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Gene: Trip4 MGI:1928469

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Gene Summary

Name:
thyroid hormone receptor interactor 4
Synonyms:
ASC-1,  4930558E03Rik

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IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

VIP of left fundus

16 Images

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Eye Morphology

VIP of right fundus

16 Images

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MicroCT E18.5

Embryo reconstruction

8 Images

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Eye Morphology

VIP of left eye

16 Images

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Eye Morphology

VIP of right eye

16 Images

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Human diseases caused by Trip4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Trip4 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Spinal Muscular Atrophy With Congenital Bone Fractures 1
OMIM:616866
Congenital Muscular Dystrophy-Respiratory Failure-Skin Abnormalities-Joint Hyperlaxity Syndrome
ORPHA:486815
Muscular Dystrophy, Congenital, Davignon-Chauveau Type
OMIM:617066

The table below shows human diseases predicted to be associated to Trip4 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Spinal Muscular Atrophy With Congenital Bone Fractures 1
OMIM:616866
Congenital Muscular Dystrophy-Respiratory Failure-Skin Abnormalities-Joint Hyperlaxity Syndrome
ORPHA:486815
Muscular Dystrophy, Congenital, Davignon-Chauveau Type
OMIM:617066

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Trip4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Trip4.

No publications found that use IMPC mice or data for Trip4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Trip4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Trip4tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Trip4em1(IMPC)Bay Exon Deletion Mice

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