Gene: Svep1

Order

Name sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

Synonyms
  • 4833413O10Rik
  • D430029O09Rik
  • Polydom
  • 1110021D17Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1928849    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Svep1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Svep1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal limb morphology Svep1tm1b(EUCOMM)Hmgu HOM Male embryonic day 18.5 0.0
abnormal skin appearance Svep1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 18.5 0.0
abnormal tail morphology Svep1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 18.5 0.0
edema Svep1tm1b(EUCOMM)Hmgu HOM Female embryonic day 15.5 0.0
edema Svep1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 18.5 0.0
embryonic lethality prior to tooth bud stage Svep1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Svep1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased total body fat amount Svep1tm1b(EUCOMM)Hmgu HET Male postnatal 1.51E-6
decreased circulating phosphate level Svep1tm1b(EUCOMM)Hmgu HET Female Male postnatal 5.97E-6
increased hematocrit Svep1tm1b(EUCOMM)Hmgu HET Female Male postnatal 2.58E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system digestive system reproductive system immune system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (1/2)
Dorsal root ganglion 1 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (1/2)
Eye 2 (1/485)
Foot 2 (1/485) (1/2)
Forebrain 2 (1/485) (1/2)
Forelimb 2 (1/485) (1/2)
Fronto-nasal process 1 (1/48)
Hand 2 (1/485) (1/2)
Head 2 (5/485) (1/2)
Heart 2 (1/485) (1/2)
Hindbrain 2 (6/485) (1/2)
Hindlimb 2 (1/485) (1/2)
Liver 2 (1/485)
Lung 2 (1/485) (1/2)
Mandibular process 2 (1/485) (1/2)
Maxillary process 2 (1/485) (1/2)
Midbrain 2 (1/485) (1/2)
Nose 1 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485) (1/2)
Spinal cord 1 (1/50)
Tail 2 (1/485) (1/2)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Morphology Embryo E14.5-E15.5
    4 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images
  • Gross Morphology Embryo E18.5
    4 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Svep1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Svep1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene