)
Uterus 3 No (1/530)
Vascular system 3 No (1/354)
White adipose tissue 3 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    nervous system
    set of connective tissues
    reproductive system
    adipose tissue
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (5/413) (3/5)
Ear 3
Embryo 3 (4/5)
Eye 3 (1/5)
Foot 3 (3/5)
Forebrain 3 (3/5)
Forelimb 3 (3/5)
Hand 3 (3/5)
Head 3 (4/413) (3/5)
Heart 3
Hindbrain 3 (5/413) (3/5)
Hindlimb 3 (3/5)
Liver 3
Lung 3 (1/5)
Mandibular process 3
Maxillary process 3
Midbrain 3 (3/5)
Oral cavity 3
Skin 3
Tail 3
Tail somite 3


Associated Images

Associated Images
  • Echo: M-Mode Images
    79 Images
  • Adult LacZ: LacZ Images Wholemount
    7 Images
  • X-ray: XRay Images Lateral Orientation
    21 Images
  • X-ray: XRay Images Dorso Ventral
    32 Images
  • X-ray: XRay Images Hind Leg and Hip
    12 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Cib2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Cib2tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp)
Vector
Gene
Cib2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cib2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene