Gene: Wdr12

Order

Name WD repeat domain 12

Synonyms
  • Ytm1p
  • 4933402C23Rik
  • Ytm1

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1927241    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Wdr12

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Wdr12 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to tooth bud stage Wdr12tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Wdr12tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
abnormal coat/hair pigmentation Wdr12tm1.1(KOMP)Vlcg HET Female Male postnatal 9.4E-8
decreased coping response Wdr12tm1.1(KOMP)Vlcg HET Female Male postnatal 7.57E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (1/2)
Dorsal root ganglion 1 (1/47) (1/1)
Ear 2 (1/485) (2/2)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485) (2/2)
Foot 2 (1/485) (1/2)
Forebrain 2 (1/485) (1/2)
Forelimb 2 (1/485) (2/2)
Fronto-nasal process 1 (1/48) Image Only
Hand 2 (1/485) (1/2)
Head 2 (5/485) (2/2)
Heart 2 (1/485) (2/2)
Hindbrain 2 (6/485) (1/2)
Hindlimb 2 (1/485) (2/2)
Liver 2 (1/485) (2/2)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/2)
Maxillary process 2 (1/485) (2/2)
Midbrain 2 (1/485) (1/2)
Nose 1 (1/51) (1/1)
Oral cavity 2 (1/485) (1/2)
Skin 2 (1/485) (2/2)
Spinal cord 1 (1/50) (1/1)
Tail 2 (1/485) (2/2)
Tail somite 2 (1/485) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Electroretinography: Cone waveform (pdf format)
    4 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • Electroretinography: Rod waveform (pdf format)
    4 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Combined SHIRPA and Dysmorphology
    7 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Wdr12tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Wdr12tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Wdr12tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene